Trials / Unknown
UnknownNCT00495183
Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 108 (estimated)
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to assess the efficacy of caffeine compared to placebo as a maintenance treatment for cocaine dependence. Caffeine potentiation with biperiden will be also studied. Ninety patients with snorted/sniffed cocaine dependence will be randomized to receive caffeine (300 - 1200 mg t.i.d.) plus biperidene (8 mg b.i.d.) caffeine (300 - 1200 mg t.i.d.) with placebo or placebo during 10 days in an in-hospital setting.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | caffeine | caffeine from 300 to 1200 mg/d or 15 mg/kg/d, divided in 3 doses per day. |
| DRUG | Biperiden | Biperiden 2-4 mg/d, divided in 2 doses per day. |
| DRUG | Placebo | Placebo |
Timeline
- Start date
- 2009-01-01
- Primary completion
- 2010-07-01
- Completion
- 2010-07-01
- First posted
- 2007-07-02
- Last updated
- 2010-05-27
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT00495183. Inclusion in this directory is not an endorsement.