| Not Yet Recruiting | rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder NCT05974202 | New York State Psychiatric Institute | N/A |
| Recruiting | Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder NCT07318480 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction NCT06125054 | Dr. med. Marcus Herdener | Phase 2 |
| Unknown | Randomized, Double-blind, Placebo-controlled Cannabis Extract x Placebo for Cocaine Addicts NCT06159387 | University of Sao Paulo General Hospital | Phase 4 |
| Active Not Recruiting | Clavulanic Acid for the Treatment of Cocaine Use Disorder NCT05562349 | Temple University | Phase 2 |
| Unknown | Effect of rTMS on Neurotrophines Levels in CUD NCT05824221 | ITAB - Institute for Advanced Biomedical Technologies | N/A |
| Unknown | Low-Intensity Focused Ultrasound for Cocaine Use Disorder NCT05857852 | University of Virginia | N/A |
| Completed | rTMS for Stimulant Use Disorders NCT04907357 | Medical University of South Carolina | N/A |
| Recruiting | Effect of HF rTMS on Serum BDNF in Cocaine Use Disorder NCT06189690 | Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente | N/A |
| Completed | TDCS to Reduce Craving in Cocaine Addiction- Phase 2 Study NCT04994821 | Soterix Medical | Phase 2 |
| Completed | Pharmaco-Magnetic Resonance Spectroscopy (MRS) Study of Clavulanic Acid NCT04411914 | Temple University | Phase 1 |
| Completed | TDCS for Cocaine Addiction Craving NCT03833583 | Soterix Medical | N/A |
| Completed | Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo Using 11UCB-J PET NCT03527485 | Yale University | N/A |
| Withdrawn | Rebalancing the Serotonergic System in Cocaine Dependence NCT03266939 | Mclean Hospital | Phase 1 |
| Completed | Investigation of Cocaine Addiction Using mGluR5 PET and fMRI NCT03471182 | Yale University | Phase 1 |
| Unknown | Transcranial Magnetic Stimulation for Cocaine Addiction NCT03333460 | ITAB - Institute for Advanced Biomedical Technologies | N/A |
| Completed | Neurobehavioral Measurement of Substance Users in Outpatient Treatment Setting NCT03662529 | Hunter Holmes Mcguire Veteran Affairs Medical Center | N/A |
| Terminated | Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use NCT02927236 | National Institute on Drug Abuse (NIDA) | N/A |
| Completed | Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study NCT02563769 | Temple University | Phase 1 |
| Terminated | Effects of Glucocorticoids on Craving During Detoxification Treatment of Heroin and/or Stimulants NCT02935101 | Prof. Dominique de Quervain, MD | Phase 2 |
| Completed | 10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence NCT03238859 | Medical University of South Carolina | Phase 2 |
| Completed | Cannabidiol and Cocaine Craving/Dependence NCT02559167 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 2 |
| Completed | Change the Cycle: An RCT to Prevent Injection Initiation NCT02774954 | University of Southern California | N/A |
| Completed | Functional Magnetic Resonance Imaging of N-acetylcysteine in Cocaine Dependence NCT02994875 | Yale University | EARLY_Phase 1 |
| Completed | Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine Users NCT03554928 | Medical University of South Carolina | — |
| Completed | Complementary Combination Therapy for Cocaine Dependence NCT02538744 | Baylor College of Medicine | Phase 1 |
| Completed | Investigation of Intranasal Oxytocin on Relapse Risk in Cocaine-dependent Patients. NCT02255357 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | Predicting Relapse After Cocaine Inpatient Cessation NCT02416050 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration NCT02302976 | Yale University | Phase 1 |
| Completed | Imaging the Neurobiology of Behavioral and Medication Treatment for Cocaine Dependence NCT01468012 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | PET Imaging in Cocaine Self Administration NCT02181491 | Yale University | N/A |
| Completed | Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence NCT02111798 | Johns Hopkins University | Phase 2 / Phase 3 |
| Withdrawn | A PET Exploration of the Mechanism of Action of Dopamine Beta-hydroxylase Inhibition in Cocaine Addicts NCT02134002 | Assistance Publique - Hôpitaux de Paris | Phase 4 |
| Completed | 5HT2CR Balance in Brain Connectivity in Cocaine Dependence NCT03921151 | Virginia Commonwealth University | Phase 1 / Phase 2 |
| Completed | n-Acetylcysteine and Cocaine NCT02141620 | University of Kentucky | EARLY_Phase 1 |
| Terminated | Understanding Dopamine Mechanisms in Cocaine Addiction Using AMPT and Methylphenidate With [11C]RAC/[11C]PHNO NCT02152670 | Yale University | N/A |
| Completed | Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse NCT01953432 | VA Office of Research and Development | Phase 2 |
| Completed | Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS NCT02124941 | Yale University | Phase 1 |
| Withdrawn | D-Serine for Cocaine Dependence Pilot NCT01715051 | Theresa Winhusen | Phase 2 |
| Completed | Striatal Effective Connectivity to Predict Treatment Response in Cocaine Misuse NCT02080819 | Virginia Commonwealth University | Phase 2 |
| Completed | A Sequenced Behavioral and Medication Intervention for Cocaine Dependence NCT01986075 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | Impact of a Non-Drug Choice on Cocaine Reinforcement NCT01906346 | Joshua A. Lile, Ph.D. | EARLY_Phase 1 |
| Withdrawn | A Study of Baclofen ER NCT02003664 | University of Pennsylvania | Phase 2 |
| Completed | Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use i NCT02018263 | Yale University | Phase 1 |
| Completed | Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence NCT01811940 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | The Effect of Glutamatergic Modulation on Cocaine Self-administration NCT02596022 | New York State Psychiatric Institute | Phase 2 |
| Completed | A Multi-Center Trial of Nepicastat for Cocaine Dependence NCT01704196 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Completed | A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocai NCT01846481 | Indivior Inc. | Phase 2 |
| Terminated | A Pilot Study of Candesartan as a Treatment for Cocaine Dependence NCT01938664 | Baylor College of Medicine | Phase 2 |
| Terminated | A Drug Treatment for Cocaine Users Who Are Also on Methadone Maintenance Treatment NCT01802515 | Yale University | N/A |
| Completed | Impulsivity and Stimulant Administration NCT01978431 | Yale University | Phase 1 |
| Withdrawn | Progesterone and Atomoxetine for Cocaine Cessation NCT01741376 | University of Minnesota | N/A |
| Withdrawn | Tacrine Effects on Cocaine Self-Administration and Pharmacokinetics NCT01406522 | Midwest Biomedical Research Foundation | Phase 2 |
| Completed | Oxytocin in Cocaine Dependence NCT01573273 | Medical University of South Carolina | N/A |
| Completed | A Phase II Trial of Varenicline for the Treatment of Cocaine Dependence NCT01680887 | University of Pennsylvania | Phase 2 |
| Completed | Study of Buspirone for Relapse-Prevention in Adults With Cocaine Dependence NCT01641159 | University of Cincinnati | Phase 2 |
| Completed | Pharmacologic MRI in Cocaine Addiction NCT01652378 | University of Texas Southwestern Medical Center | — |
| Recruiting | Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals NCT02455479 | Weill Medical College of Cornell University | Phase 1 |
| Completed | Behavioral Incentives to Increase Exercise in Cocaine Dependent Women NCT01283191 | Virginia Commonwealth University | N/A |
| Terminated | The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence NCT01535937 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | Exercise as an Adjunctive Treatment for Cocaine Dependent Patients NCT01832649 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | N/A |
| Completed | Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence NCT01486810 | New York State Psychiatric Institute | Phase 1 / Phase 2 |
| Completed | Pramipexole as a Treatment for Cocaine Dependence NCT01651377 | Baylor College of Medicine | Phase 1 |
| Completed | Cocaine Use Reduction With Buprenorphine NCT01402492 | University of California, Los Angeles | Phase 2 / Phase 3 |
| Completed | Exercise as a Behavioral Treatment for Cocaine Dependence NCT01601743 | Baylor College of Medicine | N/A |
| Completed | PHASE IIA: Trial of a Novel Ondansetron Formulation (OND-PR002) and Immediate-Release Methylphenidate (Ritalin NCT01377662 | Tong Lee | Phase 2 |
| Completed | A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence NCT01651364 | Baylor College of Medicine | Phase 1 |
| Terminated | Pilot Study of Lisdexamfetamine for Treatment of Cocaine Dependence NCT01490216 | University of Minnesota | Phase 1 |
| Completed | Effect of Oxytocin on Stress Response in Cocaine-dependent Individuals NCT01963091 | Medical University of South Carolina | Phase 2 |
| Completed | Cognitive Remediation for Cocaine Dependence NCT01393457 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | Cocaine/Crack and Reduction of Compulsion With Biperiden NCT01251393 | Federal University of São Paulo | Phase 3 |
| Unknown | Neuropsychological Rehabilitation on Cocaine/Crack Dependents NCT01914835 | University of Sao Paulo General Hospital | N/A |
| Terminated | Vigabatrin for Cocaine and Alcohol Dependence NCT01335867 | University of Pennsylvania | Phase 2 |
| Completed | Psychopharmacology for Cocaine Dependence - Buspirone NCT01267292 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | Glutamatergic Modulation of Cocaine-related Deficits NCT01790490 | New York State Psychiatric Institute | Phase 2 |
| Completed | Progesterone for Postpartum Cocaine Relapse NCT01249274 | Yale University | N/A |
| Completed | Vigabatrin for the Treatment of Cocaine Dependency NCT01281202 | Catalyst Pharmaceuticals, Inc. | Phase 2 / Phase 3 |
| Completed | Citalopram for Cocaine Dependence NCT01535573 | Joy Schmitz | Phase 2 |
| Completed | Ovarian Hormones and Stress Induced Drug Craving NCT02098434 | Medical University of South Carolina | N/A |
| Completed | HBPL Study of the Impact of the NK1 Antagonist Aprepitant NCT01176591 | University of Pennsylvania | Phase 2 |
| Completed | Carvedilol for Psychostimulant Dependence NCT01171183 | University of Arkansas | Phase 2 |
| Completed | Modafinil - Escitalopram Study for Cocaine Dependence NCT01601730 | Baylor College of Medicine | Phase 1 |
| Completed | Multisite Controlled Trial of Cocaine Vaccine NCT00969878 | Baylor College of Medicine | Phase 2 |
| Completed | Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving NCT01151813 | University of Pennsylvania | Phase 2 |
| Completed | Trial of Citicoline Therapy in Patients With Mania or Hypomania and Cocaine Abuse/Dependence NCT00223236 | University of Texas Southwestern Medical Center | Phase 3 |
| Completed | Cocaine Use Disorder and Cortical Dopamine NCT03349606 | University of Pittsburgh | EARLY_Phase 1 |
| Completed | Effect of Zonisamide on Cocaine Reinforcement, Craving, and Relapse NCT01137890 | Johns Hopkins University | Phase 1 / Phase 2 |
| Withdrawn | Human Behavioral Pharmacology Laboratory Study of Varenicline's Impact on Cocaine Reinforcement NCT01143857 | Jennifer Plebani | Phase 2 |
| Completed | Investigation of Mifepristone (RU486) on Stress Sensitivity and Relapse Prevention in Cocaine Dependent Patien NCT01134198 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | Modafinil, Sleep Architecture and Cocaine Relapse NCT01137396 | Yale University | Phase 2 |
| Unknown | Repetitive Transcranial Magnetic Stimulation in Symptoms of Attention Deficit Hyperactivity Disorder and Cogni NCT01593982 | University of Sao Paulo General Hospital | Phase 2 |
| Unknown | Study of the Effect of Magnetic Stimulation Repetitive Transcranial on Impulsivity in Cocaine Dependence NCT01397266 | University of Sao Paulo General Hospital | Phase 2 |
| Completed | Pharmacogenetics of Doxazosin for Cocaine Dependence NCT01145183 | Baylor College of Medicine | Phase 2 |
| Completed | Smoking-Cessation and Stimulant Treatment (S-CAST) NCT01077024 | University of Cincinnati | Phase 3 |
| Completed | Brain Function and Structure in Cocaine Dependence NCT02080832 | Virginia Commonwealth University | Phase 2 |
| Completed | The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine NCT01062945 | Baylor College of Medicine | Phase 1 |
| Completed | Measuring Distress Tolerance With Functional MRI NCT01038232 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Abstinence-Linked Money Management Multisite NCT01327586 | Yale University | Phase 2 |
| Completed | Effectiveness of Extended Treatment for Drug Dependence (ETDD) in the City Study NCT01153464 | University of Pennsylvania | Phase 2 |
| Completed | Effectiveness of Enhanced Treatments for Drug Dependence NCT01153477 | University of Pennsylvania | Phase 2 |
| Completed | The Efficacy of Doxazosin for Cocaine Users NCT00880997 | Baylor College of Medicine | Phase 1 |
| Completed | Risk Perception in Drug-Dependent Adults With and Without Schizophrenia NCT01031563 | National Institute on Drug Abuse (NIDA) | — |
| Terminated | Brain Glutamate Receptors and Cocaine Dependence NCT00951314 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Treatment of Cocaine Dependence With Lisdexamfetamine NCT00958282 | University of Minnesota | Phase 2 |
| Completed | VIVITROL as a Treatment for Cocaine and Alcohol Dependence NCT00777062 | University of Pennsylvania | Phase 2 |
| Completed | Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction NCT00701532 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Modafinil for Smoked Cocaine Self-Administration NCT01778010 | New York State Psychiatric Institute | Phase 2 |
| Completed | Beta-blockade Effects on Memory for Cocaine Craving NCT00830362 | Medical University of South Carolina | Phase 2 |
| Completed | Gender and Neural Substrates of Stress and Craving NCT00756925 | Medical University of South Carolina | — |
| Completed | Rivastigmine and Huperzine A as Treatments for Cocaine Dependence NCT01030692 | Baylor College of Medicine | Phase 1 |
| Unknown | Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence NCT00495183 | Hospital Universitari Vall d'Hebron Research Institute | Phase 4 |
| Completed | An fMRI Study of SYN115 in Cocaine Dependent Subjects NCT00783276 | Virginia Commonwealth University | EARLY_Phase 1 |
| Completed | Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336 in Healthy, Male Subjec NCT00808119 | RTI International | Phase 1 |
| Unknown | A Double-Blind, Controlled Study of Aripiprazole in Co-Morbid Schizophrenia and Cocaine Dependence NCT00737256 | Paul Saenger | Phase 2 |
| Completed | New Medication Treatment for Stimulant Dependence NCT00689572 | University of Virginia | Phase 2 |
| Completed | Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers NCT00656357 | Biotie Therapies Inc. | Phase 1 / Phase 2 |
| Completed | Clinical Neurobiology of Serotonin and Addiction NCT00732901 | Virginia Commonwealth University | Phase 2 / Phase 3 |
| Completed | Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients NCT00780702 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Completed | Pharmacotherapy & CM for Opioid and Cocaine Dependence NCT00838981 | Yale University | Phase 1 / Phase 2 |
| Completed | Citicoline for Bipolar 1 Disorder and Cocaine Dependence NCT00619723 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Caffeine and Cocaine NCT00733993 | Virginia Commonwealth University | Phase 1 / Phase 2 |
| Completed | Quetiapine for the Reduction of Cocaine Use NCT00631748 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Completed | Progesterone Treatment for Cocaine-dependent Women: A Pilot Study NCT00632099 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | Vigabatrin for Treatment of Cocaine Dependence NCT00611130 | Catalyst Pharmaceuticals, Inc. | Phase 2 |
| Completed | Carbidopa/Levodopa Combined With Behavioral Therapy for the Treatment of Cocaine Dependence NCT00713583 | The University of Texas Health Science Center, Houston | Phase 2 |
| Terminated | Effects of Propranolol on Responses to Drug-Related Imagery Scripts NCT00688805 | National Institute on Drug Abuse (NIDA) | Phase 1 |
| Completed | Study of Adderall-XR for the Treatment of Adult Attention Deficit Hyperactivity Disorder and Cocaine Dependenc NCT00553319 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | Chantix for Treating Cocaine Dependence NCT00567008 | University of Pennsylvania | Phase 2 |
| Unknown | Treating Cocaine Abuse: A Behavioral Approach NCT01822327 | University of Vermont | Phase 2 |
| Completed | A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction NCT00567814 | Embera NeuroTherapeutics, Inc. | N/A |
| Completed | Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse NCT00809835 | Yale University | Phase 2 |
| Unknown | Pharmacotherapy for HIV+ Stimulant Dependent Individuals NCT00599573 | University of Virginia | N/A |
| Completed | Sex Differences in Progesterone Effects on Responses to Stress and Drug Cues NCT00585520 | Yale University | Phase 1 |
| Completed | Cocaine Withdrawal and Pharmacotherapy Response NCT00566969 | Yale University | N/A |
| Completed | Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained Patients NCT00577005 | Yale University | Phase 2 |
| Completed | Effectiveness of Extended Treatments for Drug Dependence NCT00685659 | University of Pennsylvania | N/A |
| Completed | Double Blind Study of Vigabatrin for the Treatment of Cocaine Dependence NCT00527683 | NYU Langone Health | Phase 2 |
| Completed | Impulsivity, Neural Deficits and Cocaine Addiction NCT00744601 | University of Texas Southwestern Medical Center | — |
| Completed | Disulfiram for Cocaine Abuse NCT00395850 | University of Arkansas | Phase 2 |
| Completed | Efficacy of Varenicline in Methadone-Stabilized Cocaine Users NCT00567320 | Yale University | N/A |
| Unknown | Novel Pharmacotherapy for Dual Dependence NCT00448825 | Bankole Johnson | Phase 3 |
| Completed | Clinical Trial of Topiramate for Cocaine Addiction NCT00685178 | Johns Hopkins University | Phase 2 |
| Completed | A Placebo-Controlled Study of Mixed Amphetamine Salts and Topiramate for the Treatment of Cocaine Dependence NCT00421603 | New York State Psychiatric Institute | Phase 2 |
| Completed | Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients. NCT00593125 | Yale University | Phase 2 |
| Completed | Pilot Trial of Acamprosate for the Treatment of Cocaine Dependence NCT00385268 | University of Pennsylvania | Phase 2 |
| Completed | Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior NCT00368290 | Kyle Kampman | Phase 2 |
| Completed | Modafinil, Sleep, and Cognition in Cocaine Dependence NCT00582491 | Yale University | N/A |
| Completed | Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence NCT00376558 | New York State Psychiatric Institute | N/A |
| Completed | Agonist Replacement Therapy for Cocaine Dependence NCT00697138 | University of Kentucky | Phase 1 |
| Completed | Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression NCT00249444 | New York State Psychiatric Institute | Phase 2 |
| Terminated | Effects of Vigabatrin on Cocaine Self-Administration NCT00373581 | New York State Psychiatric Institute | Phase 2 |
| Completed | Valproate Efficacy in Cocaine-Bipolar Comorbidity NCT00240110 | University of Miami | Phase 1 / Phase 2 |
| Completed | Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine Dependency NCT00280293 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Clinical Efficacy of Sertraline Augmented With Gabapentin in Depressed, Recently Abstinent Cocaine-dependent H NCT00654953 | University of Arkansas | Phase 2 |
| Completed | Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1 NCT00218491 | Medical University of South Carolina | Phase 2 |
| Completed | An Add-On Trial of Quetiapine in Patients With Bipolar Disorder and Cocaine Dependence NCT00223210 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence NCT00344565 | Research Foundation for Mental Hygiene, Inc. | Phase 2 |
| Recruiting | Substance Abuse Pre-Treatment Screening Study NCT00439049 | The University of Texas Health Science Center, Houston | — |
| Completed | Efficacy of Mirtazapine in Depressed Cocaine Dependent Subjects NCT00322309 | Boston University | Phase 2 |
| Completed | Study of the Effects of Risperdal Consta on Brain Reward Circuitry Function, Craving and Cocaine Use in Active NCT00385801 | Massachusetts General Hospital | Phase 2 |
| Completed | FMRI of Stress and Addictive Disorders NCT01558973 | Yale University | — |
| Unknown | Randomised Placebo-Controlled Trial of Modafinil for Cocaine Dependence NCT00123383 | The University of New South Wales | Phase 2 |
| Completed | Metabolic Effects of Cocaine NCT00451230 | National Institute on Drug Abuse (NIDA) | N/A |
| Completed | Reward Processing in Cocaine Addiction NCT01036074 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2 NCT00249535 | UConn Health | N/A |
| Completed | Pharmacogenetics of Disulfiram for Cocaine NCT00149630 | Baylor College of Medicine | Phase 2 |
| Completed | Long Term Maintenance of Drug Abstinence NCT00842517 | Treatment Research Institute | Phase 1 |
| Completed | Topiramate for Alcohol and Cocaine Dependence NCT00167245 | Kyle Kampman | Phase 2 |
| Completed | Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1 NCT00218387 | Medical University of South Carolina | Phase 2 |
| Terminated | Prazosin for ETOH or Cocaine Craving NCT00240227 | US Department of Veterans Affairs | N/A |
| Completed | Enhanced and Attendance-based Prize CM in Community Settings NCT00606853 | UConn Health | N/A |
| Completed | Combined Treatment for Cocaine-Alcohol Dependence - 1 NCT00218569 | The University of Texas Health Science Center, Houston | Phase 2 |
| Completed | Gender Differences in Response to Cues in Cocaine Dependence NCT00969943 | Medical University of South Carolina | — |
| Completed | Therapeutic Cocaine Vaccine: Human Laboratory Study NCT00965263 | New York State Psychiatric Institute | Phase 2 |
| Completed | A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence NCT00227123 | University of Texas Southwestern Medical Center | N/A |
| Completed | Cost Effective Treatment for Dually Diagnosed Homeless NCT00368524 | University of Alabama at Birmingham | N/A |
| Completed | Serotonin, Impulsivity, and Cocaine Dependence Treatment NCT00297505 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Completed | Integrated Treatment for Cocaine and Mood Disorders - 1 NCT00227812 | National Institute on Drug Abuse (NIDA) | Phase 2 |
| Completed | Disulfiram for Cocaine Abuse in Buprenorphine Treatment NCT00913484 | Yale University | Phase 2 |
| Completed | PET Assays of Striatal Dopamine Marker in Cocaine Craving NCT01036516 | National Institute on Drug Abuse (NIDA) | — |
| Completed | Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence - 1 NCT00218660 | University of Pennsylvania | Phase 3 |
| Completed | Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1 NCT00061087 | New York State Psychiatric Institute | Phase 2 / Phase 3 |
| Completed | Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence NCT00167232 | University of Pennsylvania | Phase 3 |
| Completed | Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2 NCT00249457 | Johns Hopkins University | N/A |
| Completed | Behavioral Treatment for Cocaine Dependent Women NCT00914381 | Yale University | Phase 2 |
| Terminated | First in Humans Study of JDTic NCT01431586 | RTI International | Phase 1 |
| Completed | Effectiveness and Costs of Enhanced Cocaine Treatments NCT00167258 | University of Pennsylvania | Phase 2 |