NCT00061087

Treatment of Adult Attention Deficit Hyperactivity Disorder (ADHD) in Methadone Patients - 1

Treatment of Adult ADHD in Methadone Patients

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 115 (actual)
• Sponsor: New York State Psychiatric Institute · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to treat Adult Attention Deficit Hyperactivity Disorder (ADHD) in methadone patients.

Detailed description

This project is a three armed double-blind, placebo-controlled, randomized trial comparing the efficacy of MPH and BPR, relative to each other and to placebo, for treating persistent ADHD in methadone-maintained patients. One hundred and twenty subjects, will be randomized to receive either MPH, BPR, or placebo with equal probability. Randomization will be stratified by site, and whether or not cocaine is also being used. Efficacy will be measured by treatment retention, reduction in illicit drug use and drug craving, improvement of ADHD symptoms and overall functional status.

Conditions

• ADHD
• Opioid-Related Disorders
• Cocaine Dependence

Interventions

Type	Name	Description
DRUG	Methylphenidate	Methylphenidate 80mg/day
DRUG	Bupropion	Bupropion 400mg/day
OTHER	Placebo	Placebo

Timeline

• Start date: 1998-02-01
• Primary completion: 2004-10-01
• Completion: 2004-10-01
• First posted: 2003-05-22
• Last updated: 2019-04-23

Locations

1 site across 1 country: United States