NCT00958282

Treatment of Cocaine Dependence With Lisdexamfetamine

Lisdexamfetamine Treatment for Cocaine Dependence

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This protocol is a 2-group double-blind placebo-controlled outpatient study investigating lisdexamfetamine for treatment of cocaine dependence. The investigators plan to enroll 100 subjects in a 14-week trial. The primary objectives will determine changes in cocaine use and secondary objectives will be cocaine craving and impulsivity.

Detailed description

This 2-group, double-blind, placebo-controlled, 14-week study (N=100) will investigate the efficacy of cognitive behavioral therapy plus lisdexamfetamine vs. placebo to treat cocaine dependence. We hypothesize that lisdexamfetamine will reduce cocaine use (primary outcome), as well as cocaine craving and impulsivity (secondary outcomes) vs. placebo.

Conditions

• Cocaine Dependence

Interventions

Type	Name	Description
DRUG	lisdexamfetamine/Behavior Therapy
OTHER	placebo

Timeline

• Start date: 2009-07-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2009-08-13
• Last updated: 2015-09-17
• Results posted: 2015-09-17

Locations

1 site across 1 country: United States