NCT06035965

Comparison of Quality of Life and Changes Experienced by Patients After Epilepsy Surgery

Comparison of Quality of Life and Changes Experienced by Patients After Epilepsy Surgery, With Long-term Epileptological Objective Results

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 160 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 15 Years
• Healthy volunteers: Not accepted

Summary

Epilepsy is one of the most common chronic neurological diseases. According to data from the World Health Organization (WHO), it affects 0.5 to 1% of the population, or around 70 million people world-wide and around 600,000 in France. There are several more or less severe forms of epilepsy depending on the type of epileptic seizures and the frequency of these seizures. About 30% of epileptic patients respond poorly to well-conducted medical treatment, which makes the number of so-called "drug-resistant" patients estimated at between 100,000 and 150,000 patients. Epilepsy surgery is possible in some cases of drug-resistant epilepsy and can lead to complete seizure control. Beyond the impact on the control of seizures, surgery can have an impact on the lives of patients at the psychological, emotional and cognitive level, with consequences on their socio-professional but also personal life. Thus the impact on the daily life of patients after epilepsy surgery can vary greatly from one patient to another and the personal feelings of operated patients do not always seem to correspond to the objective elements collected by doctors. 2.3 The investigators want to retrospectively assess the satisfaction and quality of life of patients operated on for more than 2 years based on their epileptological results (frequency of seizures).

Conditions

• Epilepsy

Interventions

Type	Name	Description
OTHER	Epilepsy Surgery Satisfaction Questionnaire (ESSQ-19)	19 items assessing post-surgery satisfaction.
OTHER	Quality of Life in Epilepsy Inventory (QOLIE-31)	31 items to assess different dimensions of quality of life
OTHER	Generalized Anxiety Disorder 7 (GAD7)	7 items, rated from 0 to 3, to detect anxiety disorders.
OTHER	Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)	to screen for depressive disorders
OTHER	Evaluation of Changes in Daily Life after Epilepsy Surgery (EVOCQUE)	self-questionnaire developed by the Toulouse epileptology team in 2023 for patients who have undergone epilepsy surgery. It aims to collect the feelings of patients concerning the changes induced by surgery in their daily life according to a 7-point Likert scale.

Timeline

• Start date: 2023-11-30
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2023-09-13
• Last updated: 2023-12-18

Locations

1 site across 1 country: France