NCT05038007

Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades

Pain After Thoracoscopic Lung Surgery - the Effect of Intercostal Nerve Blockades With Standard Bupivacaine and Liposomal Bupivacaine - a Randomised Controlled Feasibility Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Jannie Bisgaard Stæhr · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To investigate the effect of liposomal bupivacaine compared with bupivacaine hydrochloride for intercostal blockades for patients undergoing Video-assisted thoracoscopic surgery.

Detailed description

Video-assisted thoracoscopic surgery (VATS) is a minimally invasive routine procedure. It's less invasive than thoracotomy but postoperative pain is still a problem. At Aalborg University Hospital, intercostal blockades with bupivacaine is used as standard pain treatment for patients undergoing VATS. Adding adjuvants to the blockades may prolong the effect. The aim of this study is to examine if intercostal nerve blockades with liposomal bupivacaine improves postoperative pain management compared to intercostal nerve blockades with bupivacaine hydrochloride.

Conditions

• Postoperative Pain
• Lung Cancer
• Video Assisted Thoracoscopic Surgery
• Blockades Neuromuscular
• Anesthesia, Local

Interventions

Type	Name	Description
DRUG	Liposomal bupivacaine	As prior described
DRUG	Bupivacaine Hydrochloride	As prior described

Timeline

• Start date: 2021-09-15
• Primary completion: 2022-04-01
• Completion: 2022-05-31
• First posted: 2021-09-08
• Last updated: 2021-09-21

Locations

1 site across 1 country: Denmark