Clinical Trials Directory

Trials / Sponsors / Makerere University

Makerere University

Academic / Other · 140 registered clinical trials12 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingCall for Life Sepsis
Sepsis
N/A2026-03-15
Not Yet RecruitingEnhancing Comprehension of Consent in Patients With Psychotic Disorders
Psychosis
N/A2025-05-30
RecruitingUse of Unmanned Air Vehicles (Medical Drones) to Overcome Geographical Barriers to Delivery of Anti-Retroviral
HIV, Viral Load
N/A2025-03-18
RecruitingSelf-management Intervention for Reducing Epilepsy Burden Among Ugandans With Epilepsy.
Epilepsy
N/A2025-01-06
RecruitingCharacterization of Tuberculosis Associated Lung Fibrosis and Respiratory Impairment, and Prevention Using Dox
Tuberculosis, Pulmonary
Phase 22024-12-04
Enrolling By InvitationPeer Delivered HIV/Syphilis Self-Testing With Assisted Partner Notification Services
HIV, Syphilis
Phase 22024-08-25
Not Yet RecruitingDevelopment and Evaluation of an Information Management System and Communication System for Population-wide Po
Sickle Cell Disease
N/A2024-08-21
RecruitingMultimodal Analgesia Utilization and Acute Postoperative Pain After Major Surgery at Mulago National Referral
Pain
2024-08-08
Not Yet RecruitingImpact of a Community Based Engagement Program Focused on Adolescents With Epilepsy
Epilepsy
N/A2024-03-01
CompletedUsing SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in
Tuberculosis
N/A2023-08-14
UnknownEffectiveness of a Self-management App in Improving the Control of Asthma Among School Adolescents
Asthma
N/A2023-07-01
Not Yet RecruitingSolidarity/Tokomeza Ebola Trial
Sudan Ebola Virus Vaccines
Phase 1 / Phase 22023-07-01
CompletedThe Acute Respiratory Intervention StudiEs in Africa (ARISE-AFRICA) Study
Acute Respiratory Failure With Hypoxia, Acute Respiratory Distress Syndrome, Acute Lung Injury
N/A2023-03-13
UnknownClinical Trial of Natural Therapeutics for COVID-19 and Other Acute Respiratory Viral Infections
Acute Respiratory Infection
Phase 22023-03-03
UnknownPathogen Detection in HIV-infected Children With Non-malarial Febrile Illnesses Using Metagenomic Sequencing
HIV Infection
2023-01-01
UnknownEffectiveness of Intensive Adherence Counselling Among People Living With HIV/AIDS With Low-level Viraemia in
HIV/AIDS
N/A2022-09-12
UnknownIvermectin-artemisinin Combination Therapy for Eradication of Malaria
Malaria
Phase 42022-08-04
CompletedCaregiver Led Strategies to Malnutrition and Care-giving Among Children With Cerebral Palsy
Weight Gain
N/A2022-08-01
UnknownEffect of Digital Payment to Campaign Health Workers on Vaccination Coverage
Polio
N/A2022-07-01
UnknownEffectiveness of School Traffic Warden Programme on Road User Behaviour
Driver Yield to Pedestrians
N/A2022-06-06
UnknownIdeal Timing of Intrauterine Contraception Insertion After Medical Management of First Trimester Incomplete Ab
Incomplete Abortion, Intrauterine Contraception, Misoprostol
N/A2022-06-01
RecruitingAn Enhanced Package of Care to Reduce Reduce Mortality in Advanced HIV Disease
The Study Will Focus on Assessing the Survival Benefit on an Enhanced Package of Care for Patients With Advanced HIV Disease
Phase 32022-05-04
UnknownImproving Lifejacket Wear Among Boaters on Lake Albert, Uganda
Drowning
N/A2022-04-25
CompletedAirway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Coh
COPD, HIV Infections, Respiratory Disease
2022-04-01
UnknownSafety and Efficacy of COVIDEX™ Therapy in Management of Adult COVID-19 Patients in Uganda.
COVID-19
Phase 22022-03-01
UnknownPharmacogenetics-guided Isoniazid Dosing in TB-HIV
Tuberculosis
Phase 22021-12-07
CompletedSame-Day PrEP Initiation and Sexual Health for Transgender Women
HIV, PrEP, Transgender Women
N/A2021-11-02
UnknownOvercoming Geography With Technology: Medical Drones Project
Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections, COVID-19
2021-09-22
CompletedTransgender Men and HIV in Uganda: PrEP Uptake and Persistence
HIV, Sexually Transmitted Infections, PrEP
2021-09-16
UnknownThe Effect of Psycho-education on Clinical Outcomes Among Patients With a First Episode Psychosis in Central U
Psychosis
N/A2021-09-01
CompletedImplementation Science and Impact Evaluation of PfR Programme: A Hybrid cRCT Design
Parenting, Gender-based Violence, Child Maltreatment
N/A2021-08-06
UnknownStrategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutri
HIV-1-infection, Malnutrition, Child
Phase 2 / Phase 32021-06-14
UnknownAlveolar Cleft Reconstruction Powered by
Alveolar Cleft
N/A2021-06-01
UnknownVitamin D Supplementation in Children With Sickle Cell Disease
Children With Sickle Cell Disease at Mulago Hospital
N/A2021-05-17
CompletedDrug-drug Interactions Between Remdesivir and Commonly Used Antiretroviral Therapy
Ebola, HIV/AIDS
Phase 22021-05-05
UnknownEfficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids
Adipose Derived Stem Cells, Keloid
Phase 22021-05-01
CompletedAutologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.
Keloid, Autologus Adipose Derived Stem Cells, Feasibility
Phase 22021-03-01
UnknownUsing the ATC/DDD to Monitor Antibiotic Use at Lower Primary Care Facilities in Southwestern Uganda
ATC/DDD, Antibiotic Utilization
N/A2021-03-01
UnknownSafety & Efficacy of Low Dose Aspirin / Ivermectin Combination Therapy for Treatment of Covid-19 Patients
Covid19
Phase 2 / Phase 32021-02-19
UnknownHousehold-level Impact of IPT of Malaria in Schoolchildren
Malaria
Phase 32021-01-28
UnknownOptimizing Malaria Treatment for HIV-Malaria Co-infected Individuals
HIV Coinfection, Malaria
Phase 42021-01-18
CompletedMental Health in Communities Affected by COVID-19 in Uganda
Community Mental Health
N/A2020-11-01
UnknownPeer-Delivered HIV Self-Testing, STI Self-Sampling and PrEP for Transgender Women in Uganda
HIV, Sexually Transmitted Infections, PrEP
N/A2020-10-26
UnknownImpact of Mobile Health Interactive Software on Tuberculosis Outcomes; The Call for Life (CFLU-TB) Project
Tuberculosis
N/A2020-10-19
UnknownHydroxychloroquine for Treatment of Non-Severe COVID-19
Covid19
Phase 22020-09-18
CompletedCall for Life Youth ART Adherence Study
ART Adherence, HIV-1-infection, mHealth
N/A2020-08-12
UnknownGeriatric HIV Cohort in Sub Sahara Africa
HIV Infections, Non Communicable Diseases, Aging
2020-07-01
CompletedAssessment of Safety and Efficacy of CCP
Covid19
N/A2020-06-16
UnknownEffect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes
Fetal Distress, Birth Asphyxia
Phase 32020-03-16
UnknownWorkplace-based HIV Self-testing Among Men in Uganda (WISe-Men)
HIV Infections
N/A2020-02-01
UnknownAssessment of the Effectiveness of Continuous Labour Support by a Trained Companion of Choice on Events of Lab
Labor Long
N/A2019-12-30
UnknownOptimizing HIV Virologic Outcomes for Pregnant Women in Uganda
HIV
N/A2019-09-19
UnknownNucleosides And Darunavir/Dolutegravir In Africa
Human Immunodeficiency Virus
Phase 32019-07-30
CompletedThe COPD Attack Study
Pulmonary Disease, Chronic Obstructive, Exacerbation COPD
2019-07-07
RecruitingSingle Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia
Cryptococcal Meningitis
Phase 2 / Phase 32019-06-20
CompletedSafety and Efficacy of High Dose Rifampicin in Tuberculosis (TB)-HIV Co-infected Patients on Efavirenz- or Dol
Tuberculosis
Phase 22019-04-30
UnknownDetermining Bacterial Communities in the Lungs of HIV-infected Individuals With COPD in Uganda.
COPD, HIV/AIDS
2019-01-11
UnknownDarunavir and Rilpivirine Interactions With Etonogestrel Contraceptive Implant
HIV, Contraception
Phase 22018-09-25
UnknownPreventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Random
Preventing Stroke in Sickle Cell Anaemia
Phase 2 / Phase 32018-08-22
UnknownMechanical Ventilation Practices in Uganda's Intensive Care Units
Mechanically Ventilated Patients
2018-08-14
CompletedMisoprostol Treatment of Mid Trimester Incomplete Abortion by Midwives and Doctors in Uganda.
Incomplete Abortion
N/A2018-08-14
UnknownDarunavir and Rilpivirine Interactions With Levonorgestrel Implant
HIV-1-infection, Contraception
Phase 22018-08-07
CompletedIncidence and Factors Associated With PONV in Regional Anaesthesia
PONV, Regional Anaesthesia
2018-08-01
UnknownWHO Checklist- Based Infection Prevention Guidelines in Mulago Hospital
Surgical Site Infection
2018-07-16
UnknownVideo-Debriefing for Improved Competence Among Skilled Birth Attendants in Lira District-Northern Uganda
Neonatal Encephalopathy, Helping Babies Breathe (HBB) Training
N/A2018-06-04
UnknownDetecting and Treating Subclinical Anthracycline Therapy Related Cardiac Dysfunction in Low Income Country.
Chemotherapy Related Cardiac Dysfunction
Phase 32018-06-01
UnknownSpringfusor for Administration of Magnesium Sulphate in Preeclampsia and Eclampsia
Preeclampsia and Eclampsia
N/A2018-06-01
CompletedHIV Self-Testing to Empower Prevention Choices in Sex Workers
HIV/AIDS
N/A2018-05-21
UnknownThe Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
Uterine Fibroid
Phase 2 / Phase 32018-01-10
CompletedPreventing Mental Health Problems After Childhood Severe Malaria
Malaria
N/A2018-01-09
UnknownFunctional ICUS in Uganda and Their Survival Outcomes
Critical Illness
2018-01-08
CompletedSURVIVAL PLUSS: Increasing Capacity for Mama-baby Survival in Post-conflict Uganda and South Sudan
Neonatal Death, Preterm Birth, Low Birthweight
N/A2018-01-03
TerminatedComparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Pa
Critical Illness
Phase 2 / Phase 32017-10-22
UnknownEffect of Periodontal Care on Rhematoid Arthritis in Uganda
Rheumatoid Arthritis, Periodontal Diseases
N/A2017-09-01
CompletedIntra-abdominal Hypertension and Associated Factors Among Patients Admitted in Intensive Care Units in Uganda.
Intra-Abdominal Hypertension
2017-09-01
UnknownStatin Adjunct Therapy Among ART-treated Adults in Sub-Saharan Africa: Atorvastatin and Rosuvastatin Equivalen
HIV Infection
Phase 32017-06-01
UnknownThe Efficacy of Peer Support Model for Depression Care in Patients With Diabetes Mellitus
Diabetes Mellitus, Depression
N/A2017-04-01
UnknownDoxycycline for the Treatment of Nodding Syndrome
Seizures
Phase 22016-09-05
CompletedImproving Outcomes in HIV Patients Using Mobile Phone Based Interactive Software Support
Human Immunodeficiency Virus
N/A2016-08-23
CompletedIncidence and Associated Factors of Persistent Postoperative Incision Scar Pain Following C/s in Mulago Hospit
Chronic Pain
2016-07-06
CompletedPrevalence and Factors Associated With Postoperative Hypothermia in Mulago Hospital
Post Operative Hypothermia
2016-07-01
CompletedEarly Versus Late BCG Vaccination in HIV-1 Exposed Infants in Uganda in Uganda
Severe Illness, Septicaemia, Diarrhoea
Phase 32016-07-01
CompletedEfficacy of Umbilical Cord Cleansing With a Single Application of 4% Chlorhexidine for the Prevention of Newbo
Omphalitis, Septicaemia
Phase 42016-07-01
UnknownEffect of Preoperative Information About Pain on Postoperative Pain Experience and Patient Satisfaction
Post Operative Pain
N/A2016-06-01
CompletedCentral Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Sepsis, Septic Shock, Post-cardiac Surgery
2016-04-19
CompletedAfrican Severe Asthma Program: A Research Network for Characterisation of Severe Asthma in Africans (ASAP)
Severe Asthma
2016-04-01
CompletedWHO SSC : Compliance and Associated Surgical Outcomes in Uganda's Referral Hospitals
Surgical Safety Checklist Compliance, Perioperative Surgical Adverse Events
2016-04-01
CompletedSingle Dose Ceftriaxone and Metronidazole Versus Multiple Doses for Antibiotic Prophylaxis at Elective Cesarea
Post Operative Infections
Phase 42015-09-01
CompletedIncidence and Perioperative Factors Associated With Postoperative Delirium
Postoperative Delirium
2015-08-01
CompletedCAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT
Post Operative Pain
Phase 42015-07-01
CompletedLow-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers
Sickle Cell Crisis, Acute Pain
Phase 42015-06-01
CompletedEarly Tracheostomy Versus Standard of Care in Patients With Severe Head Injury
Severe Head Injury
N/A2015-06-01
UnknownSyphilis Treatment of Partners Trial
Syphilis Infection
N/A2014-11-01
CompletedAnalgesic Effects Of Dexamethasone; Its Use To Reduce Post Operative Pain Scores
Pain
Phase 22014-07-01
CompletedBalloon Palpation vs Loss of Resistance Syringe for Safe Endotracheal Tube Cuff Pressure; a Randomized Clinica
Tracheal Damage
N/A2014-04-01
CompletedIntegrated Hypertension and HIV Care Cascades in Uganda
Hypertension, HIV
2014-01-01
CompletedLabour Analgesia; Comparing a Combinations of Either Fentanyl or Bupivacaine With Intrathecal Morphine
Labor Pain
N/A2014-01-01
UnknownArtemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population Pharmacokinet
Malaria, Falciparum
Phase 42013-09-01
UnknownDemand Creation for Couples' HIV Counseling and Testing
HIV/AIDS
N/A2013-08-01
UnknownIntervention Trial to Measure the Effect of Individual Prenatal Information Combined With Mobile Phones
Pregnancy
N/A2013-06-01
UnknownSaving Brain in Uganda and Burkina Faso
Poor Performance Status, Neurologic Deficits, Mixed Behavior and Emotional Disorder
N/A2013-04-01
CompletedCatatonia in Nodding Syndrome and Lorazepam Treatment
Catatonia, Nodding Syndrome
Phase 12013-03-01
UnknownAlcohol Use and Risky Sexual Behaviors Among HIV Infected Subjects in Kampala Uganda
Alcohol Use, HIV
N/A2013-02-01
UnknownEvaluation of the Pharmacokinetics of Antituberculosis Drugs and Tuberculosis Treatment Outcomes
AIDS With Tuberculosis
Phase 42013-02-01
CompletedAtorvastatin for HAART Suboptimal Responders
Acquired Immune Deficiency Syndrome Virus
Phase 32013-01-01
CompletedSchistosoma Mansoni Morbidity in Children Aged 1-5 Years
Intestinal Schistosomiasis
Phase 22012-12-01
CompletedInhaled Corticosteroids in U-5 Children With Acute Respiratory Infection in Uganda: A Randomised Trial
Bacterial Pneumonia, Viral Pneumonia, Acute Asthma
Phase 32012-12-01
UnknownEvaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis
Schistosomiasis
N/A2012-10-01
TerminatedDextrose Infusion by Burettes Versus Dextrose Boluses in Prevention of Neonatal Hypoglycemia
Once a Preterm Developed Hypoglycemia, no More Blood Glucose Was Measured During the Study Period.
N/A2012-02-01
CompletedRinger's Lactate Versus Normal Saline in Caesarean Section
Normal Anion Gap Metabolic Acidosis
N/A2011-09-01
CompletedComputerized Cognitive Rehabilitation in Children After Severe Malaria
Malaria
N/A2011-04-01
UnknownThe Effect of Ketamine on Production of Inflammatory Markers in Post Operative Patients in Mulago Hospital
Post Operative Inflammatory Marker Levels
Phase 42011-04-01
CompletedSchool Based Malaria Control in Ugandan Schoolchildren
Malaria
Phase 32011-02-01
CompletedDrain or no Drain After Thyroid Surgery: a Randomized Clinical Trial at Mulago Hospital
Hospital Admission Duration, Postoperative Hematoma Formation, Wound Sepsis
N/A2010-12-01
CompletedEffect of Blood Storage Age on the Resolution of Lactic Acidosis in Children With Severe Malarial Anemia at Mu
Compare Blood Age for Transfusion
N/A2010-12-01
UnknownPharmacokinetics and Pharmacodynamics of Intravenous Artesunate for Severe Malaria Treatment
Severe Malaria
2010-05-01
CompletedAntiemetic Efficacy and Safety of Dexamethasone in Obstetric Surgical Patients
Postoperative Nausea and Vomiting
N/A2010-01-01
CompletedRadiotherapy + Metronidazole vs Radiotherapy Alone In Improving Treatment Outcomes in Advanced Cervical Cancer
Cervix Carcinoma
Phase 2 / Phase 32009-06-01
UnknownNon-Mesh Versus Mesh Method for Inguinal Hernia Repair
Hernia, Inguinal
N/A2009-05-01
UnknownCognitive and Psychosocial Benefits of MISC Training for Ugandan Children
HIV, HIV Infections
N/A2008-09-01
UnknownImpact of Family Psychoeducation on Psychosis
Postpartum Psychosis
N/A2008-08-01
CompletedNevirapine Drug Levels in HIV Positive Patients Also Receiving Rifampicin for Tuberculosis
HIV Infections, Tuberculosis
Phase 42008-05-01
CompletedRehabilitation Program for Cognitive Deficits in Ugandan Children After Cerebral Malaria
Malaria, Cerebral
N/A2008-02-01
CompletedAntiretroviral Drug Levels During and After Pregnancy
Pharmacokinetics
2008-02-01
CompletedDrug Interaction Study Between Lumefantrine and Lopinavir/Ritonavir
HIV Infections
Phase 42008-02-01
UnknownDrug Interaction Between Coartem® and Nevirapine, Efavirenz or Rifampicin in HIV Positive Ugandan Patients
HIV Infections, Tuberculosis
Phase 42008-02-01
UnknownEffectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan
Uncomplicated Malaria
Phase 42007-09-01
CompletedCotrimoxazole Versus Amoxicillin in the Treatment of Community Acquired Pneumonia in Children Aged 2-59 Months
Childhood Pneumonia
Phase 32007-07-01
CompletedComparison of Plasma Drug Levels of Triomune 40 With Those of the Originator Products
HIV Infections
Phase 42007-01-01
CompletedSulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemi
Sickle Cell Anemia, Malaria
Phase 32006-10-01
UnknownParasite-based Diagnosis for Malaria in Uganda: Feasibility and Cost-Effectiveness
Fever, Malaria
N/A2006-10-01
CompletedCeftriaxone Versus Chloramphenicol for Treatment of Severe Pneumonia in Children
Pneumonia
Phase 32006-09-01
CompletedThe Efficacy of Zinc as Adjunct Therapy in the Treatment of Severe Pneumonia in Children
Pneumonia
Phase 32006-09-01
CompletedTriomune Bioequivalence With Innovators
HIV/AIDS
Phase 42006-02-01
CompletedEffect of Multiple Micronutrient Supplementation on Growth, Morbidity, and Mortality of HIV Infected Children
HIV Infections
Phase 32005-06-01
UnknownReady to Use Therapeutic Food in the Rehabilitation of Severely Malnourished Children
Malnutrition
Phase 32004-10-01
UnknownMannitol as Adjunct Therapy for Childhood Cerebral Malaria
Cerebral Malaria
Phase 32004-10-01
CompletedEffectiveness of Inpatient Voluntary Counseling and Testing (VCT) in Uganda
HIV
N/A2004-02-01
UnknownEfficacy of Intrarectal Versus Intravenous Quinine for the Treatment of Childhood Cerebral Malaria
Cerebral Malaria
Phase 32003-09-01
CompletedEffect of Mass Deworming on Child Growth
Low Weight for Age in Preschool Children
N/A2000-08-01