Trials / Completed
CompletedNCT00656357
Study of Safety and Potential Efficacy of SYN117 in Cocaine Dependent Volunteers
A Human Laboratory Assessment of the Safety and Potential Efficacy of SYN117 (Nepicastat) in Cocaine-dependent Volunteers Receiving Cocaine
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Biotie Therapies Inc. · Industry
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
This study will assess the potential interaction and subjective effects between intravenous cocaine and SYN117 in non-treatment seeking cocaine dependant subjects
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | SYN117 Placebo | Placebo |
| DRUG | SYN117 80 mg | SYN117 80 mg |
| DRUG | SYN117 160 mg | SYN117 160 mg |
| DRUG | Cocaine 10mg | IV Cocaine 10mg |
| DRUG | Cocaine 20mg | IV Cocaine 20mg |
| DRUG | Cocaine 40mg | IV Cocaine 40mg |
| DRUG | Saline | IV Cocaine Placebo |
Timeline
- Start date
- 2008-06-01
- Primary completion
- 2009-05-01
- Completion
- 2009-05-01
- First posted
- 2008-04-11
- Last updated
- 2018-08-17
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00656357. Inclusion in this directory is not an endorsement.