Anesthesia, Local

292 registered clinical trials studyying Anesthesia, Local — 27 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Targeted Nerve Injection to the Knee (Nerve to Vastus Medialis): Comparing Two Adductor Canal Block Approaches NCT07444827	Duke University	Phase 4
Not Yet Recruiting	Bicarbonate Addition to Lidocaine-Epinephrine in Surgery Under WALANT NCT07342010	Centre Hospitalier Universitaire de Nīmes	Phase 4
Recruiting	Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty NCT07337772	First Affiliated Hospital of Fujian Medical University	N/A
Not Yet Recruiting	The Use of Electrical Stimulation for Determination of Epidural Catheter Placement NCT06055686	Stanford University	N/A
Withdrawn	Rib Microtia and the Erector Spinae Plane (ESP) Block NCT03729427	Stanford University	N/A
Not Yet Recruiting	Electrical Epidural Stimulation Test for Detecting Epidural Catheter Reactivation in Obstetric Population NCT04983511	Stanford University	N/A
Not Yet Recruiting	EIT Evaluation of Pulmonary Ventilation With Different Ropivacaine Concentrations in Intercostal Nerve Blockad NCT07079436	Fudan University	N/A
Completed	Ultrasonographic Optic Nerve Sheath Diameter in Postdural Puncture Headache Diagnosis NCT07100158	Ankara City Hospital Bilkent	—
Recruiting	Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements NCT06960317	University of California, San Diego	N/A
Not Yet Recruiting	Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement NCT06974019	University of California, San Diego	N/A
Not Yet Recruiting	Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement NCT06974032	University of California, San Diego	N/A
Not Yet Recruiting	Preoperative Block for Anterior Cervical Spine Surgery NCT06867510	Tanta University	Phase 3
Recruiting	Split Face Study of the Duration of Local Anesthetics - Fourth Arm NCT06694714	Weill Medical College of Cornell University	Phase 4
Completed	Soft Mist Nasal Administration Device for Topical Anaesthesia of the Nasal Cavity NCT06205680	Radboud University Medical Center	N/A
Not Yet Recruiting	Interest of Soft Point Anesthesia in Association With Locoregional Anesthesia in Arthroscopic Shoulder Surgery NCT06641167	GCS Ramsay Santé pour l'Enseignement et la Recherche	—
Completed	The Effect of Local Anesthetic Techniques on Hemodynamic Response and Postoperative Sore Throat in Double-Lume NCT06705595	V.K.V. American Hospital, Istanbul	N/A
Recruiting	A Pilot Study of Local Anesthesia for Inguinal Hernia Surgery in Older Adults NCT04706026	University of Wisconsin, Madison	N/A
Recruiting	Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery NCT06528288	University of Massachusetts, Worcester	N/A
Recruiting	Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular NCT06406010	Matias Vested	Phase 4
Not Yet Recruiting	Modified TIPS Block for Total Knee Arthroplasty NCT06539910	Alexandria University	Phase 4
Recruiting	SiFi vs FNB Local Anesthesia for Hip Fracture Surgeries NCT06296758	University of Alberta	N/A
Active Not Recruiting	Hypobaric L5-S1 Study NCT06526156	University Health Network, Toronto	—
Recruiting	Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure. NCT06520150	4th Military Clinical Hospital with Polyclinic, Poland	N/A
Completed	Suprainguinal Fascia Iliaca Block in Knee Arthroplasty NCT06386575	Konya City Hospital	N/A
Recruiting	Prediction Models for Cardiovascular and Neurocognitive Disease Risk in the General Population NCT05951764	Assistance Publique - Hôpitaux de Paris	—
Completed	Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block NCT06381622	Nordsjaellands Hospital	Phase 3
Completed	Efficacy of Inhaled Methoxyflurane (Penthrox) as Adjunct for Urologic Procedures Under Local Anesthetic: A Pil NCT07192198	University of Manitoba	Phase 2
Completed	Pain and Anxiety During Local Block NCT06352255	University of Seville	N/A
Recruiting	Effect of Fasting on Patient Outcomes After Wide-Awake, Local Anesthesia-only, No Tourniquet (WALANT) Procedur NCT05819801	University of California, Irvine	N/A
Unknown	Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery NCT06243263	University Tunis El Manar	Phase 4
Completed	Comparing Local Anesthetic Techniques for Clavicular Surgeries NCT06220591	Zagazig University	N/A
Recruiting	Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study) NCT06362915	Ain Shams University	Phase 1 / Phase 2
Completed	Type of Needle Bevel on Pain Perception in Children During Inferior Alveolar Nerve Block Anesthesia NCT06242743	Hams Hamed Abdelrahman	N/A
Unknown	Description of the Brachial Plexus Block at the Humeral Head in Children: a Sono-anatomical Study NCT06158243	Centre Hospitalier Universitaire Saint Pierre	—
Unknown	Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Su NCT06293586	Cairo University	N/A
Unknown	TIPS Block vs Dual Subsartorial Block NCT06096584	Alexandria University	Phase 4
Unknown	Utility of Exparel Based ESP Blocks in Elective Posterior Spine Fusion NCT06107660	Hartford Hospital	Phase 4
Unknown	Perioperative Pain Management for Total Shoulder Arthroplasty: A Pilot Non-Inferiority Trial NCT05908851	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's	N/A
Completed	Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerv NCT06038851	Centre hospitalier de l'Université de Montréal (CHUM)	N/A
Completed	The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers NCT05464862	Charlotte Runge	Phase 4
Enrolling By Invitation	Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients? NCT06057090	Medical University of South Carolina	N/A
Completed	Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial NCT06028126	Unity Health Toronto	N/A
Unknown	Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections NCT06011005	Mohammed Bin Rashid University of Medicine and Health Sciences	N/A
Unknown	Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Ped NCT05815563	Cairo University	—
Unknown	Vibratory Anesthesia in Trigger Finger Injections NCT05405452	University of Arizona	Phase 4
Unknown	Modified LPB and SPB vs Classical LPB and SPB NCT05901415	Peking Union Medical College Hospital	N/A
Completed	The Effect of Fascia Iliaca Compartment Block (FICB) on QoR-15 Score in Partial Hip Arthroplasty Surgery NCT05965544	Başakşehir Çam & Sakura City Hospital	N/A
Completed	Changes in Vessels After Peripheral Block NCT05968105	Başakşehir Çam & Sakura City Hospital	—
Enrolling By Invitation	Cervical Sympathetic Block in Patients With Cerebral Vasospasm NCT05230134	Stanford University	N/A
Unknown	Upper Trunk Block Feasibility by Anesthesia Residents NCT05932186	Alexandria University	Phase 4
Completed	The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine NCT05934253	Harrow Inc	Phase 4
Completed	Regional Analgesia for Anterior Cervical Disc and Fusion Surgery NCT05680142	Başakşehir Çam & Sakura City Hospital	N/A
Completed	Efficacy of Transversus Abdominis Plane Block NCT06274307	Justin Hruska	N/A
Recruiting	Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars NCT05964387	University of Michigan	N/A
Unknown	Impact of Tramadol Addiction On Dental Anesthesia Success NCT05908305	University of Algiers	Phase 4
Completed	Spinal Hypobaric Local Anesthetic Study NCT06166394	University Health Network, Toronto	—
Unknown	Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Cauda NCT05860010	Kasr El Aini Hospital	N/A
Completed	Efficacy and Safety of Administration of Different Doses of 4% Articaine. NCT06644950	University of Barcelona	N/A
Completed	Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor NCT05875519	Minia University	N/A
Completed	Lidocaine Administration Using STAR Particles NCT06034340	Emory University	N/A
Completed	Articaine Infiltration in Anesthetizing Mandibular Second Primary Molars NCT06201949	Hams Hamed Abdelrahman	N/A
Completed	Voice Quality Changes With IANB Anesthesia NCT05710484	Marmara University	—
Completed	Analgesic Territory Assessment of the Spinal Erector Block Using Pupillometry NCT05762159	Centre Hospitalier Universitaire de Saint Etienne	—
Completed	Intraligamental Local Anesthesia Versus Infiltration Technique for Extraction of Grade II Mobility Maxillary M NCT05875350	Minia University	N/A
Completed	Risk Factors of Inferior Alveolar Nerve Block Failure: a Dental Student-centered Study NCT05681546	Selcuk University	—
Unknown	ITP Block: Single or Multiple Injection? NCT05753397	Zealand University Hospital	Phase 4
Unknown	Non-invasive Measurement of Arterial Stiffness NCT05654402	Assistance Publique - Hôpitaux de Paris	—
Completed	Ultrasound Guided Sacral Erector Spina Plane Block as a Main Anesthetic Method NCT05674006	Samsun University	—
Completed	Dental Attire Effect on Children's Dental Anxiety NCT06122883	Damascus University	N/A
Unknown	Cold Vibratory Stimuli on Pain Perception Governing Infiltration Anesthesia in in Children NCT05857033	Alexandria University	N/A
Completed	Comparison of Ultrasound-guided Brachial Plexus Blocks and Selective Distal Blocks in Terms of Anesthesia NCT05656625	Samsun University	—
Completed	Caudal Epidural Vs. TAP Block for Postoperative Analgesia in Pediatric Infraumbilical Surgery: a RCT NCT06895382	Namik Kemal University	N/A
Completed	Comparison of Infraclavicular Block and Wide-Awake Local Anesthesia With No Tourniquet for Hand Surgery NCT06628882	Uludag University	N/A
Unknown	The Effect of Forearm Nerve Blocks on Pain-free Tourniquet Time Compared to Local Anesthetic for Awake Hand Su NCT04787835	University of Manitoba	N/A
Completed	The Effect of Bilateral Infraorbital+ Infratrochlear Nerve Block for Rhinoplasty Operations NCT05671237	Istanbul University	N/A
Active Not Recruiting	Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers NCT05603741	University of Calgary	Phase 4
Unknown	Diode Laser on the Reversal of Inferior Alveolar Nerve Block Anesthesia in Children NCT05648981	Hams Hamed Abdelrahman	N/A
Completed	Double-dorsal Versus Single-volar Digital Block NCT06274073	Ankara City Hospital Bilkent	N/A
Unknown	The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder NCT05415865	Herlev and Gentofte Hospital	Phase 3
Completed	A Safety Study of of AG-920 Sterile Topical Ophthalmic Solution NCT05501860	American Genomics, LLC	Phase 3
Completed	Soft Mist Spray Device for Airway Anaesthesia During Awake Videolaryngoscopy NCT05478122	Radboud University Medical Center	N/A
Unknown	Comparison of US-guided Single-dose Thoracic Paravertebral, Erector Spinae Plane and Serratus Anterior Plane B NCT05431062	Istanbul University	N/A
Completed	Self-Reported Pain in Children Submitted to Single Infiltration of Articaine During Primary Molar Extraction NCT05443009	Universidade Federal de Santa Catarina	Phase 4
Completed	Pain and Anxiety Reduction Using a Vibrating Eye Massage Device With Relaxing Nature Sounds NCT05592587	Damascus University	N/A
Completed	Thoracic Intervertebral Foramen Block NCT05603442	San Salvatore Hospital of L'Aquila	Phase 3
Completed	Cerebral Oxymeter and End Tidal Carbondioxide Values Under Surgical Drapes With and Without Past COVID-19 Infe NCT05571683	Duzce University	—
Unknown	Compare the Efficacy of Various Pain Alleviating Methods in Reducing Pain in Children During Intraoral Local A NCT05564442	Minia University	N/A
Unknown	Bupivacaine Versus Lidocaine Infiltration for Postoperative Pain in Thyroid Surgery NCT04427904	St. Joseph's Healthcare Hamilton	Phase 2
Withdrawn	Suprainguinal Fascia Iliaca Compartment Block in Direct Anterior Approach to Total Hip Arthroplasty NCT05237479	Montefiore Medical Center	N/A
Completed	Postoperative Experience of 2 WALANT-type Modes of Anesthesia Used in Ambulatory Surgery of the Upper Limb. NCT05343299	Centre Hospitalier Universitaire de Nīmes	Phase 1
Recruiting	ESP Block Versus Wound Infiltration for Laminectomy NCT05271331	University of Padova	N/A
Completed	Bacteriostatic Saline as a Local Anesthetic in Minor Eyelid Procedures NCT05294640	University of California, San Francisco	Phase 4
Unknown	Evaluation of Efficacy of Intraligamentary Anesthesia for Mandibular Molar Extractions NCT05122819	Hamdard University	N/A
Completed	A Study of Safety and the Local Anesthetic Effect of AG-920 Ophthalmic Solution in a Pediatric Population NCT05325853	American Genomics, LLC	Phase 3
Completed	Assessment of Pain, Anxiety and Efficiency of NumBee Compared to Traditional Local Anesthetic Syringe NCT05899296	Duaa Kamal Naji	N/A
Unknown	Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techni NCT05233683	King Saud University	Phase 3
Completed	Analgesia in Minimally Invasive Direct Coronary Artery Bypass Grafting: Programmed Intermittent Bolus Infusion NCT05320718	Peking University Third Hospital	N/A
Completed	Efficacy of VR Distraction During Local Anesthesia in Children NCT05129943	Tishreen University	N/A
Completed	Effect of Virtual Reality (VR) Therapy on Patients Undergoing Hand Surgery Under Ultrasound-guided Regional An NCT05183412	Jessa Hospital	N/A
Completed	Ropivacaine Plus Magnesium Sulphate Infiltration NCT05294393	Aristotle University Of Thessaloniki	Phase 4
Completed	Anethesia Efficacy on Teeth With MIH (Molar Incisor Hypomineralisation) NCT05344014	Kocaeli University	N/A
Unknown	The Anesthetic Efficacy of Lidocaine and Articaine as Buccal Injection for Maxillary Premolar Teeth Extraction NCT05951907	University of Baghdad	N/A
Withdrawn	Comparison of Erector Spinae Plane Block With PECS II Block in Patients Undergoing Breast Cancer Surgery NCT03811262	University of Padova	N/A
Completed	Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caes NCT05348083	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	—
Unknown	Effectiveness of iPACK on Postoperative Pain From Hamstring Autograft Following ACL Repair NCT05080348	Brenton Alexander	N/A
Completed	The CIA Score: a Learner's Tool NCT05153265	Stanford University	—
Unknown	Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline NCT05109000	Jeffrey Alan Klein, MD	Phase 4
Withdrawn	Effective Use of Pecs and Transversus Thoracics Plane Blocks for Subcutaneous Cardiac Pacemaker Insertion: A C NCT03899701	Montefiore Medical Center	N/A
Completed	Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and NCT06693427	DIMITRIOS KATSAROS	—
Completed	A Comparison Between a PC and a CC Approach for the Placement of Infraclavicular Perineural Catheters in Hand NCT04960046	Centre hospitalier de l'Université de Montréal (CHUM)	N/A
Unknown	Effect of External Cold and Vibration (Buzzy Device) Versus the Conventional Technique on Pain Perception Duri NCT05067218	Cairo University	N/A
Completed	Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery NCT04916418	Turku University Hospital	Phase 4
Unknown	Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades NCT05038007	Jannie Bisgaard Stæhr	Phase 2
Completed	Unilateral Laparoscopic TAP Block vs. Local Infiltration in Post-Cholecystectomy Analgesia NCT07176299	University of Warmia and Mazury in Olsztyn	N/A
Withdrawn	Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Chi NCT03779659	Boston University	N/A
Completed	Oral Dexamethasone as an Adjunct to a Brachial Plexus Block in Patients Undergoing Orthopaedic Surgery of the NCT04853446	Zealand University Hospital	Phase 4
Completed	Regional Anesthesia in Pediatric Orthopaedic Patients NCT04669145	Ochsner Health System	Phase 2 / Phase 3
Unknown	To Evaluate Reduction of Pain in Wounds Treatment Previously Applying Lidocaine Topical Solution vs Placebo. NCT03676556	Hospital Universitari de Bellvitge	Phase 3
Terminated	iPACK Block With Dexamethasone For Total Knee Replacement NCT04917055	University of California, San Diego	Phase 4
Completed	Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in NCT04818749	Zealand University Hospital	Phase 4
Unknown	Efficacy of iv Fentanyl Citrate Administered Oral as a Pediatric Premedication NCT04991298	University of Alexandria	N/A
Recruiting	Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection NCT04849455	University of California, San Diego	Phase 4
Terminated	Continuous Erector Spinae Plane Blocks for Rib Fractures NCT04558281	University of California, San Diego	Phase 4
Completed	Accuracy of Manual Palpation vs Ultrasound for Spinal Anesthesia NCT04757805	Nationwide Children's Hospital	N/A
Unknown	Effect of the Transmuscular Quadratus Lumborum Block on Duration of Stay in Recovery NCT04951752	Zealand University Hospital	—
Completed	Transcutaneous Electrical Nerve Inhibition Using Medium-frequency Alternating Current NCT04827173	Jessa Hospital	N/A
Completed	Paravertebral Block to Reduce the Incidence of New Onset Atrial Fibrillation After Cardiac Surgery NCT04472299	University of Minnesota	Phase 4
Completed	Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effe NCT04817982	Zealand University Hospital	Phase 2
Completed	Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics NCT04782778	Istanbul University	N/A
Completed	Comparison of Ultrasound-guided Bilateral ESP Block and Wound Infiltration for Spinal Surgical Analgesia NCT04642625	Trakya University	—
Unknown	Subconjunctival Bupivacaine in Strabismus Surgery NCT04782960	Fayoum University	N/A
Completed	A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution NCT04829344	American Genomics, LLC	Phase 3
Unknown	Can a Subcostal Nerve Block Add Benefit to a Lateral Femoral Cutaneous Nerve Block for Open Hip Surgery NCT04779580	The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust	N/A
Completed	Comparison of Pre-procedure Lignocaine Spray Versus Spray-as-you-go for Topical Airway Anesthesia in Flexible NCT07084623	Sheikh Zayed Federal Postgraduate Medical Institute	N/A
Unknown	Evaluation of Buffered Local Anesthesia in Dental Extraction. NCT04773236	University of Baghdad	Phase 4
Completed	ESP in Breast Surgery Due to Cancer NCT04726878	Medical University of Lublin	Phase 4
Completed	Ultrasound-guided Regional Anesthesia vs Local Infiltration Anesthesia With Dexmedetomidine and Ropivacaine NCT04697537	Medical University of Graz	Phase 3
Unknown	Uterovaginal Plexus Block With Articaine for Intrauterine Device Placement Patients Who Are Indicated for the NCT05252117	Universidade do Vale do Sapucai	Phase 4
Completed	Efficacy of Ultrasound-guided Axillary Nerve Block Versus Ultrasound-guided Peripheral Forearm Block in Patien NCT04678765	Jessa Hospital	N/A
Completed	Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia NCT04750512	Ghielmini Enea	N/A
Completed	Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face NCT04523961	Mayo Clinic	Phase 2 / Phase 3
Completed	Erector Spinae Plane Block Versus Paravertebral Block for Analgesia After Cardiac Surgery (PEPS) NCT04546113	Institut Mutualiste Montsouris	N/A
Completed	ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DIS NCT05483647	Lviv National Medical University	N/A
Unknown	General Anesthesia, Versus Axillary Block for Ambulatory Hand Surgery: Randomized Prospective Study NCT04727515	Ain Shams University	N/A
Unknown	EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial NCT04879004	Democritus University of Thrace	N/A
Completed	SEQ Block for Perioperative Analgesia in Acetabular Surgery NCT04688814	Alexandria University	Phase 3
Completed	Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric P NCT04298099	Baylor College of Medicine	Phase 4
Unknown	Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Sp NCT04697498	Lviv National Medical University	N/A
Recruiting	Obstetric Placement Study Using EST NCT04109365	Stanford University	N/A
Completed	WALANT Procedure in Carpal Tunnel Release NCT04924348	Elsan	N/A
Unknown	Ultrasound-guided Lumbar Erector Spinae Plane Block in Patients Undergoing Lower Limb Vascular Surgery NCT04644562	Beni-Suef University	N/A
Unknown	Buffered vs Plain Lidocaine for Local Nasal Anesthesia NCT04583137	Kfir Siag	EARLY_Phase 1
Completed	IPICK Blocking for TKA With Moderate Flexion Contracture NCT04603950	The First Hospital of Jilin University	N/A
Completed	Regional Anesthesia for Totally Awake Upper Limb Surgery in PEDiatric Population NCT04846855	Ramsay Générale de Santé	Phase 4
Withdrawn	Scalp Block: Hemodynamic Stability and Patient Comfort In Craniotomy Patients NCT03177252	Washington University School of Medicine	Phase 1
Completed	General Anesthesia and Paravertebral Blocks vs. General Anesthesia Only: Influence Inflammation Factors and Cl NCT04540055	Udayana University	—
Unknown	Efficiency of Single Buccal Infiltration Versus Buccal and Intrapapillary Infiltration NCT04458142	Cairo University	N/A
Withdrawn	Ice as an Adjunct for Local Anesthesia During Anorectal Surgeries NCT04000191	Boston Medical Center	N/A
Completed	A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution NCT04513652	American Genomics, LLC	Phase 3
Completed	Analgesic Efficacy of Ultrasound Guided Bilateral Erector Spinae Plane Block in Pediatric. NCT04452656	Cairo University	N/A
Completed	Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses NCT04458467	University of California, San Diego	N/A
Completed	LPB Combined with QLB Using Single-needle Technique (LPQLB-SNT) for Hip Arthroplasty NCT04266236	Shanghai 6th People's Hospital	N/A
Completed	Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy NCT04019834	University of Alabama at Birmingham	EARLY_Phase 1
Completed	Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block NCT04562103	Fondazione Policlinico Universitario Agostino Gemelli IRCCS	N/A
Completed	Dental Anaesthesia Affects Pain Level NCT05002673	Karadeniz Technical University	N/A
Completed	Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy NCT04440475	ProMedica Health System	N/A
Completed	Efficacy of Dexmedetomidine Versus Morphine as an Adjunct to Bupivacaine in Caudal Anesthesia. NCT04445636	Cairo University	N/A
Completed	Serratus Anterior Plane Block in Pediatric Patients NCT04444635	Cairo University	N/A
Unknown	Efficacy of Intraseptal Anesthesia of 4% Articaine With Epinephrine Achieved by Computer-controlled Delivery S NCT04392804	University of Belgrade	—
Unknown	Suprascapular Nerve Block Efficacy for Shoulder Surgery NCT04364542	Ivan Simionato	N/A
Completed	Open Radical Prostatectomy and Erector Spinae Plane Block NCT04337060	BURHAN DOST	N/A
Completed	Lateral Sagittal vs Costoclavicular Approach for Ultrasound-Guided Infraclavicular Block NCT04356521	Ondokuz Mayıs University	N/A
Unknown	Block of the Sphenopalatine Nerve Ganglion for Postoperative Analgesia NCT04339231	Universidade Federal Fluminense	N/A
Terminated	Use of Long-acting Bupivacaine In Lower Extremity Amputation NCT04360421	Loma Linda University	Phase 4
Completed	The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement NCT05382624	Ataturk University	—
Unknown	High Ankle Block in Ankle Fractures NCT04292691	Ludwig-Maximilians - University of Munich	N/A
Completed	Ultrasound-guided Paravertebral Block Versus Mid-point Transverse Process Pleura Block in Mastectomy Surgery NCT05332028	Ataturk University	Phase 4
Completed	Comparison of The Effectiveness of Intraligamentary and Mandibular Anesthesia on Mandibular Molar Teeth NCT05115773	Izmir Katip Celebi University	N/A
Completed	Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean Delivery NCT04748224	Cairo University	N/A
Completed	Massage and Electroacupuncture in Chronic Lumbar Pain NCT04108546	University of Thessaly	N/A
Completed	Serratus Plain Block Versus Paravertebral Block Versus Serratus Plain Block and Paravertebral Block for Postop NCT04222010	Centre Hospitalier Universitaire, Amiens	Phase 3
Unknown	Regional Anesthesia for Cardiothoracic Enhanced Recovery NCT03781440	Stanford University	N/A
Completed	Comparison of Lateral and Medial Approaches to Costoclavicular Brachial Plexus Block in Pediatrics NCT04786756	Istanbul University	N/A
Withdrawn	Regional Anesthesia Block in Fibula Free Flap Reconstruction NCT03906838	University of Florida	EARLY_Phase 1
Unknown	Evaluation of Duration of Anesthesia and Patient Satisfaction After Retrobulbar Block Applied in Cataract Surg NCT04178200	Develi Devlet Hastanesi	—
Completed	Liposomal Bupivacaine Versus Bupivacaine for for Postoperative Pain Control in Shoulder Surgery NCT04180943	Bassett Healthcare	Phase 4
Completed	Epidural Catheter Location by Epidural Pressure Waveform NCT04205773	European e-Learning School in Obstetric Anesthesia	—
Completed	Surgical Stabilization of Rib Fractures While Awake or Under Appropriate Sedation by Paravertebral Block NCT04536311	Shanghai Jiao Tong University Affiliated Sixth People's Hospital	N/A
Unknown	Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in C NCT03917121	Cairo University	N/A
Unknown	Lumbar Erector Spinae Plane Block for Back Surgery NCT03825198	Dr M. B. Breebaart	Phase 3
Completed	Intrauterine Anesthesia in Operative, Awake, Office Hysteroscopy. A Randomized Double-blind Placebo-controlled NCT05610371	Assuta Ashdod Hospital	N/A
Unknown	Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration NCT03927326	University of Washington	N/A
Active Not Recruiting	Intralipid® 20% for Reversal of Local Anesthetics NCT03968822	Hospital for Special Surgery, New York	Phase 4
Active Not Recruiting	Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers NCT04036305	Vanderbilt University Medical Center	—
Suspended	Needle-free Dental Anesthesia NCT04493528	McGill University Health Centre/Research Institute of the McGill University Health Centre	N/A
Completed	Peak Plasma Levels of Bupivacaine After an Erector Spinae Block (ESP) NCT03841409	Centre hospitalier de l'Université de Montréal (CHUM)	—
Completed	Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery NCT03807505	Stanford University	N/A
Completed	Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study NCT03611374	Stanford University	N/A
Unknown	Transconjunctival vs Transcutaneous Anaesthesia in Oculoplastics NCT04102878	University Hospital Southampton NHS Foundation Trust	N/A
Completed	Wide-awake Local Anesthesia and no Tourniquet (WALANT) in Plastic Surgery NCT04992351	University Hospital, Ioannina	—
Completed	Should Maxillary Buccal Infiltration Anesthesia be Given in a Closed Mouth Technique? NCT03921190	University of Jordan	N/A
Completed	Long Term Safety of Cooling Anesthesia for Intravitreal Injection NCT03956797	Recens Medical, Inc.	N/A
Unknown	5 Versus 10 Sprays of Lignocaine for Pharyngeal Anaesthesia During Bronchoscopy NCT03869528	All India Institute of Medical Sciences	N/A
Completed	Comparion of Erector Spinae Plane Block and Quadratus Lumborum Block in Laparoskopic Cholecystectomy NCT03869801	Maltepe University	N/A
Unknown	Study of Two-step Anesthesia in Intravitreal Injection NCT03871062	Aier School of Ophthalmology, Central South University	N/A
Completed	ED50 and ED95 of Isobaric Bupivacaine for Post-Partum Bilateral Tubal Ligation NCT03779568	University of Texas Southwestern Medical Center	N/A
Unknown	Ropivacaine 0,2% Plus Dexamethasone Versus Ropivacaine 0,2% Plus Placebo in Modified Pectoral Block NCT03700177	Medical University Innsbruck	Phase 4
Unknown	Preoperative Paravertebral Block in Cancer Surgery of the Lung NCT04209868	Guy's and St Thomas' NHS Foundation Trust	Phase 2 / Phase 3
Terminated	MORphine Use in the Fascia Iliaca Compartment Block With UltraSound NCT03846102	Zuyderland Medisch Centrum	Phase 4
Unknown	Single-centre Study to Investigate Safety and Efficacy of Tri-Solfen in Wound Debridement NCT03865147	Medical Ethics UK Ltd	Phase 2
Completed	Exparel Use in Bilateral TAP Blocks for Postoperative Pain Control NCT03878888	St. Luke's Hospital, Pennsylvania	Phase 4
Completed	Comparing Two Anesthetic Techniques for Implant Placement NCT04395690	Aula Dental Avanzada	N/A
Completed	Comparing Analgesic Effects of Caudal and Erector Spinae Plane Blocks in Pediatrics Undergoing Upper Abdominal NCT04204343	Istanbul University	N/A
Completed	Comparing Analgesic Effects of Three Ultrasound Guided Regional Anesthetic Techniques in Pediatrics NCT03780790	Istanbul University	N/A
Completed	Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental P NCT03790540	Nourhan M.Aly	Phase 2
Completed	Cooling Anesthesia for Intravitreal Injection NCT03732287	Recens Medical, Inc.	Phase 1 / Phase 2
Completed	Changes of Regional Tissue Oxygenation Saturation After Successful Femoral Nerve Block NCT03753594	Huazhong University of Science and Technology	—
Completed	Quadratus Lumborum Block (Transmuscular Approach) VS. TransversusAbdominus Plane Block(Unilateral Posterior Ap NCT03744923	Cairo University	N/A
Unknown	A Trial Comparing Pain During Local Tumesent Injection In Fingers Using Different Syringe-Needle Combinations NCT03736915	Fakultas Kedokteran Universitas Indonesia	N/A
Completed	Bier's Block Versus Mini-bier's Block in Patients Undergoing Hand Surgery NCT03761329	Jessa Hospital	N/A
Completed	Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade NCT03677778	Stanford University	N/A
Completed	The Efficacy of Suprainguinal Fascia Iliaca Compartment Block for Analgesia After Elective Total Hip Replaceme NCT04690647	Saint Lucas Hospital, Poland	N/A
Unknown	Wound Infiltration as Part of an Opioid Free Pain Management Pathway Following Cesarean Delivery NCT03545516	Richmond University Medical Center	Phase 2
Terminated	Perineal Local Infiltration Study NCT03672500	Sunnybrook Health Sciences Centre	N/A
Completed	Continuous TQL Block for Elective Cesarean Section NCT03663478	Zealand University Hospital	Phase 4
Completed	The Effect of Anesthesia on Perioperative Muscle Weakness and Neuro-endocrine Stress Response NCT03600454	Ziekenhuis Oost-Limburg	N/A
Completed	Local Anesthesia With Minimal Sedation and Brachial Plexus Block in Hand Surgery NCT03632304	McGill University Health Centre/Research Institute of the McGill University Health Centre	N/A
Completed	A Study to Evaluate the Efficacy and Safety of Zingo in Chinese Children NCT03653260	Lee's Pharmaceutical Limited	Phase 3
Unknown	Study of Two-step Anesthesia in Posterior Vitrectomy NCT03577574	Aier School of Ophthalmology, Central South University	N/A
Unknown	A Comparison of Local Infiltration Analgesia and Pecs Block for Analgesia in Mastectomy With Axillary Dissecti NCT03602794	Louis Ng Xiang Long	N/A
Completed	Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Y NCT03562481	University of North Carolina, Chapel Hill	Phase 4
Terminated	Erector Spinae Plane (ESP) Versus Paravertebral Nerve (PVB) Blockade for Acute Unilateral Rib Fracture Pain NCT03540095	University of Pittsburgh	N/A
Completed	Analgesic Efficacy of Lidocaine Plus Bupivacaine Versus Bupivacaine Alone Caudally NCT03911648	Ayancık State Hospital	—
Completed	Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Versus Tecnica Single-shot Nei Pazienti Sottoposti ad NCT05868642	Istituto Ortopedico Rizzoli	N/A
Completed	Variable Perception of Cutaneous Stimulation NCT03467685	University of Pittsburgh	N/A
Completed	Erector Spinae Plane Block Versus Paravertebral Block NCT03471442	University of Alberta	N/A
Completed	Efficacy of Local Direct Median Nerve Block NCT04453462	Thammasat University	N/A
Terminated	Treatment Prior to Injection and Biopsy of the Vulva NCT03444727	University of Missouri-Columbia	N/A
Completed	Pre-Operative Single Shot Rectus Sheath Block NCT03458598	University of Alberta	N/A
Unknown	Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anestheti NCT03149783	University of Colorado, Denver	Phase 2
Completed	Dual Guidance in Regional Anesthesia NCT03383770	Charite University, Berlin, Germany	N/A
Terminated	A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin NCT03399435	Grünenthal GmbH	Phase 1
Completed	Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications NCT03423329	Ain Shams University	N/A
Completed	Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Rele NCT03411551	Jessa Hospital	N/A
Completed	Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants NCT04498923	Lviv National Medical University	—
Completed	Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures NCT03305666	Denver Health and Hospital Authority	Phase 4
Completed	Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks NCT03245359	AdventHealth	N/A
Suspended	Protective Nerve Stimulation in Regional Anesthesia NCT03291691	Charite University, Berlin, Germany	—
Unknown	Platelet-rich Fibrin on Nerve Regeneration After Bilateral Sagittal Split Osteotomy NCT03159338	Shiraz University of Medical Sciences	N/A
Completed	A Split Mouth Trial to Compare Microneedles vs. Standard Needles in Dental Anaesthetic Delivery NCT02966067	University of Dublin, Trinity College	N/A
Terminated	PACMAN Ultrasound Recording Data Collection NCT03368976	Avanos Medical	—
Unknown	Evaluation of Second Esmarch Application on Intravenous Regional Anesthesia Effectiveness NCT03702387	University of Arizona	N/A
Completed	Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion NCT03111342	University of Sao Paulo	Phase 4
Completed	Cutaneous Anesthesia of the Lateral Femoral Cutaneous Nerve NCT03138668	Zealand University Hospital	Phase 2
Unknown	Comparison Between Efficiency of Inferior Alveolar Nerve Block and Buccal Infiltration Techniques Using Artica NCT03130855	Cairo University	N/A
Completed	Clinical Outcomes Mandible: Buffered 1% vs. Non-Buffered 1% Lidocaine NCT03127943	University of North Carolina, Chapel Hill	Phase 4
Completed	The Effect of Needle-free Injection System on Dental Injection Pain in Children NCT06541925	Marmara University	N/A
Completed	Anesthetic Efficacy of PECS II Block and Parasternal Block NCT03016117	San Salvatore Hospital of L'Aquila	N/A
Completed	Reversing the Effects of 0.5% Bupivacaine NCT02995291	Dalhousie University	Phase 4
Completed	Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia NCT03628430	Faculty of Medicine, Sousse	N/A
Unknown	Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis NCT02986997	Medical University of Warsaw	—
Completed	Sensory Distribution of Lateral Femoral Cutaneous Nerve Block NCT02957903	Zealand University Hospital	Phase 4
Completed	Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success NCT03174860	Cairo University	Phase 2 / Phase 3
Withdrawn	Improving Pain Relief Following Laparoscopic Ventral Hernia Repair NCT02785276	University of Auckland, New Zealand	N/A
Completed	Liposomal Bupivacaine in Total Knee Arthroplasty NCT03541265	Bronx-Lebanon Hospital Center Health Care System	N/A
Completed	Evaluation of a Novel Medical Device to Facilitate Gel Instillation During Change of Long-term Urinary Cathete NCT03289117	Region Skane	N/A
Completed	Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block NCT02718976	University of Aarhus	Phase 2
Unknown	Optimal Volume of Bupivacaine in Adductor Canal Nerve Block NCT02557386	Pontificia Universidad Catolica de Chile	Phase 4
Completed	Phentolamine Mesylate as a Reversal of Local Anesthesics NCT03740386	León Formación	N/A
Completed	Serum Bupivacaine Concentration Levels After Injection of Liposomal Bupivacaine Into the Knee NCT02626559	University of Utah	—
Completed	Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block NCT02593370	Thomas F. Bendtsen	Phase 1
Completed	PDL Anesthesia Versus Local Infiltration NCT03173898	University of Jordan	N/A
Completed	Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb NCT02713685	Government Medical College, Haldwani	N/A
Completed	Evaluation of the Dental Vibe Injection Comfort System NCT04971941	Harvard Medical School (HMS and HSDM)	N/A
Completed	Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus NCT02255591	University of Aarhus	Phase 4
Unknown	Local Anesthesia in Radial Catheterization NCT03072394	Hippocration General Hospital	Phase 4
Unknown	Efficacy of the Ultrasound-guided Transversus Abdominis Plane Block in Open Aortic Abdominal Aneurysm Repair S NCT02292667	Centre Hospitalier Universitaire de Besancon	Phase 3
Unknown	Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars NCT02353676	Cosmozone Dental Clinic	N/A
Completed	RAOLA Observational: Local Anesthesia During Cardiac Catheterization NCT03091049	Hippocration General Hospital	—
Completed	The Cardiovascular Changes Associated With Septal Local Anaesthesia NCT03137615	Sheffield Teaching Hospitals NHS Foundation Trust	—
Completed	Local Anesthesia for Pediatric Cochlear Implant NCT03721081	Wahba bakhet	Phase 4
Unknown	A Trial of Local Anaesthesia Versus Local Anaesthesia and Conscious Sedation for Hernioplasty NCT02444260	The University of The West Indies	Phase 3
Completed	Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block NCT03117140	Melinda Seering	Phase 4
Completed	A Study Investigating Properties of the Transversus Abdominis Plane Block NCT01679392	Hillerod Hospital, Denmark	N/A
Completed	Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients NCT01474382	Novocol Pharmaceutical of Canada, Inc.	Phase 4
Completed	Visibility - Classification of Sono-visibility of Anatomical Structures in Peripheral Nerve Blocks NCT03231696	Charite University, Berlin, Germany	—
Completed	Changes in Tissue Oxygenation Following Regional Anesthesia NCT01418690	Nationwide Children's Hospital	—
Completed	Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method NCT02988219	Medical University of Warsaw	Phase 4
Completed	Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard Analgesia NCT01751256	Poissy-Saint Germain Hospital	Phase 4
Completed	Peribulbar Block: Lidocaine-bupivacaine vs Lidocaine-bupivacaine-fentanyl NCT03713762	Centro Medico Docente la Trinidad	Phase 3
Terminated	The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine NCT00801138	The Cleveland Clinic	N/A
Completed	Behavior of Children Related to Numbness After Dental Local Anesthesia NCT00363207	Hadassah Medical Organization	—