NCT07226908

Human Thalamus in Propagation of Temporal Lobe Seizures and Memory Formation

• Status: Enrolling By Invitation
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of the study is to examine how two key subregions of the human thalamus (ANT and PLV) are connected with other brain structures (Aim 1), how seizures involve the two thalamic subregions differently and how the map of cortico-thalamic ictal propagation matches the intrinsic connectivity maps identified in the same individuals (Aim 2), and the effect of ANT and PLV stimulations on memory formation (Aim 3).

Conditions

• Epilepsy

Interventions

Type	Name	Description
OTHER	Cognitive experiment	Record brain activity during memory encoding
OTHER	Electrical stimulation of the brain	Measure accuracy and reaction time during cognitive tasks

Timeline

• Start date: 2024-09-01
• Primary completion: 2029-08-01
• Completion: 2029-08-01
• First posted: 2025-11-12
• Last updated: 2025-11-12

Locations

1 site across 1 country: United States