Trials / Recruiting
RecruitingNCT06892457
PHArmacotherapy Assessed Using Neuroprobing With TransOsseal Magnetic Stimulation
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Insel Gruppe AG, University Hospital Bern · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this observational study is to investigate how prescribed anti-seizure medications (ASMs) affect cortical excitability in adults with epilepsy. The main questions it aims to answer are: 1. Does the magnitude of transcranial magnetic stimulation (TMS)-evoked potentials (TEPs) measured with electroencephalography (EEG) change between OFF and ON medication states? 2. Do these changes in TEP amplitude persist over time? Researchers will compare each participant's measurements in the OFF state with those in the ON state to see if TEPs change following ASM (re)start. Participants will undergo one TMS-EEG session scheduled around their prescribed ASM (re)start and one 1-6 months later.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | TMS-EEG | Evoked brain activity is measured with the help of TMS-EEG in epilepsy patients OFF and ON medication. |
Timeline
- Start date
- 2024-10-21
- Primary completion
- 2029-10-01
- Completion
- 2029-10-01
- First posted
- 2025-03-24
- Last updated
- 2025-03-24
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT06892457. Inclusion in this directory is not an endorsement.