Clinical Trials Directory

Trials / Completed

CompletedNCT04498923

Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants

Duration of Blockade of Peripheral Nerves With Low Concentrated Bupivacaine Solution Depending of the Adjuvants

Status
Completed
Phase
—
Study type
Observational
Enrollment
68 (actual)
Sponsor
Lviv National Medical University · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.

Detailed description

Peripheral nerve plexuses blocks are performing as a component of analgesia in patients undergoing orthopedic surgery on the upper or lower extremities. Patients are divided into two groups depending on the adjuvant to the local anesthetic: 1st group - patients whose blockade is performed with a solution of bupivacaine 0.375% together with dexamethasone 0.02%; Group 2 - patients whose blockade is performed with a solution of bupivacaine 0.375% together with dexamethasone 0.02% and epinephrine 0.00018%. The duration of the blockade is estimated by puncturing the skin with a needle. The intensity of pain is assessed at 6, 12, 24 and 36 hours after blockade using Visual analog scale (VAS). The amount of narcotic anesthetic used in the postoperative period is also recorded. In addition, patients underwent electromyography of the innervation area of the blocked nerve before the surgery and 24 and 36 hours after surgery.

Conditions

Interventions

TypeNameDescription
DRUGBupivacaine, dexamethasone, epinephrineBupivacaine 75 mg, dexamethasone 4 mg, epinephrine 0,18 mg

Timeline

Start date
2018-01-01
Primary completion
2022-04-05
Completion
2022-04-05
First posted
2020-08-05
Last updated
2022-04-13

Locations

1 site across 1 country: Ukraine

Source: ClinicalTrials.gov record NCT04498923. Inclusion in this directory is not an endorsement.