NCT03677778

Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper extremity surgeries. This type of block can unmask underlying respiratory issues such as shortness of breath due to a well-known and typically insignificant side effect of temporary diaphragmatic paralysis. The nerve block may be able to use saline solution to wash out the local anesthetic and potentially reverse this respiratory side effect. Specifically, the goal of this study is to determine if the injection of saline through the nerve block catheter reverses blockade of the phrenic nerve supplying the diaphragm, without affecting the ability of the nerve block to provide pain control after surgery.

Conditions

• Anesthesia, Local
• Phrenic Nerve Paralysis
• Upper Extremity Injury
• Phrenic Nerve Palsy on the Left
• Phrenic Nerve Palsy on the Right

Interventions

Type	Name	Description
PROCEDURE	Normal saline injected via interscalene nerve catheter	With the catheter covered, treatment group patients will receive a normal saline (NS) bolus regimen (30cc 0.9% NS) via their interscalene nerve block catheter.
OTHER	Placebo	With the catheter covered, placebo group patients will go through the same steps as the treatment group, but no solution will be injected into the interscalene nerve block catheter.

Timeline

• Start date: 2018-10-22
• Primary completion: 2022-07-07
• Completion: 2022-07-07
• First posted: 2018-09-19
• Last updated: 2022-08-02

Locations

1 site across 1 country: United States