NCT03149783

Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores

A Randomized Controlled Trial to Determine if Pre- and Post- Operative Regional Pain Control (Transversus Abdominis Plane Block) With Ropivacaine Versus Placebo Leads to Lower Anesthetic and Narcotic Dosing, and Alters Pain Scores

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

A randomized controlled trial to determine if pre- and post- operative regional pain control (transversus abdominis plane block) with ropivacaine versus placebo leads to lower anesthetic and narcotic dosing, and alters pain scores. This study plans to learn more about regional anesthesia and pain control during abdominal surgery. The study will gather data about the effectiveness of continuous catheter infusion of local anesthetic after an abdominal operation. Outcomes include pain scores, IV pain medicine requirements, and delirium.

Conditions

• Pain, Postoperative
• Delirium
• Anesthesia, Local

Interventions

Type	Name	Description
DRUG	Ropivacaine HCL	Ropivacaine injected after placement of catheters, then infused during the operation
DRUG	sodium chloride	Placebo

Timeline

• Start date: 2018-02-13
• Primary completion: 2021-08-31
• Completion: 2021-10-31
• First posted: 2017-05-11
• Last updated: 2021-05-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study