NCT02416050

Predicting Relapse After Cocaine Inpatient Cessation

Prospective Prediction of Cocaine Relapse After Inpatient Cessation by Combining Functional Imaging and Neuropsychological Biomarkers With Craving and Impulsivity Measures

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 87 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Can brain MRI at entry of cocaine inpatient cessation attempt predict relapse during a three month follow-up ? Hypothesis : White matter losses in the prefrontal cortex are associated with relapse to cocaine use.

Detailed description

A multivariate model using MRI parameters, craving score, impulsivity score, and neuropsychological testing results will be tested to predict relapse or continuous abstinence three month after cocaine inpatient cessation attempt.

Conditions

• Cocaine Dependence
• Cocaine Use Disorder

Interventions

Type	Name	Description
PROCEDURE	Brain MRI imagery	Brain MRI performed during the first week of inpatient cocaine cessation

Timeline

• Start date: 2015-02-03
• Primary completion: 2022-01-03
• Completion: 2022-01-03
• First posted: 2015-04-14
• Last updated: 2023-03-13

Locations

1 site across 1 country: France