NCT07087821

NYU Epilepsy Self-Management Study

Economic Evaluation of Managing Epilepsy Well (MEW) Network Epilepsy Self-Management Programs

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 108 (estimated)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators will conduct two-arm randomized controlled trials (RCTs) comparing effects of UPLIFT vs. enhanced usual care and PACES vs. enhanced usual care, respectively, on quality of life, depressive symptoms and seizures over 12 months in NYU patients with epilepsy.

Detailed description

UPLIFT and PACES are two evidence-based epilepsy self-management programs whose adoption and impact are limited by the lack of sustainable funding models. The investigators will conduct an economic evaluation of these programs using data from completed and new trials in both healthcare and community settings. The investigators will conduct two parallel RCTs to compare effects of UPLIFT vs. enhanced usual care, and separately, PACES vs. enhanced usual care. Outcome data including patient-reported outcomes and costs will be aligned across the two trials and community implementation and collected at baseline and 3-, 6-, and 12-month follow-up visits for use in the economic evaluations.

Conditions

• Epilepsy

Interventions

Type	Name	Description
BEHAVIORAL	UPLIFT	UPLIFT is an 8-week epilepsy self-management programs delivered to small groups of people with epilepsy (PWE) by Webex. UPLIFT is focused on self-management of depressive symptoms. Each weekly session is 1 hour long and is comprised of a check-in period, teaching on the week's topic, group discussion, a skill-building exercise and a home practice assignment.
BEHAVIORAL	PACES	PACES is an 8-week epilepsy self-management programs delivered to small groups of people with epilepsy (PWE) by Webex. PACES focuses on general epilepsy self-management. Each weekly session is 1 hour long and is comprised of a check-in period, teaching on the week's topic, group discussion, a skill-building exercise and a home practice assignment.
BEHAVIORAL	Enhanced Usual Care	Participants receive referrals to local epilepsy support groups.

Timeline

• Start date: 2025-07-18
• Primary completion: 2027-09-29
• Completion: 2027-09-29
• First posted: 2025-07-28
• Last updated: 2025-07-28

Locations

2 sites across 1 country: United States