| Not Yet Recruiting | Cholinergic Enhancement of Theta NCT07228338 | University of Texas Southwestern Medical Center | EARLY_Phase 1 |
| Not Yet Recruiting | Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age Wit NCT06534502 | Azurity Pharmaceuticals | Phase 4 |
| Recruiting | The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy NCT07095933 | Xuanwu Hospital, Beijing | EARLY_Phase 1 |
| Not Yet Recruiting | Cenobamate in the Intensive Care Unit NCT06352723 | Brigham and Women's Hospital | EARLY_Phase 1 |
| Recruiting | Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up NCT07110454 | Epiminder America, Inc. | — |
| Not Yet Recruiting | Korus: a Device to Prevent Sudden Unexpected Death in Epilepsy (SUDEP) NCT06135285 | Brigham and Women's Hospital | N/A |
| Not Yet Recruiting | The Benefits of a Care Pathway Combining Remote Monitoring and Support From a Nurse After a Change in Anti-epi NCT07507240 | University Hospital, Toulouse | N/A |
| Not Yet Recruiting | Neural Basis of Cognition NCT05132543 | Duke University | N/A |
| Not Yet Recruiting | S100B Protein: a Diagnostic Aid in Episodes of Transient Loss of Consciousness? NCT07527754 | Assistance Publique - Hôpitaux de Paris | — |
| Not Yet Recruiting | TIS for Drug Resistant TLE NCT07519018 | Xijing Hospital | N/A |
| Not Yet Recruiting | A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome NCT07013331 | Hospices Civils de Lyon | N/A |
| Not Yet Recruiting | Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations NCT06898138 | Mayo Clinic | N/A |
| Not Yet Recruiting | Epileptiform Potential of Fully Immersive Virtual Reality NCT07451093 | Dartmouth-Hitchcock Medical Center | N/A |
| Not Yet Recruiting | Lily's Grace Temporal Interference NCT07520955 | University of Wisconsin, Madison | N/A |
| Not Yet Recruiting | Effect of Epilepsy and Antiepileptic Drug Therapy on Gastric Motility and Emptying With Point-Of-Care Gastric NCT07421661 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Recruiting | Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and O NCT07509190 | Anny Reyes | N/A |
| Not Yet Recruiting | MRgFUS for Childhood Epilepsy NCT07497178 | The Hospital for Sick Children | N/A |
| Not Yet Recruiting | Evaluation of the FYNA Research OPM MEG Device for Locating Epileptic Foci as Part of Pre-surgical Assessment NCT07281222 | Hospices Civils de Lyon | N/A |
| Not Yet Recruiting | Evaluation of the Efficacy of Neurofeedback Technique Based on EEG Desynchronization in Epileptic Patients NCT07356661 | Assistance Publique Hopitaux De Marseille | N/A |
| Not Yet Recruiting | Psychosocial Burden of Epilepsy NCT07449871 | Saglik Bilimleri Universitesi | — |
| Not Yet Recruiting | Health Literacy Project NCT06634901 | Duke University | N/A |
| Recruiting | AI-Based Mobile Intervention on Medication Non-Adherence and Transition NCT07445074 | University of Central Florida | N/A |
| Recruiting | Hippocampal Oscillations During Exploration NCT07224191 | NYU Langone Health | N/A |
| Not Yet Recruiting | Quality of Life Assessment in Patients With Epilepsy Using QOLIE-31 NCT07449845 | Saglik Bilimleri Universitesi | — |
| Not Yet Recruiting | Compassion Focussed Therapy Informed Psychoeducation and Loving Kindness Meditation for Young People With Epil NCT07265362 | University of Lincoln | N/A |
| Not Yet Recruiting | Prevalence of ADHD in Children With Epilepsy NCT07205211 | Assiut University | — |
| Not Yet Recruiting | Impact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory Reactivity NCT07249034 | Hospices Civils de Lyon | N/A |
| Not Yet Recruiting | Impact of Canine Mediation Practice in Psychomotor Therapy on Improving the Quality of Life in Adult Epileptic NCT06898749 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Not Yet Recruiting | Predictors of Drug Resistant Epilepsy Among Pediatric Patients NCT07241754 | Assiut University | — |
| Recruiting | Diagnosing Epilepsy To EffeCT Change NCT07110337 | Epiminder America, Inc. | N/A |
| Recruiting | LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome NCT07234695 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Phase 3 |
| Recruiting | A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures NCT07219407 | Rapport Therapeutics Inc. | Phase 2 |
| Not Yet Recruiting | The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis NCT07208656 | Cephas Health Research Initiative Inc, Ibadan, Nigeria | N/A |
| Recruiting | Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents NCT05126914 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disord NCT07329257 | University of Missouri-Columbia | — |
| Recruiting | LIFUS For Neurological Disorders NCT07417280 | University Health Network, Toronto | N/A |
| Not Yet Recruiting | Exploratory Study of UX-GIP001 Cell Therapy in Adult Patients With Drug-Resistant Unilateral Mesial Temporal L NCT07244328 | Second Affiliated Hospital, School of Medicine, Zhejiang University | EARLY_Phase 1 |
| Recruiting | National Survey on Physical and Sports Activity of Adults With Epilepsy NCT07075380 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Epilepsy and Driving NCT07026591 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Subcortical Arousal in Perceptual Awareness NCT06934356 | Yale University | N/A |
| Active Not Recruiting | BHV-7000 Responsive Neurostimulation System (RNS) Study NCT07125261 | Yale University | Phase 1 |
| Recruiting | Levetiracetam Three Times Daily in Epilepsy NCT07490769 | Waad Alkathiri | Phase 3 |
| Not Yet Recruiting | Prospective Evaluation of Probabilistic Predictions of Epileptic Seizure Risk Using the EPIDAY Tool NCT07068919 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Study to Evaluate the Relative Bioavailability of a New Formulation of NPT 2042 Soft-Gelatin Capsules Compared NCT07222878 | NeuroPro Therapeutics, Inc. | Phase 1 |
| Recruiting | Assessment of Kidney Function in Patients With Epilepsy NCT07288788 | Sohag University | — |
| Recruiting | Tianasen (ASO-GNAO1) for GNAO1-Encephalopathy With Epilepsy and Movement Disorders. NCT07363603 | Pirogov Russian National Research Medical University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Biomarker Targeted Stimulation for Epileptiform Events NCT06424977 | Cadence Neuroscience | N/A |
| Recruiting | Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG) NCT05944692 | CREmedical | — |
| Recruiting | Late-Onset Seizures: Trial of Vascular Risk Investigation and Treatment NCT07116330 | Sahlgrenska University Hospital | — |
| Not Yet Recruiting | Glioma Intraoperative MicroElectroCorticoGraphy NCT06408428 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Not Yet Recruiting | Multimodal PET Imaging With 18F-FDG/SV2A/TSPO for Resection Planning in Drug-Resistant Epilepsy NCT07147309 | Weibing Miao, PhD | — |
| Recruiting | Effect of Vagal Nerve Stimulation on Gastric Motor Functions NCT06038929 | Mayo Clinic | N/A |
| Recruiting | TAP-GRIN: Interventional Study on Patients With GRIN-related Neurodevelopmental Disorders NCT07377032 | Meyer Children's Hospital IRCCS | Phase 3 |
| Active Not Recruiting | Effect of Different Anesthetic Drugs on Electrocorticography (ECOG). NCT07165262 | Children's Cancer Hospital Egypt 57357 | Phase 3 |
| Not Yet Recruiting | Temporal Interference for Temporal Lobe Epilepsy Under SEEG NCT07082101 | Xijing Hospital | N/A |
| Recruiting | An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy NCT07509177 | Cynthia Kerson | N/A |
| Active Not Recruiting | Wearable Epileptic Seizure Prediction and Alert Glasses Based on Neuromorphic Computing NCT07139457 | Oman Ministry of Health | N/A |
| Recruiting | Bridging the Treatment Gap by Expanding Access to Care for People With Epilepsy in Kenya (BEACON) NCT06623994 | Indiana University | N/A |
| Recruiting | Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application NCT06425029 | Dartmouth-Hitchcock Medical Center | N/A |
| Recruiting | Effect of Vitamin D3 Supplementation on Brain Waves in Male Epileptic Patients With Hypovitaminosis D NCT07096414 | Bangladesh Medical University | N/A |
| Not Yet Recruiting | NYU Epilepsy Self-Management Study NCT07087821 | NYU Langone Health | N/A |
| Recruiting | Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Epileptic Patients With Hypov NCT07085598 | Bangladesh Medical University | N/A |
| Recruiting | Effect of Rose Odor Exposure on Ictal Apnea NCT07116421 | Vanderbilt University Medical Center | EARLY_Phase 1 |
| Recruiting | Sleep and Rehearsal-Driven Memory in Epilepsy NCT06967935 | Hospices Civils de Lyon | — |
| Recruiting | Seizure Prediction Using Wearable EEG NCT06978842 | Dux Healthcare Inc. | — |
| Recruiting | Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in H NCT07051629 | Suninflam Inc | Phase 1 |
| Completed | Massage Based on the Human Caring Model in Epilepsy NCT07000591 | Muş Alparslan University | N/A |
| Not Yet Recruiting | Lacosamide Intravenous Injection for Emergency Termination of Status Epilepticus NCT06966830 | Second Affiliated Hospital of Guangzhou Medical University | — |
| Completed | Bioavailability of Stiripentol After Single Oral Dose of Capsule vs Suspension in Healthy Subjects (STILIQ) NCT07176832 | Biocodex | Phase 1 |
| Not Yet Recruiting | Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases NCT07009990 | University Medicine Greifswald | — |
| Recruiting | Registry and Natural History of Epilepsy-Dyskinesia Syndromes NCT06967727 | Boston Children's Hospital | — |
| Recruiting | Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resi NCT07202494 | Assistance Publique Hopitaux De Marseille | — |
| Recruiting | SeizEAR Safety Study NCT07088835 | Icahn School of Medicine at Mount Sinai | N/A |
| Not Yet Recruiting | The Effect of Memory-Based Exercise and Planned Training Applied to Epilepsy Patients on Quality of Life NCT06954922 | Ataturk University | N/A |
| Recruiting | Invasive Brain-Computer Interfaces for Attention NCT06940089 | University of Texas at Austin | N/A |
| Not Yet Recruiting | Prevalence and Pattern of Headache in Pediatric Epilepsy NCT06868251 | Assiut University | — |
| Active Not Recruiting | A Study of the Effectiveness of Risk Minimization Measures Related to Depakine® (Sodium Valproate) in Saudi Ar NCT06714448 | Sanofi | — |
| Recruiting | Ear-Seizure Detection (EarSD) Study NCT06598189 | Felicia Chu | N/A |
| Recruiting | Implementation and Cost Evaluation of Project UPLIFT NCT06865820 | Emory University | N/A |
| Recruiting | Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy NCT05527093 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Effect of the EpiSchool-M App on Teachers' Epilepsy Knowledge, Attitudes, and Self-Management NCT06807047 | Kafkas University | N/A |
| Active Not Recruiting | This Study Will Assess the Etiology, Potential Risk Factors, and Seizure Types in Patients Over 50 With Epilep NCT07026409 | Sohag University | — |
| Not Yet Recruiting | Sensory Modulation in Children With Epilepsy NCT06818344 | Abant Izzet Baysal University | — |
| Recruiting | High-field MR Imaging in Migraine, Visual Snow and Epilepsy NCT05524493 | University of Zurich | — |
| Not Yet Recruiting | Sensory Perception in Children With Epilepsy NCT06818357 | Abant Izzet Baysal University | — |
| Recruiting | Spatial Memory and Temporal Lobe Epilepsy NCT06847152 | Centre Hospitalier Metropole Savoie | N/A |
| Recruiting | Effects of Mega-dose Vitamin D Pulse and Maintenance Therapy on Seizure Frequency, Fatigue, and Quality of Lif NCT06736002 | Chin-Wei Huang | N/A |
| Not Yet Recruiting | Evaluation of the Incidence of Psychiatric Disorders As a Function of First-line Antiepileptic Drug Prescribin NCT06829693 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings NCT06883981 | University of Utah | N/A |
| Recruiting | Evaluating Modulation Effects of Burst Stimulation Patterns Using SEEG NCT06667232 | Xuanwu Hospital, Beijing | N/A |
| Not Yet Recruiting | Effects of Exercise on Functional Performance, BDNF, Executive Functions and Sleep Quality in Children with Ep NCT06677034 | Inonu University | N/A |
| Recruiting | Self-management Intervention for Reducing Epilepsy Burden Among Ugandans With Epilepsy. NCT06139198 | Makerere University | N/A |
| Not Yet Recruiting | A Retrospective Study to Validate BioEP as an Assessment Aid for Seizure Susceptibility NCT06669364 | Neuronostics Ltd | — |
| Not Yet Recruiting | OASIS: RetrOspective Analysis on EEGs for Identifying Seizure Susceptibility in paediatrIcs Using biomarkerS NCT06546410 | Neuronostics Ltd | — |
| Recruiting | Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surger NCT06280092 | Sanjeet S. Grewal | EARLY_Phase 1 |
| Recruiting | Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder NCT06695767 | The University of Texas Health Science Center, Houston | N/A |
| Recruiting | Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epilepti NCT06334952 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Efficacy of Low Glycemic Index Diet Versus Classic Ketogenic Diet in Pediatric Epilepsy Treatment NCT06703983 | Mashhad University of Medical Sciences | N/A |
| Not Yet Recruiting | Clinical Utility and Safety of Human Umbilical Cord Mesenchymal Stem Cell Secretome in Drug Resistant Epilepsy NCT06638970 | Baermed | Phase 1 |
| Completed | Pro-Epileptic Effects of IV Ketamine NCT06741930 | Haseki Training and Research Hospital | Phase 4 |
| Completed | Effects of Podcast Education on Medication Perception, Stigma Level, and Epilepsy Self-management in Epilepsy NCT07090980 | Istanbul Sabahattin Zaim University | N/A |
| Recruiting | Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Ep NCT02531880 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 |
| Recruiting | Clinic-based and Technology-Supported Sleep Intervention for Pediatric Epilepsy NCT06661759 | National Taiwan University Hospital | N/A |
| Completed | Investigation of the Effects of Pilates Training in Patients With Drug-Resistant Epilepsy NCT06754124 | Recep Tayyip Erdogan University Training and Research Hospital | N/A |
| Completed | A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning (USF) NCT06705439 | Neuro Event Labs Inc. | — |
| Recruiting | Caracterization of the Combined Alterations in Respiration and aROUSal in Patients With Drug-resistant EpiLeps NCT06545214 | Hospices Civils de Lyon | N/A |
| Active Not Recruiting | Characterization of Neurocognitive Profiles in Neurodevelopmental Disorders and Epilepsy: a Transdiagnostic Ap NCT06877260 | IRCCS Eugenio Medea | — |
| Not Yet Recruiting | Effects of Levetiracetam Monotherapy on Various Hematological Parameters in Adult Patients Suffering of Epilep NCT06491303 | Assiut University | — |
| Recruiting | Lemborexant Treatment of Insomnia Linked to Epilepsy NCT06262594 | University of Manitoba | Phase 3 |
| Recruiting | Taiwan Post-Stroke Disability Study NCT06772194 | National Taiwan University Hospital | — |
| Recruiting | PHArmacotherapy Assessed Using Neuroprobing With TransOsseal Magnetic Stimulation NCT06892457 | Insel Gruppe AG, University Hospital Bern | — |
| Active Not Recruiting | Ultra-long-term EEG Monitoring in PwID NCT07385157 | University of Plymouth | — |
| Recruiting | Effect of Cognitive Behavioral Play Intervention and Epilepsy NCT06813612 | IRCCS National Neurological Institute "C. Mondino" Foundation | N/A |
| Enrolling By Invitation | Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet NCT06369571 | Johns Hopkins University | Phase 1 / Phase 2 |
| Recruiting | Magnetoencephalography in Children NCT06668519 | Children's Hospital of Fudan University | — |
| Recruiting | A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patien NCT06388707 | NaviFUS Corporation | Phase 1 / Phase 2 |
| Recruiting | Neuropsychiatric Research Databases for People With Intellectual Disabilities and Epilepsy (REFINE) NCT06780501 | University of Plymouth | — |
| Not Yet Recruiting | iMRI Prone Positioning Frame Design Feasibility Study NCT06388512 | University of Kansas Medical Center | N/A |
| Recruiting | A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients Wi NCT06492720 | NaviFUS Corporation | N/A |
| Withdrawn | Epilepsy Self-Management for Spanish Speakers: HOBSCOTCH - ESPANOL NCT06462911 | Dartmouth-Hitchcock Medical Center | N/A |
| Not Yet Recruiting | A Study to Assess utiLity of BIoEP as an Early Prognostic Indicator for Predicting Anti-Seizure Medication (AS NCT06354868 | Neuronostics Ltd | — |
| Enrolling By Invitation | Human Thalamus in Propagation of Temporal Lobe Seizures and Memory Formation NCT07226908 | Stanford University | N/A |
| Completed | A Double Blind, Randomized, Cross-over Study Examining the Suppression of the Photoparoxysmal EEG Response Wit NCT06525649 | NeuroPro Therapeutics, Inc. | Phase 1 |
| Recruiting | MiCrobiota-gut-brain Axis in Resistant Epilepsy NCT07010445 | Niguarda Hospital | N/A |
| Not Yet Recruiting | High Selective Subiculum SEEG Guided RF-TC for mTLE-HS NCT06558864 | Xuanwu Hospital, Beijing | N/A |
| Completed | Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders NCT06412653 | Children's University Hospital Cologne, Germany | Phase 2 |
| Completed | Comparison of Oral Brivaracetam Versus Levetiracetam as Monotherapy in Epilepsy NCT07163585 | RESnTEC, Institute of Research | N/A |
| Not Yet Recruiting | Healthy Aging in People With Epilepsy Program NCT06052605 | University of California, San Diego | N/A |
| Not Yet Recruiting | Effect of Adding Lamotrigine to Sodium Valproate in Childhood Epilepsy: Clinicolabratory Study NCT05881928 | Assiut University | Phase 4 |
| Completed | The Effect of Dual Task on Postural Control in Children Diagnosed with Epilepsy NCT06529133 | Bezmialem Vakif University | N/A |
| Recruiting | Prediction of Anxiety and Memory State NCT06551090 | Columbia University | N/A |
| Completed | A Novel Social Emotional Learning Curriculum for Youth With Epilepsy NCT06427967 | Boston Medical Center | N/A |
| Enrolling By Invitation | Causal Role of Top-Down Theta Oscillations in Prioritization NCT06252532 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy- NCT06585605 | Boston Children's Hospital | — |
| Completed | Safety and Efficacy of tPBM for Epileptiform Activity in Autism NCT06352372 | Richard Frye | Phase 2 |
| Recruiting | Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy NCT06210022 | IRCCS San Raffaele | — |
| Completed | Evaluating the Efficacy of a Mobile Epilepsy Education Application NCT06402526 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Completed | Evaluating the Impact of Virtual Reality Exposure Therapy on Epilepsy/Seizure-Specific Interictal Anxiety NCT06028945 | University Health Network, Toronto | N/A |
| Recruiting | The Clinical Utility of BioEP in Diagnostic Decision Making in Epilepsy NCT06097195 | Neuronostics Ltd | N/A |
| Enrolling By Invitation | Neuronal and Network Mechanisms of Electrocortical Stimulation NCT06391294 | Northwestern University | N/A |
| Enrolling By Invitation | The Effect of a Computer-Assisted Rehabilitation Program on Epilepsy Patient NCT06376370 | Selcuk University | N/A |
| Recruiting | Risk Prevention Program and Therapeutic Patient Education Program of Patients With Uncontrolled Epilepsy NCT06202196 | University Hospital, Montpellier | N/A |
| Not Yet Recruiting | Assessment of Patients With Drug-resistant Temporal Lobe Epilepsy With EEG Extended With Intra-auricular Elect NCT06366009 | Przemyslaw Kunert | — |
| Withdrawn | Neurodevelopmental Effects of Antiseizure Medications (NEAM) - UG3 Phase NCT05364853 | Stanford University | N/A |
| Recruiting | Microelectrode Recordings From the Vagus Nerve in Awake Humans NCT06016686 | University of Minnesota | Phase 1 |
| Recruiting | Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care NCT06346262 | University Hospitals Cleveland Medical Center | Phase 4 |
| Unknown | The Effect of Web-based Education Provided According to the Health Promotion Model on Self - Management in Epi NCT06194916 | Ataturk University | N/A |
| Not Yet Recruiting | Impact of a Community Based Engagement Program Focused on Adolescents With Epilepsy NCT05660239 | Makerere University | N/A |
| Enrolling By Invitation | International Post-Stroke Epilepsy Research Repository NCT06108102 | Yale University | — |
| Recruiting | The Value of EEG in Stroke Units NCT07190976 | Attikon Hospital | — |
| Completed | Cognitive Function and Glymphatic System in Children with Epilepsy NCT06143241 | Ege University | N/A |
| Recruiting | EPIGUT: EPILEPSY AND GASTROINTESTINAL MICROBIOTA: UNDERSTANDING THERAPY RESPONSE NCT07253701 | Karolinska Institutet | — |
| Recruiting | Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With Epilepsy NCT06353620 | IRCCS Eugenio Medea | — |
| Recruiting | Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement NCT06241924 | University Hospital, Bordeaux | N/A |
| Recruiting | Identification of Volatile Organic Compounds (VOCs) as Biopredictors of Epileptic Seizures NCT05865561 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Patterns of Neurodevelopmental Disorders NCT06213090 | Richard Frye | — |
| Unknown | First-in-human Experience Using Novel Ultraflexible Low-impedance Electrode Arrays: an IDEAL Stage 1 Study NCT06116279 | Great Ormond Street Hospital for Children NHS Foundation Trust | N/A |
| Recruiting | Contribution of Fast-ripples to the Improvement of the Neurosurgical Management of Drug-refractory Epilepsy NCT06105645 | University Hospital, Toulouse | N/A |
| Completed | Brain Regions and Functional Neuronal Network Characteristics of Dexmedetomidine Analgesia NCT05500703 | China International Neuroscience Institution | Phase 4 |
| Unknown | Exploring Patient Impact & Value in Epilepsy Wearables for Seizure Monitoring NCT06180538 | Royal College of Surgeons, Ireland | — |
| Terminated | DigitalEPI - A Prospective Pilot Study NCT05739669 | Karl Landsteiner Institute for Clinical Epilepsy Research and Cognitive Neurology | N/A |
| Withdrawn | Cardiovascular Risk Reduction in Epilepsy NCT05704439 | University of California, Los Angeles | N/A |
| Unknown | Low-Glycemic (LGI) Diet in Pregnant People With Epilepsy NCT06175247 | Brigham and Women's Hospital | N/A |
| Recruiting | RESEARCH EVALUATING VAGAL EXCITATION AND ANATOMICAL LINKS NCT06143293 | University of Minnesota | N/A |
| Recruiting | Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders NCT04322734 | Southwest Autism Research & Resource Center | — |
| Recruiting | Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery NCT05992402 | Kayela Arrotta | N/A |
| Recruiting | Electrical Impedance Tomography & Selective Stimulation of Vagus Nerve NCT05664854 | University College, London | N/A |
| Active Not Recruiting | U011 - Wireless Ultra Long-Term EEG Recordings in Epilepsy NCT05915988 | UNEEG Medical A/S | N/A |
| Active Not Recruiting | Precision Radiation Treatment for Epilepsy (PRECISION) NCT05182437 | Maastricht Radiation Oncology | N/A |
| Recruiting | Optimized and Personalized Trans-cranial Brain Stimulation in Partial Refractory Epilepsies NCT06212609 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | SCN2A Polymorphisms Are Associated With Response to Valproic Acid in Paediatric Population(Pakistan) NCT06674070 | Riphah International University | — |
| Recruiting | Behavioral and Neuronal Correlates of Human Mood States NCT06159595 | Stanford University | N/A |
| Unknown | Comparison of Quality of Life and Changes Experienced by Patients After Epilepsy Surgery NCT06035965 | University Hospital, Toulouse | — |
| Unknown | Transcranial Magnetic Stimulation (TMS) in Genetic Epilepsies NCT06284291 | Meyer Children's Hospital IRCCS | N/A |
| Completed | Bioequivalence Study of Perampanel Tablets 10 mg NCT06450236 | Humanis Saglık Anonim Sirketi | Phase 1 |
| Recruiting | Real World Evidence on the Use of Medical Cannabis in Pediatrics NCT05863910 | University of Manitoba | — |
| Recruiting | SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom NCT06504511 | NHS Greater Glasgow and Clyde | — |
| Recruiting | MEHMO Natural History and Biomarkers NCT06019182 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | — |
| Recruiting | Impact of Capturing Ictal Events With Ultra-long-term Ambulatory EEG Monitoring With Remote EEG Monitoring Sys NCT06027749 | Epitel, Inc. | N/A |
| Active Not Recruiting | Rehabilitation of Cognition and Psychosocial Well-being in Epilepsy NCT05934786 | Vilnius University | N/A |
| Completed | Impact of Pharmacist-led Cognitive Behavioral Intervention on Adherence and Quality of Life of Epileptic Patie NCT06034353 | Hamdard University | N/A |
| Recruiting | PET/MRI/EEG Imaging Study in Epilepsy NCT06974305 | Massachusetts General Hospital | — |
| Completed | Tools for Anxiety and Depression Screening in Epilepsy NCT05864612 | Wake Forest University Health Sciences | N/A |
| Recruiting | Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy) NCT05954182 | Kayela Arrotta | N/A |
| Completed | Bioequivalence Study of Perampanel Tablets 12 mg NCT06450223 | Humanis Saglık Anonim Sirketi | Phase 1 |
| Completed | Evaluation of Levetiracetam's Effectiveness and Tolerability for Treating Epilepsy in Older Adults NCT07422233 | Nasim Tabrizi | Phase 4 |
| Recruiting | Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysi NCT05996900 | Stanford University | N/A |
| Active Not Recruiting | A Prospective Diagnostic Belief Updating Study to verIfy the Utility of BioEP in First Seizure Clinics. NCT05764252 | Neuronostics Ltd | — |
| Completed | Reflexology on Seizure Frequency, Fatigue, Stress and Sleep Quality in Epilepsy Patients NCT06120101 | Ataturk University | N/A |
| Recruiting | Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits NCT04419272 | VA Office of Research and Development | Phase 4 |
| Unknown | Bioequivalence Study of Sodium Valproate and Valproic Acid Tablets NCT05641649 | Kathmandu University | Phase 4 |
| Recruiting | Neural Autoantibody Prevalence in New-onset Focal Seizures of Unknown Etiology NCT06388161 | Shen Chun-Hong | — |
| Recruiting | Seizure Recurrence After Unprovoked First Seizure NCT05724719 | Dr. Gavin Winston | — |
| Completed | IF-MCT 16:8: Investigating the Influence of Intermittent Fasting With and Without MCTs in Patients With Drug-r NCT06013761 | University Hospital Marburg | N/A |
| Unknown | Real World Testing and Cost-effectiveness Analysis of Subcutaneous EEG NCT06144047 | King's College London | N/A |
| Unknown | Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy NCT05969054 | Xiangya Hospital of Central South University | Phase 4 |
| Recruiting | Intracranial Investigation of Neural Circuity Underlying Human Mood NCT05871372 | Baylor College of Medicine | N/A |
| Withdrawn | Assessment of Effect of Vagal Nerve Stimulator (VNS) on Electrocorticograms Recorded by Responsive Neurostimul NCT03595072 | University of Colorado, Denver | — |
| Unknown | The Living With a Long-Term Condition Study NCT06072287 | King's College London | — |
| Recruiting | Observational Study of the Structural-functional Connectome in Patients With Epilepsy NCT06334029 | IRCCS Eugenio Medea | — |
| Completed | Development of a Seizure Detection Algorithm Based on Heart Rate and Movement Analysis NCT05637762 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Completed | Children's Adaptive Deep Brain Stimulation for Epilepsy Trial (CADET): Pilot NCT05437393 | University College, London | N/A |
| Withdrawn | Energy Expenditure and Quality of Life in Epilepsy NCT04546711 | University of Wisconsin, Madison | — |
| Active Not Recruiting | The Effect of Sleep Hygiene Given to Epilepsy Patients on Seizure Frequency and Sleep Quality NCT06352476 | Marmara University | N/A |
| Unknown | Cannabidiol in Children and Young Adults With Rare Disease-associated Severe Epilepsy NCT05803434 | Meyer Children's Hospital IRCCS | Phase 2 |
| Recruiting | Idiopathic Generalized Epilepsy Cognitive and Emotional Profile NCT06782074 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Recruiting | Transition From Pediatric to Adult Epilepsy Care NCT06778772 | IRCCS National Neurological Institute "C. Mondino" Foundation | — |
| Unknown | Music as an Adjunctive Epileptic Seizure Treatment Option NCT05545540 | University of Aberdeen | N/A |
| Unknown | Onchocerciasis-Associated Epilepsy, an Explorative Case-control Study NCT05868551 | Universiteit Antwerpen | — |
| Recruiting | Predisposing Factors for Post-stroke Epilepsy NCT05864547 | Norwegian University of Science and Technology | — |
| Recruiting | Collaborative Care for Anxiety and Depression in Epilepsy NCT05559749 | Wake Forest University Health Sciences | N/A |
| Active Not Recruiting | Adjunctive Anti-seizure Medication (ASM) Real World Evidence (RWE) Study NCT05867160 | Aziende Chimiche Riunite Angelini Francesco S.p.A | — |
| Unknown | Electrical Neuromodulation for Focal Epilepsy NCT05844696 | National Taiwan University Hospital | Phase 1 / Phase 2 |
| Recruiting | An Observational Study of Epilepsy: Biology and Outcomes Using Real-world Data NCT05632978 | Cardiff and Vale University Health Board | — |
| Recruiting | Effects of Recorded Music on Clinical and EEG Seizure Activity NCT05289934 | Johns Hopkins University | N/A |
| Recruiting | A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Ence NCT05737784 | Praxis Precision Medicines | Phase 1 / Phase 2 |
| Recruiting | Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue) NCT06053671 | King's College Hospital NHS Trust | N/A |
| Recruiting | Effects of Social Feedback on Intracranial EEG NCT06975800 | Trustees of Dartmouth College | N/A |
| Unknown | An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparati NCT05788159 | Overseas Pharmaceuticals, Ltd. | Phase 1 |
| Recruiting | Intensive Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy NCT05609084 | Assistance Publique Hopitaux De Marseille | N/A |
| Recruiting | Hybrid Micro-macro Electrodes in Patients with Epilepsy NCT05335187 | Pierre Mégevand | N/A |
| Completed | Pilot to Evaluate VR-Therapy on People With Epilepsy and Related Anxiety NCT05296057 | University Health Network, Toronto | N/A |
| Unknown | Implicit Learning in Epileptic Children NCT05285059 | Hospices Civils de Lyon | — |
| Recruiting | Remote Neuropsychological Assessment of Patients With Neurological Disorders and Injuries NCT05819008 | Umeå University | — |
| Unknown | Assessment of Remote EEG Monitoring (REMI-EEG) in Pediatric Emergency and Adult Critical Care Units NCT05818930 | Epitel, Inc. | N/A |
| Recruiting | Stimulation-Induced Changes in Fronto-Limbic Network NCT05854160 | University of Alabama at Birmingham | N/A |
| Completed | Formative Validation of the MoveChecker System NCT05824611 | Gaia AG | — |
| Completed | How Would the Creation of a Follow-up Methodology in Consultation Improve the Care of the Epileptic Patient? NCT05741541 | Hopital Nord Franche-Comte | — |
| Completed | Steps for Epilepsy NCT05359003 | Wake Forest University Health Sciences | N/A |
| Completed | Coenzyme Q10 as Adjunctive Therapy in Drug-Resistant Epilepsy NCT07537283 | National Cheng-Kung University Hospital | N/A |
| Completed | EPIDREAM 1 : Study of Dreaming in Epilepsy NCT05561166 | Hospices Civils de Lyon | — |
| Unknown | Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy NCT05518578 | Supernus Pharmaceuticals, Inc. | Phase 2 |
| Recruiting | Volatile Non-Invasive Biomarkers of Epileptic Seizures NCT05725174 | University College London Hospitals | — |
| Completed | This is a Retrospective Study on the Use of CENOBAMATE as Adjunctive Treatment in Patients Suffering From Epil NCT05747001 | Aziende Chimiche Riunite Angelini Francesco S.p.A | — |
| Active Not Recruiting | Cenobamate in Adults With Focal-Onset Seizures NCT05859854 | Aziende Chimiche Riunite Angelini Francesco S.p.A | — |
| Recruiting | The Lullaby Project as a Musical Intervention for Pregnant Individuals With Epilepsy NCT05503290 | University Health Network, Toronto | N/A |
| Withdrawn | EpiCare@Home Validation Study for Focal Onset Seizures NCT05738226 | Byteflies | N/A |
| Recruiting | Human Intracranial Electrophysiology NCT05529264 | Dartmouth-Hitchcock Medical Center | N/A |
| Withdrawn | Thalamic Stimulation for Epilepsy Study NCT04102254 | Duke University | N/A |
| Recruiting | Brain Representation of Acquisition in Humans of Motor-Sensory Skills NCT05688683 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Idiopathic Generalized Epilepsy Syndromes NCT06388174 | Shen Chun-Hong | — |
| Unknown | Study The Knowledge and Attitude Towards Epilepsy Among Relatives of People With Epilepsy and Their Impact on NCT05671575 | Mohamed Adel Abdellah | — |
| Recruiting | Clinical Study Evaluating Safety of Pentoxifylline and Celecoxib in Patients With Grand-Mal Epilepsy Treated b NCT05637086 | Mostafa Bahaa | Phase 2 |
| Recruiting | Pharmacogenetics-Based Study on Individualized Use of Sodium Valproate NCT07046676 | The First Affiliated Hospital of University of South China | Phase 4 |
| Completed | Impact of COVID-19 Pandemic on Epilepsy Evaluations in the Pediatric Emergency Department NCT06294977 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | — |
| Completed | Systematic Evaluation of VNS Parameters NCT05395026 | Duke University | N/A |
| Unknown | Adjunctive Everolimus Treatment of Refractory Epilepsy NCT05613166 | National Institute on Drug Dependence, China | Phase 2 |
| Active Not Recruiting | Neuroliten MVP System Clinical Observation Study NCT05520476 | Enliten AI | — |
| Completed | Safety and Pharmacokinetic Study of NPT 2042 Soft-gelatin Capsules Administered Orally to Healthy Adult Subjec NCT05503511 | NeuroPro Therapeutics, Inc. | Phase 1 |
| Completed | A Study to Evaluate the Efficacy and Safety of Perampanel Monotherapy in Untreated Participants With Focal Ons NCT05533814 | Eisai Korea Inc. | Phase 4 |
| Completed | Metformin Efficacy and Safety in Epileptic Patients NCT05722951 | Tanta University | Phase 3 |
| Active Not Recruiting | Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome NCT05472389 | Hospices Civils de Lyon | N/A |
| Active Not Recruiting | RNS System LGS Feasibility Study NCT05339126 | NeuroPace | Phase 2 |
| Recruiting | Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease NCT06092125 | Xuanwu Hospital, Beijing | — |
| Enrolling By Invitation | Testing a Novel Dry Electrode Headset for Electroencephalography Telehealth NCT05380921 | VA Office of Research and Development | N/A |
| Unknown | Bridging Gaps in the Neuroimaging Puzzle: New Ways to Image Brain Anatomy and Function in Health and Disease U NCT05769933 | CSEM Centre Suisse d'Electronique et de Microtechnique SA - Recherche et Developpement | — |
| Completed | Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy: A Case Study NCT05325047 | Assistance Publique Hopitaux De Marseille | N/A |
| Completed | Self Acupressure on Fatigue and Sleep Quality in Epilepsy Patients NCT05552924 | Ataturk University | N/A |
| Unknown | Comorbidities of Epilepsy(Cognitive and Psychiatric Dysfunction) NCT05559060 | Assiut University | — |
| Completed | Effectiveness of an Epilepsy Application for Self-management in Viet Nam NCT05491369 | University of Medicine and Pharmacy at Ho Chi Minh City | N/A |
| Unknown | Integrating a Mental Health Intervention Into Primary Health Care for Refugees NCT05512624 | International Rescue Committee | N/A |
| Unknown | Sodium-Glucose Cotransporter-2 Inhibitors: A Potential Novel Treatment for Epilepsy NCT05512130 | Washington University School of Medicine | EARLY_Phase 1 |
| Enrolling By Invitation | Functional Organization of the Superior Temporal Gyrus for Speech Perception NCT05435859 | University of California, San Francisco | N/A |
| Active Not Recruiting | Neonatal Seizure Registry, GEnetics of Post-Neonatal Epilepsy NCT05361070 | University of California, San Francisco | — |
| Active Not Recruiting | RNS System NAUTILUS Study NCT05147571 | NeuroPace | Phase 3 |
| Unknown | Cortical Excitability in Post-traumatic Epilepsy NCT05517954 | Mid-Atlantic Epilepsy and Sleep Center, LLC | — |
| Recruiting | Mapping of Human Cognition NCT05989893 | The University of Texas Health Science Center, Houston | N/A |
| Completed | A Study of Detection of Paroxysmal Events Utilizing Computer Vision and Machine Learning - Nelli NCT05606575 | Neuro Event Labs Inc. | — |
| Recruiting | Clinical Outcomes of Pregnant Individuals With Epilepsy - Prospective Study NCT05485649 | University Health Network, Toronto | — |
| Recruiting | Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding NCT05450978 | University of Pittsburgh | — |
| Unknown | Comparison of the Electric Plasma Surgical Tool "PlasmaBlade" for Replacement of the Deep Brain Stimulation (D NCT05535556 | Yonsei University | — |
| Unknown | Clinical Evaluation of Interstitial Laser Thermal Therapy Under Continuous MRI Monitoring as a Minimally Invas NCT05198882 | Assistance Publique - Hôpitaux de Paris | Phase 1 |
| Unknown | The Role of Intracranial Electroencephalography (IEEG) in the Localization of Epileptogenic Zones (EZ) and Its NCT05443958 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Enrolling By Invitation | Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation NCT05450237 | Neuromed IRCCS | — |
| Unknown | Possible Immuno-Modulatory Effect of Tocilizumab in Patients With Refractory Status Epilepticus. NCT05346666 | Damanhour University | Phase 3 |
| Completed | The Effect of Cognitive Rehabilitation on Epileptic Pateints Under Treatment NCT06643559 | Gulhane Training and Research Hospital | N/A |
| Recruiting | Intracranial Stimulation Mapping In Epilepsy NCT05290610 | University of Minnesota | N/A |
| Completed | Risk Factors and Etiologies of Epilepsy in Urban and Rural Rwanda NCT05698537 | University Hospital, Ghent | — |
| Unknown | Connectivity Alterations After Levetiracetam Application NCT04425798 | Beijing Neurosurgical Institute | — |
| Completed | Sodium Lactate Infusion in GLUT1DS Patients NCT04112862 | Radboud University Medical Center | EARLY_Phase 1 |
| Recruiting | Functional Brain Mapping for Patients with Epilepsy NCT05755919 | Wayne State University | N/A |
| Completed | A Study on Telemedicine Applied to Actual Outpatient Clinic for Epilepsy NCT05418257 | Samsung Medical Center | — |
| Unknown | Assessment of Adults Epidemiological Characteristics of Status Epilepticus in the French West Indies and in Fr NCT05246566 | University Hospital Center of Martinique | — |
| Recruiting | Brain Metabolism Observed at 7 Tesla NCT05085704 | University of Texas Southwestern Medical Center | — |
| Completed | Flexible Representation of Speech NCT05209386 | University of Pittsburgh | N/A |
| Unknown | Evaluation Of A Mobile Messaging Service In Improving Adherence Of Anti-Seizure Medications NCT05321641 | KEMRI-Wellcome Trust Collaborative Research Program | N/A |
| Recruiting | EPC Performance Investigation for StereoElectroEncephaloGraphy NCT05223985 | Alcis | — |
| Completed | Evaluation of Direct Effects of Electric Fields on Brain NCT05250713 | Assistance Publique Hopitaux De Marseille | N/A |
| Terminated | Safety, Tolerability, and Efficacy of RLS103 in a Clinical Model of Photosensitive Epilepsy NCT05678881 | Receptor Life Sciences | Phase 1 |
| Completed | A Prospective, Remote Observational Study in Pediatric Participants With Early-Onset SCN2A-Developmental and E NCT05407727 | Praxis Precision Medicines | — |
| Completed | Epidiolex® for Anxiety in Pediatric Epilepsy NCT05324449 | Hugo W. Moser Research Institute at Kennedy Krieger, Inc. | Phase 4 |
| Unknown | Study on the Population Pharmacokinetics of Levetiracetam in Epileptic Patients With Diabetic Kidney Disease NCT05330390 | The Second Hospital of Shandong University | — |
| Completed | Protective Role of Pre-/ Post-biotics on Gut Inflammation, Dysbiosis, and Life Quality in Rett Syndrome (Bioti NCT05420805 | Azienda Ospedaliera Universitaria Senese | N/A |
| Recruiting | Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing NCT05418894 | Baylor College of Medicine | N/A |
| Unknown | Study of Speech Function in Epileptic Patients Based on Stereoelectroencephalography Signal NCT05776745 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Cortical Excitability and Treatment Response in People with Epilepsy NCT05551403 | Stichting Epilepsie Instellingen Nederland | N/A |
| Unknown | Validation of an Italian Questionnaire of Adherence to the Ketogenic Diet NCT05377762 | University of Pavia | — |
| Unknown | Lacosamide in Neonatal Status Epilepticus NCT05291455 | Sherief Abd-Elsalam | Phase 3 |
| Completed | Air Polishing Effect on Biological, Clinical and Patient-reported Experience Among Epileptic and Non-epileptic NCT06144034 | King Abdullah University Hospital | N/A |
| Recruiting | A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in China NCT05638269 | Zhujiang Hospital | — |