NCT01906346

Impact of a Non-Drug Choice on Cocaine Reinforcement

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: Joshua A. Lile, Ph.D. · Academic / Other
• Sex: All
• Age: 21 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate self-administration procedures and a non-drug alternative reinforcer, which is hypothesized to reduce the reinforcing effects of cocaine.

Conditions

• Cocaine Dependence

Interventions

Type	Name	Description
DRUG	Cocaine	Three active doses of cocaine will be made available for self-administration during experimental sessions.
DRUG	Placebo	Placebo cocaine will be made available for self-administration during experimental sessions.

Timeline

• Start date: 2014-01-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2013-07-24
• Last updated: 2019-05-17
• Results posted: 2019-05-17

Locations

1 site across 1 country: United States