NCT06388174

Idiopathic Generalized Epilepsy Syndromes

Idiopathic Generalized Epilepsy Syndromes: Clinical Features and Long-term Outcomes

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: Shen Chun-Hong · Academic / Other
• Sex: All
• Age: 4 Years – 40 Years
• Healthy volunteers: —

Summary

The idiopathic generalized epilepsies (IGEs) have historically included the syndromes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCA). Recognition of the IGEs is important for clinical care, as it informs diagnosis, prevents unnecessary investigation, allows optimal selection of anti-seizure medications (ASMs), and provides prognostic guidance. According to the new ILAE definition in 2022, the study aims to describe the clinical features, electroencephalographic, imaging findings and long-term prognosis.

Detailed description

the Long-term prognosis include the rate of drug-resistent epilepsy, relapse after drug withdrawn, common comorbidities such as mood disorders, attention deficit hyperactivity disorder (ADHD) and learning disabilities.

Conditions

• Epilepsy
• Epilepsy, Idiopathic Generalized

Timeline

• Start date: 2023-01-01
• Primary completion: 2026-12-31
• Completion: 2033-12-31
• First posted: 2024-04-29
• Last updated: 2025-08-27

Locations

1 site across 1 country: China