NCT00368290

Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior

Modafinil Treatment for Cocaine Dependence and HIV-High Risk Behavior

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 94 (actual)
• Sponsor: Kyle Kampman · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of study is to determine if modafinil promotes cocaine abstinence and reduces high risk behavior in cocaine dependent subjects.

Detailed description

The purpose of study is to determine if modafinil promotes cocaine abstinence and reduces HRB in cocaine dependent subjects. Modafinil (300 mg/day) or placebo will be administered in an 8-week double-blind trial to patients meeting diagnostic criteria for cocaine dependence in conjunction with Cognitive Behavioral Therapy (CBT).

Conditions

• Cocaine Dependence

Interventions

Type	Name	Description
DRUG	Modafinil	300mg a day for 8 weeks
DRUG	placebo	placebo pills for 8 weeks
BEHAVIORAL	Cognitive Behavioral Therapy (CBT)	Weekly cognitive behavioral therapy sessions for a period of 8 weeks.

Timeline

• Start date: 2006-09-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2006-08-24
• Last updated: 2018-03-15
• Results posted: 2014-01-29