Trials / Completed
CompletedNCT02718664
Food-effect Study on Uracil and Dihydrouracil Levels as a Diagnostic Marker of Dihydropyrimidine Dehydrogenase Activity
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- The Netherlands Cancer Institute · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
Healthy volunteer food-effect study to determine the effect of food on uracil and dihydrouracil levels in plasma
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Test meal (breakfast) | Standardized test meal, in accordance with high-fat and high-calorie meal as described in the FDA guidance, but ingredients are changed to Dutch standards and ingredients are added that are expected to have the largest effects on dihydrouracil and uracil levels |
Timeline
- Start date
- 2016-04-14
- Primary completion
- 2017-06-01
- Completion
- 2017-12-01
- First posted
- 2016-03-24
- Last updated
- 2025-08-03
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT02718664. Inclusion in this directory is not an endorsement.