| Not Yet Recruiting | Post-surgical Delirium in Patients Undergoing Radical Cystectomy. NCT03806439 | University of Alexandria | — |
| Not Yet Recruiting | Post-surgical Delirium in Patients Undergoing Open Heart Surgery. NCT03806413 | University of Alexandria | — |
| Suspended | Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks NCT06038136 | Medical University of South Carolina | N/A |
| Not Yet Recruiting | Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle NCT06824077 | University of Alberta | EARLY_Phase 1 |
| Not Yet Recruiting | Bedside Bike Early Mobilization Program for Inpatients NCT07281638 | Indiana University | N/A |
| Not Yet Recruiting | EEG-TMS for Postoperative Delirium After Cardiac Surgery NCT07537725 | RenJi Hospital | N/A |
| Not Yet Recruiting | Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients NCT07407400 | Mahidol University | Phase 4 |
| Recruiting | Fecal Microbiota Transplantation for the Treatment of ICU Delirium NCT07348471 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | N/A |
| Recruiting | Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care NCT07137949 | Boston Medical Center | N/A |
| Recruiting | Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery NCT06969287 | Washington University School of Medicine | Phase 3 |
| Not Yet Recruiting | A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of Gastrodin Inject NCT07422142 | Kunming Pharmaceuticals, Inc. | Phase 1 |
| Recruiting | Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit NCT07369258 | HOSPITAL BRITANICO DE BUENOS AIRES | N/A |
| Not Yet Recruiting | Research on the Development and Validation of an Early Prediction Model for Delirium NCT07337356 | Ruijin Hospital | — |
| Recruiting | Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures NCT07488468 | University of Giessen | — |
| Not Yet Recruiting | Remimazolam vs Midazolam to Reduce Delirium in Adults ≥65 Undergoing CPB Valve Surgery NCT07265128 | Yonsei University | Phase 4 |
| Not Yet Recruiting | Effects of Artificial Intelligence Nurse Orientation Program on Psychological Outcomes and Length of Hospital NCT07171944 | Koç University | N/A |
| Not Yet Recruiting | Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients NCT06468436 | Peking University First Hospital | N/A |
| Recruiting | Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients NCT07151716 | Peking University First Hospital | Phase 4 |
| Recruiting | TaVNS for Delirium NCT07258082 | Stony Brook University | N/A |
| Recruiting | Effect of a Virtual Reality Program on Patient Comfort in the Surgical Intensive Care Unit NCT06830369 | Centre Hospitalier Universitaire, Amiens | N/A |
| Not Yet Recruiting | Sedation and Analgesia Bundled Strategies Among ICU Nurses NCT07132450 | Ruijin Hospital | — |
| Recruiting | Development and Validation of Delirium Recognition Using Computer Vision in Neuro-critical Patients NCT07136207 | Beijing Tiantan Hospital | — |
| Recruiting | VoiceLove Digital Therapy for Delirium in the ICU NCT07218484 | The Methodist Hospital Research Institute | N/A |
| Not Yet Recruiting | Delirium and Cognitive Impairment Development in Hospitalized Older Adults Under Isolation Conditions NCT07114458 | Universitätsklinikum Hamburg-Eppendorf | — |
| Not Yet Recruiting | Patient- and Family-centred Care in the Adult Intensive Care Unit: a Feasibility Study NCT06974214 | Herlev Hospital | N/A |
| Not Yet Recruiting | Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain NCT06993194 | Benha University | N/A |
| Not Yet Recruiting | Stanford-Lucidify EEG Delirium Study NCT06999967 | Stanford University | — |
| Not Yet Recruiting | ABCDEF Bundle to Prevent Delirium for COPD Patients NCT06974318 | Istanbul Saglik Bilimleri University | N/A |
| Recruiting | Intraoperative Midazolam on Delirium Outcome of Elderly Patients NCT06963112 | Chinese PLA General Hospital | Phase 1 |
| Not Yet Recruiting | Effects of Nonpharmacological Interventions in Sleep Quality, Anxiety, and Delirium for Patients of Adult Inte NCT06774599 | Chiayi Christian Hospital | N/A |
| Not Yet Recruiting | RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) NCT05085808 | University of Southern California | Phase 4 |
| Withdrawn | Suvorexant for Insomnia to Prevent Delirium in Hospitalized Cancer Patients NCT06834386 | Mayo Clinic | Phase 4 |
| Not Yet Recruiting | CURATE.Dtx as a Diagnostic and Management Tool for Delirium NCT06240897 | Institute for Digital Medicine (WisDM) | N/A |
| Recruiting | Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II) NCT06192615 | Massachusetts General Hospital | Phase 3 |
| Recruiting | A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors NCT06411561 | University of Washington | N/A |
| Recruiting | Simultaneous Recumbent Cycling and Cognitive Training NCT04556227 | University of Missouri, Kansas City | N/A |
| Recruiting | Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip Replacement NCT06579001 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 4 |
| Not Yet Recruiting | Music for Surgical Intensive Care (MUSIC) NCT06657040 | D'Or Institute for Research and Education | N/A |
| Completed | With the Development of Research, New Algorithms and Technologies Have Emerged, One of Which is Machine Learni NCT07121309 | Second Affiliated Hospital of Soochow University | — |
| Completed | Therapeutic Touch on Pain, Delirium, Sleep, and Physiological Parameters NCT07404904 | Sibel Oksuz | N/A |
| Recruiting | Light and Noise: Objectively Assessing Environmental Risk Factors for Delirium in the ICU NCT06294158 | Medical University of Graz | — |
| Recruiting | Comparative Analysis of Delirium in Older Adults Treated With Ceftazidime, Cefepime, or Ceftriaxone NCT07026253 | Alexandria University | — |
| Recruiting | The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients NCT06509191 | Sultan Qaboos University | Phase 2 / Phase 3 |
| Enrolling By Invitation | The Trajectory and Influencing Factors of Cognitive Level in ICU Delirium Patients After Transfer Out of the I NCT06674603 | Zunyi Medical College | — |
| Recruiting | Transcranial Alternating Current Stimulation on Patients with Delirium and Critical Illness (DeliTACS) NCT06460363 | Kuopio University Hospital | N/A |
| Not Yet Recruiting | Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients NCT06206473 | University Hospital, Toulouse | N/A |
| Not Yet Recruiting | DeliKet (Substudy of KetoNiFast Study ID 22-1398_1) NCT06535022 | University Hospital of Cologne | N/A |
| Not Yet Recruiting | Occupational Therapy Intervention on the Prevention of Delirium and Occupational Performance Status in Elderly NCT06479031 | Hospital Sirio-Libanes | N/A |
| Recruiting | Neurosteer Bedside Monitoring System NCT06718764 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Behavioral Economic & Staffing Strategies in the ICU NCT06184945 | University of Nebraska | N/A |
| Recruiting | Anticoagulation and Inflammation Monitoring in Patients After Heart and Vascular Interventions NCT06222866 | Medical University Innsbruck | — |
| Not Yet Recruiting | Delirium Prevention Guideline for Intensive Care Patients NCT06403410 | Istanbul Demiroglu Bilim University | N/A |
| Recruiting | Modifying the Inpatient Environment to Reduce Delirium in Older Adults NCT06736951 | Farhaan S. Vahidy | N/A |
| Recruiting | Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term NCT06256354 | Peking University First Hospital | N/A |
| Recruiting | Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery NCT06268080 | Auckland City Hospital | N/A |
| Recruiting | DEliriuM in STroke: the Link Between Stroke, Delirium and Long-term Cognitive Impairment NCT06650436 | Universitair Ziekenhuis Brussel | — |
| Completed | Stanford ICU Delirium PIPRA Study NCT06519890 | Stanford University | — |
| Completed | Stanford PIPRA Validation Study in an Elderly Orthopedic Population NCT06567574 | Stanford University | — |
| Recruiting | Delirium Treatment With Transcranial Electrical Stimulation NCT06285721 | A.J.C. Slooter | N/A |
| Recruiting | Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Depart NCT06326424 | Ohio State University | — |
| Recruiting | Researching Efficient Approaches to Delirium Identification-Sustaining Effective Translation NCT05915377 | Penn State University | N/A |
| Completed | Music Therapy to Prevent Hospital-acquired Delirium in Parkinson's Disease and Dementia With Lewy Bodies NCT06063161 | University of Massachusetts, Worcester | N/A |
| Completed | Early Delirium Prediction Via Serial EEG Trajectories and Machine Learning NCT07536854 | Ajou University School of Medicine | — |
| Recruiting | Delirium Phenotypes and Subsequent Impairment During Transition From ICU to Hospital Wards NCT07193797 | Shanghai Zhongshan Hospital | — |
| Recruiting | Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibili NCT06150339 | University Health Network, Toronto | N/A |
| Completed | Eyecontrol coMmunication Platform for dEliRium manaGemEnt in Intensive Care Units (EMERGE) NCT06029244 | Beth Israel Deaconess Medical Center | N/A |
| Completed | Perioperative Salivary Alpha-amylase as a Predictor of Delirium After Lower Extremity Vascular Bypass Surgery NCT06242275 | Tanta University | — |
| Completed | pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS NCT06019078 | Fraser Health | — |
| Completed | Assessing the Effects of Robotic Pets on Patients With Dementia in the Acute Care Hospital Setting NCT06683443 | Sarasota Memorial Health Care System | N/A |
| Recruiting | Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion NCT05461092 | University of Iowa | EARLY_Phase 1 |
| Unknown | The Effect of Clonidine-enhanced Sedation on Delirium in Ventilated Critically Ill Patients NCT01876355 | Deventer Ziekenhuis | Phase 3 |
| Unknown | Care Bundle's Impact on Delirium Prevention in CABG Patients NCT06036017 | İslam Elagöz | N/A |
| Unknown | DELIRIUM SCREENING, INCIDENCE AND MANAGEMENT OBSERVATIONAL STUDY IN 2024 - THE CZECH REPUBLIC NCT05841368 | Brno University Hospital | — |
| Unknown | Using SMART HOME Strategy to Reduce the Incidence of Delirium in the Intensive Care Unit NCT06030453 | National Taiwan University Hospital | N/A |
| Not Yet Recruiting | Effectiveness of a Virtual Reality-Based Sensory Stimulation Intervention in Preventing Delirium in Intensive NCT06153472 | Chinese University of Hong Kong | N/A |
| Recruiting | VR Interventions to Reduce the Prevalence of Delirium in ICU Patients NCT05525702 | Peking Union Medical College Hospital | N/A |
| Completed | Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients NCT06232317 | The Methodist Hospital Research Institute | N/A |
| Recruiting | Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders NCT05929703 | University of Michigan | N/A |
| Enrolling By Invitation | Combined Activity and Cognitive Intervention for ICU Survivors NCT06117761 | The University of Hong Kong | N/A |
| Recruiting | Electroencephalography and Sleep Quality With Lormetazepam in the Intensive Care Unit NCT06473415 | Charite University, Berlin, Germany | — |
| Active Not Recruiting | Family Integration in Therapy Activities in the Intensive Care Unit: The FIT-ICU Feasibility Study NCT06071793 | St. Joseph's Healthcare Hamilton | N/A |
| Completed | Effect of Early Cognitive Stimulation Interventions on Delirium Among Critically Ill Patients NCT06115863 | Damanhour University | N/A |
| Unknown | Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium NCT06076668 | Tanta University | N/A |
| Withdrawn | Evaluating the Role of Pre-existing Resolvins in the Resolution of ICU Delirium NCT04575753 | Université Libre de Bruxelles | — |
| Completed | Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium NCT06161480 | Virginia Commonwealth University | N/A |
| Withdrawn | Noninvasive Transcutaneous Vagal Nerve Stimulation (tcVNS) for Neuromodulating the Conscious State NCT07191340 | Northwestern University | N/A |
| Completed | Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology NCT06334796 | Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia | EARLY_Phase 1 |
| Recruiting | CTSN Embolic Protection Trial NCT06027788 | Icahn School of Medicine at Mount Sinai | N/A |
| Active Not Recruiting | Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors NCT05999903 | Baylor Research Institute | — |
| Recruiting | Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients NCT06176144 | West China Hospital | N/A |
| Recruiting | Delirium in the (Neuro)Intensive/Critical Care in the Adult and Paediatric Czech Populations NCT05891873 | Masaryk University | — |
| Recruiting | Exploring of Serum Biomarkers of Delirium After Cardiovascular Surgery NCT06007755 | Huazhong University of Science and Technology | — |
| Unknown | Prediction Model of Long-term Cognitive Dysfunction and Delirium After Cardiac Surgery NCT05972057 | RenJi Hospital | — |
| Completed | Feasibility of an App to Measure Patient Stressors in an Intensive Care Unit (ICU Feel Better App)- a Before-a NCT04880967 | Charite University, Berlin, Germany | — |
| Unknown | Turkish Precision Anaesthesia Study Project NCT05872529 | Istanbul University | N/A |
| Terminated | Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients NCT05834569 | Korea University Guro Hospital | Phase 4 |
| Unknown | IV Acetaminophen After Cardiac Surgery - PILOT NCT05246644 | McGill University Health Centre/Research Institute of the McGill University Health Centre | Phase 3 |
| Recruiting | Retrospective Evaluation of Delirium Data From Previous Study Patients for Studies at the Clinic for Anesthesi NCT05913531 | Charite University, Berlin, Germany | — |
| Unknown | Psychosocial Nursing Interventions on Sleep, Anxiety and Delirium in Patients Undergoing Open Heart Surgery NCT05864482 | Mersin University | N/A |
| Recruiting | Use of Pupillometry for Pain Assessment in ICU Patients with Delirium NCT05811208 | St. Anne's University Hospital Brno, Czech Republic | — |
| Unknown | Delirium Detection During Routine Patient Care NCT05836714 | Bnai Zion Medical Center | — |
| Recruiting | Trazodone vs. Quetiapine for the Treatment of ICU Delirium NCT05307003 | University of Southern California | — |
| Recruiting | Delirium Reduction With Ramelteon NCT05069428 | Centennial Medical Center | Phase 4 |
| Completed | Effect of Auditory Stimulation by Family Voices in Preventing Delirium: A Randomized Controlled Trial NCT05732584 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Unknown | Dexmedetomidine vs Ketofol on Delirium in Children Undergoing Congenital Inguinal Hernia Repair NCT05786833 | Tanta University | N/A |
| Recruiting | Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project NCT05649800 | University of Leicester | — |
| Completed | Quetiapine in Prevention of Delirium NCT05793632 | Ain Shams University | Phase 2 |
| Completed | Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium NCT06187389 | Kilis 7 Aralik University | — |
| Completed | Implementation Outcome Assessments of the Emergency Department Delirium Screening and Detection Program NCT05606328 | Northwell Health | N/A |
| Withdrawn | Dexmedetomidine Cycling and Sleep in the Pediatric ICU NCT05003102 | Vanderbilt University Medical Center | Phase 4 |
| Recruiting | Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivors NCT05373017 | University of Wisconsin, Madison | N/A |
| Active Not Recruiting | Delayed IntraCranial Hemorrhage in Oral AntiCoagulant Treated Patients With Mild Traumatic Brain Injury NCT07195760 | Bispebjerg Hospital | — |
| Recruiting | Melatonin for Treatment of Delirium in Critically Ill Adult Patients NCT05713877 | Ciusss de L'Est de l'Île de Montréal | Phase 2 |
| Recruiting | Automating Delirium Severity in the ICU NCT06172491 | Mayo Clinic | — |
| Completed | Sight and Hearing Investigation Into Effects on Delirium NCT06176625 | Johns Hopkins University | — |
| Completed | Optimizing Cerebral Autoregulation During Surgery NCT05308290 | Johns Hopkins University | N/A |
| Active Not Recruiting | Biomarkers Associated With Postoperative Cognitive Dysfunction NCT05464355 | University of Oxford | — |
| Active Not Recruiting | The Impact of Non-motor Symptom on the Outcome of Stroke Subjects NCT06854497 | Chiayi Christian Hospital | — |
| Completed | Pregabalin Versus Dexmedetomidine for Delirium Prevention After Cardiac Surgery NCT05640479 | Tanta University | Phase 4 |
| Unknown | Quetiapine as Prophylaxis for Delirium in CABG NCT05801289 | Ain Shams University | N/A |
| Completed | Determining the Preliminary Efficacy of the Emergency Department Delirium Screening and Detection Program NCT05638945 | Northwell Health | N/A |
| Recruiting | Wearable Sensors for Delirium Detection at an Early Stage (WeSen_delirium) NCT05677646 | University of Zurich | — |
| Completed | Prevalence and Recognition of Cognitive Impairment in Hospitalized Patients: a Flash Mob Study NCT05395559 | University Medical Center Groningen | — |
| Completed | Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Pe NCT06504251 | Mahidol University | — |
| Unknown | Study on Biomarkers of Postoperative Delirium in Elderly Cardiac Surgery Patients NCT06194474 | Jining First People's Hospital | — |
| Completed | CONFOCAL-2 Interventional Pilot Study NCT07296029 | Queen's University | Phase 1 / Phase 2 |
| Recruiting | Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy NCT05431595 | M.D. Anderson Cancer Center | Phase 2 / Phase 3 |
| Completed | The ABCDEF Bundle in Critical Care: a French National Survey Still a Long Way to go! NCT06344013 | University Hospital, Brest | — |
| Completed | Remote Cognitive Assessment for Surgical Patients NCT05566275 | University of California, San Francisco | — |
| Unknown | Combination of Music and Relaxing Light on the Patient's Anxiety After Cardiac Surgery in the Intensive Care U NCT05178680 | Poitiers University Hospital | N/A |
| Completed | Evaluation of Quality Indicators on Analgesia, Sedation and Delirium in Intensive Care Patients and Their Impa NCT05384613 | Charite University, Berlin, Germany | — |
| Completed | Nurses' Knowledge, Barriers and Practices in the Assessment of Delirium in the Intensive Care Unit NCT05384964 | Medical University of Gdansk | — |
| Unknown | Safety and Efficacy Evaluation of S (+) - Ketamine in Children NCT04834427 | Chinese PLA General Hospital | Phase 4 |
| Active Not Recruiting | PupillOmetry for Prediction of DelirIUM NCT05248035 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery. NCT03324867 | McGill University Health Centre/Research Institute of the McGill University Health Centre | N/A |
| Recruiting | Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies NCT05195034 | Beijing Tiantan Hospital | N/A |
| Completed | Validation of the 3D-CAM and the UB-CAM in French NCT05242887 | Hospices Civils de Lyon | — |
| Completed | Effect of Neoadjuvant Anti-PD-1 Immunotherapy on Perioperative Analgesia and Postoperative Delirium NCT05273827 | Tianjin Medical University Cancer Institute and Hospital | — |
| Completed | The EARLY DELTA Trial NCT05403268 | Thomas Ottens | N/A |
| Completed | Delirium and EuroSCORE II in Cardiac Surgery NCT05218720 | Aga Khan University | — |
| Unknown | CogMe for the Prevention and Early Detection of Delirium NCT05311761 | Rambam Health Care Campus | N/A |
| Completed | Delirium Related to Proton Pump Inhibitors Use NCT05815550 | University Hospital, Caen | — |
| Unknown | Effect of Ultrasound-guided H-FICB in Patients Undergoing Arthroscopic Knee Surgery NCT05325827 | Affiliated Hospital of Nantong University | N/A |
| Completed | Use of Near Infrared Spectroscopy (NIRS) as a Biomarker of Delirium in Hospitalized Older Adults Doing Physica NCT05442892 | Fundacion Miguel Servet | N/A |
| Completed | A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults NCT03972384 | Ohio State University | N/A |
| Recruiting | Dexmedetomidine or Clonidine Infusion for Prevention of Delirium After Open Heart Surgery NCT05029050 | Oslo University Hospital | Phase 4 |
| Completed | Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement) NCT05209555 | Catharina Ziekenhuis Eindhoven | — |
| Unknown | Association Between Prescription of Antidepressants and Delirium in the Elderly : Analysis From the World Heal NCT05356078 | University Hospital, Caen | — |
| Completed | The Relationship Between Fasting Time and Delirium NCT05567718 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Completed | External Validation of Delirium Prediction Models for Intensive Care Patients NCT05084482 | Zealand University Hospital | — |
| Suspended | Improve the Patients' Recovery With Family- Caregivers to End Delirium NCT05118867 | Mayo Clinic | N/A |
| Recruiting | Redesigning the Surgical Pathway (PROMoTE) NCT05114876 | Sunnybrook Health Sciences Centre | N/A |
| Recruiting | Family Caregiver Role in Decreasing Delirium in Older Patients With Fractured Femur Using HELP Principles. NCT05321771 | Rambam Health Care Campus | N/A |
| Recruiting | Ceribell Delirium Data Collection Study NCT04962815 | Ceribell Inc. | — |
| Unknown | Effect of Intranasal Insulin on POCD and POD NCT03415061 | Hiroaki Sato, MD., PhD. | N/A |
| Completed | Effects of Scenario-based Education Initiative and OSCE for Recognition and Management of Delirium NCT05623475 | Taipei Medical University | N/A |
| Completed | Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery NCT06603129 | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | — |
| Terminated | Description of Therapy Options and Successes in the Long-term Course of Delirium in the Recovery Room - CESARO NCT04920734 | Charite University, Berlin, Germany | — |
| Unknown | Impact of Postanesthesia Care Unit Delirium on Postoperative Quality of Recovery NCT04733703 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Goal-directed Mobilization of Medical Inpatients NCT04760392 | Insel Gruppe AG, University Hospital Bern | N/A |
| Unknown | Comparing Haloperidol and Olanzapine in Treating Terminal Delirium NCT04750395 | HCA Hospice Care | Phase 2 |
| Completed | Physical Restraint of Critically Ill Patients NCT04771793 | Meir Medical Center | — |
| Unknown | Pediatric Delirium Screening in the PICU Via EEG NCT04846023 | St. Justine's Hospital | N/A |
| Unknown | Family Assessment of Pediatric Delirium NCT05220761 | University of Calgary | — |
| Unknown | The Effectiveness of Acupuncture for Complications in Critically Ill Patients NCT04950738 | China Medical University Hospital | N/A |
| Withdrawn | Cognitive Function and Health-related Quality of Life After Neuro-intensive Care NCT04881097 | Rigshospitalet, Denmark | — |
| Unknown | A Software to Prevent Delirium (PREVEDEL) in Hospitalized Older Adults NCT05108207 | University of Chile | N/A |
| Active Not Recruiting | Delirium in Children Undergoing Stem Cell Transplantation NCT04937400 | Weill Medical College of Cornell University | — |
| Unknown | Nursing Intervention to Reduce Incidence and Duration of Delirium in Patients in Intensive Care NCT05172583 | Universidad Surcolombiana | N/A |
| Unknown | MDD(Mild Cognitive Impairment Delirium Dementia) Cohort NCT05113446 | Keimyung University Dongsan Medical Center | — |
| Completed | Projection of Visual Material on Postoperative Delirium in Patients Undergoing Cardiac Surgery NCT05932394 | University of Huelva | N/A |
| Recruiting | Perioperative EEG-Monitoring and Postoperative Delirium in Patients Undergoing Cardiovascular Surgery NCT04832568 | Huazhong University of Science and Technology | — |
| Completed | Management of PADIS in Emergency Intensive Care Unit NCT06339385 | Capital Medical University | — |
| Completed | Neurotropism and Neuroinflammation in COVID-19 Patients With Delirium. NCT04785157 | University Hospital, Toulouse | — |
| Terminated | Low-Dose Dexmedetomidine for Delirium Prevention in Mechanically Ventilated Septic Patients NCT04876937 | Peking University First Hospital | N/A |
| Recruiting | Pervasive Sensing and AI in Intelligent ICU NCT05127265 | University of Florida | — |
| Unknown | The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy NCT04953767 | Chang Gung Memorial Hospital | N/A |
| Recruiting | Goal-Directed Sedation in Mechanically Ventilated Infants and Children NCT04801589 | Vanderbilt University Medical Center | Phase 3 |
| Completed | Maximizing trEatment of Neurological Dysfunction Using INtravenous Guanfacine Study NCT04742673 | Vanderbilt University Medical Center | Phase 2 |
| Completed | Post-operative Delirium (POD) in Patients Undergoing Hip Fracture Surgery NCT05105906 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Terminated | Improved Patient Safety for Acute Restless Medical Patients With Supplemental Observation NCT04841122 | Aalborg University Hospital | N/A |
| Unknown | Validation of the 3D-CAM Turkish Version NCT04853706 | Aydin Adnan Menderes University | N/A |
| Completed | HD-Tdcs and Pharmacological Intervention For Delirium In Critical Patients With COVID-19 NCT05963958 | Suellen Andrade | N/A |
| Suspended | Virtual Reality to Reduce Delirium NCT04498585 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Use of a Novel Digital Therapeutic Intervention for the Management of Delirium in the Acute Care Environment NCT04652622 | Fraser Health | N/A |
| Completed | Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department NCT04846322 | Yale University | — |
| Withdrawn | Post Operative Delirium Study NCT04635774 | University of Kansas Medical Center | Phase 1 / Phase 2 |
| Withdrawn | Study of BXCL501 In Agitation Associated With Delirium in ICU Patients NCT05313386 | BioXcel Therapeutics Inc | Phase 2 |
| Completed | Early Cognitive Intervention in Delirium NCT04740567 | Vanderbilt University Medical Center | N/A |
| Recruiting | Impact of Remimazolam on Prognosis After Bladder Cancer Surgery NCT04532606 | Peking University First Hospital | Phase 4 |
| Unknown | Clonidine vs. Dexmedetomidine in Agitated Delirium in Intensive Care Patients NCT04758936 | Erasme University Hospital | Phase 4 |
| Unknown | Relationship Between Delirium Severity by CAM-ICU 7 and 4C Mortality Score of the COVID-19 Patients in ICU NCT04812041 | Ankara City Hospital Bilkent | — |
| Recruiting | Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury NCT04722939 | Dr. Gordon Boyd | — |
| Completed | Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection NCT07167628 | China Medical University Hospital | — |
| Unknown | Postoperative Delirium in Cardiac Surgery ICU NCT04527341 | Shanghai Zhongshan Hospital | — |
| Unknown | Non-Invasive Eye Tracking for the Diagnosis of Delirium on ICU NCT04589169 | Chelsea and Westminster NHS Foundation Trust | — |
| Completed | The Effect of Guanfacine on Delirium in Critically Ill Patients NCT04578886 | University of Alabama at Birmingham | Phase 3 |
| Recruiting | Nocturnal Hypoxia in Geriatric Patients After Hip Fracture NCT04007432 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Efficacy and Safety of Suvorexant (MK-4305) for Reducing Incidence of Delirium in Japanese Participants at Hig NCT04571944 | Merck Sharp & Dohme LLC | Phase 3 |
| Unknown | WHO Covid 19 - Neurological Abnormalities in SARS-CoV-2 ICU Patients NCT04643548 | University Hospital, Clermont-Ferrand | — |
| Active Not Recruiting | SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty NCT04247646 | Scripps Health | N/A |
| Completed | Post-ICU Follow-up Study in Covid-19 Patients NCT05299346 | Sahlgrenska University Hospital | — |
| Unknown | The Effect of Music on Delirium, Pain, Need of Sedation, Anxiety and Vital Parameters NCT05082623 | Ege University | N/A |
| Unknown | Different Anesthetic Strategies on Postoperative Cognitive Function and Delirium in Patients Undergoing Cardia NCT04505059 | China National Center for Cardiovascular Diseases | N/A |
| Completed | Delirium Screening 3 Methods Study NCT04551508 | Hospitalsenheden Vest | — |
| Unknown | Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and St NCT04538469 | University of Glasgow | — |
| Completed | PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in NCT04093219 | Beth Israel Deaconess Medical Center | Phase 3 |
| Terminated | Alteration of Blood-Brain-Barrier Permeability at Loss of Consciousness in Delirious Patients Recorded With Di NCT04320082 | Charite University, Berlin, Germany | — |
| Unknown | Study to Assess and Monitor Brain Activity NCT04602988 | Massachusetts General Hospital | — |
| Completed | Neurocognitive Impairment in Pediatric Patients With Meningoencephalitis and Sepsis-associated Encephalopathy NCT04467762 | University of Rostock | — |
| Unknown | A Study on Noise Exposure Status and the Effect of Noise Management in Pediatric Intensive Care Unit NCT04544085 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | N/A |
| Unknown | MusiC to Prevent deliriUm During neuroSurgerY NCT04649450 | Erasmus Medical Center | N/A |
| Completed | The Efficacy of Oral Melatonin in Preventing Postoperative Delirium for Patients Undergoing Orthopedic Surgery NCT05236907 | University of Baghdad | N/A |
| Unknown | Tight End-tidal Gas Control During Anesthesia to Decrease Postoperative Delirium Anesthetic Management NCT04406350 | University of Manitoba | N/A |
| Completed | Hypertension and Controlled Hypotension in the Elderly NCT04433416 | Zhang Lei | — |
| Completed | Assessment of Postoperative Delirium With CAM ICU Score in Patients Treated With Serotoninergic Reuptake (SSRI NCT05089097 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | — |
| Withdrawn | Dexmedetomidine Sublingual Film for the Management of Agitation in Delirium: Safety and Preliminary Efficacy NCT04382170 | Jeff C. Huffman, MD | Phase 2 |
| Completed | Does Rocking Charis Calm Delirious Patients in the Intensive Care Unit NCT04401514 | Scandinavian Critical Care Trials Group | N/A |
| Unknown | Effect of Preoperative Intervention With Folic Acid and Vitamin B12 on Postoperative Neurobehavioral Changes i NCT04456985 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | N/A |
| Completed | Neurocognitive Impairment in Patients With COVID-19 NCT04359914 | University of Rostock | — |
| Completed | Assessment and Management of Pain, Agitation, Delirium and Sleep Deprivation (PADS) in ICU by PADS Protocol, T NCT04270331 | Mahidol University | N/A |
| Unknown | The Effectiveness of Acupuncture for Delirium in Critically Ill Patients NCT04312893 | China Medical University Hospital | N/A |
| Unknown | Sleep and Cognition After Ambulatory Hip and Knee Arthroplasty NCT04227873 | Hvidovre University Hospital | — |
| Recruiting | Perioperative Longitudinal Study of Complications and Long-term Outcomes NCT05331118 | UMC Utrecht | — |
| Unknown | Using Eye Mask and Earplugs on Prevention of Delirium NCT05000476 | Baskent University | N/A |
| Completed | Thiamine Administration and Prevalence of Delirium in the Intensive Care Unit: A Before-after Study NCT04214106 | Meir Medical Center | — |
| Terminated | Impact of Alarm Reduction on Delirium in ICU NCT04246892 | Central Hospital, Nancy, France | — |
| Completed | Ketamine Infusion as Sedative Analgesic in Severe ARDS NCT04818827 | Interfaith Medical Center | — |
| Completed | Effect of Minocycline on Delirium Incidence in Critically Ill Patients NCT04219735 | Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude | Phase 2 |
| Withdrawn | Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts NCT04249141 | Ohio State University | — |
| Unknown | Trial of a Non-pharmacological Intervention to Prevent Delirium Among Elderly In-patients NCT03158909 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Partnering With Family Members to Prevent, Detect and Manage Delirium in Critically Ill Patients. NCT04099472 | University of Calgary | N/A |
| Unknown | Effect of Preoperative Anxiety on Postoperative Delirium in Elderly Patients Undergoing Orthopaedic Surgery. NCT04216615 | Xuzhou Medical University | — |
| Completed | Validation Study of the "CORNELL ASSESSMENT PEDIATRIC DELIRIUM" (CAPD)" Scale in Italian Language NCT04589767 | Azienda Ospedaliera di Padova | — |
| Recruiting | Perioperative EEG-Monitoring and Emergence Delirium in Children NCT04091724 | Huazhong University of Science and Technology | — |
| Recruiting | Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients NCT04289142 | Sunnybrook Health Sciences Centre | Phase 4 |
| Completed | Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR) NCT04007523 | University of Michigan | N/A |
| Completed | Cerebral Monitoring and Post-operative Delirium and Outcomes NCT04643834 | Montreal Heart Institute | — |
| Active Not Recruiting | Benzodiazepine-free Cardiac Anesthesia for Reduction of Postoperative Delirium NCT03928236 | Population Health Research Institute | N/A |
| Completed | Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative Delirium NCT04189666 | Ain Shams University | Phase 1 / Phase 2 |
| Completed | Education for Recognition and Management of Delirium NCT03642249 | Taipei Medical University | N/A |
| Completed | PREdiction of DELIRium in Medical ICU Patients NCT04218461 | Istanbul Demiroglu Bilim University | — |
| Unknown | Prevalence of Auditory Dysfunction and ICU-acquired Delirium Following Cardiac Surgery With Cardiopulmonary By NCT04151914 | European Georges Pompidou Hospital | — |
| Unknown | Estimation of Delirium Data Completeness NCT04084821 | Efficacy Care R&D Ltd | — |
| Completed | Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery NCT05579093 | Columbia University | — |
| Completed | Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit NCT04068311 | Ohio State University | N/A |
| Unknown | Lived Experiences and Impact of Delirium in Critically Ill Children: a Qualitative Study NCT04168515 | McMaster University | — |
| Unknown | Cognition and the Immunology of Postoperative Outcomes NCT04792983 | Brigham and Women's Hospital | — |
| Unknown | EEG Phase Synchrony, Sedation and Delirium in the CVICU NCT04005196 | University of Toronto | — |
| Unknown | ReMindCare App for Patients From First Episode of Psychosis Unit. NCT03807388 | Instituto de Investigacion Sanitaria INCLIVA | N/A |
| Completed | s100β, NSE n GFAP in Living Donor Hepatectomy and Delirium NCT04422925 | Akdeniz University | — |
| Completed | The PATHFINDER Study: A Feasibility Trial NCT04016740 | Beth Israel Deaconess Medical Center | EARLY_Phase 1 |
| Unknown | Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM) NCT03880084 | University of Modena and Reggio Emilia | — |
| Unknown | The Mechanism of Dexmedetomidine in Improving Delirium After Cardiac Surgery NCT04127500 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Active Not Recruiting | Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Ca NCT03743649 | M.D. Anderson Cancer Center | Phase 2 / Phase 3 |
| Completed | Improving Safety of Diagnosis and Therapy in the Inpatient Setting NCT04393909 | Brigham and Women's Hospital | N/A |
| Completed | Guided Occupational Therapist Cognitive Interventions in Critically Ill Patients NCT03604809 | Alberta Health Services, Calgary | N/A |
| Completed | The Effect of Music Therapy on Delirium NCT03980782 | Geisinger Clinic | N/A |
| Unknown | Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture NCT04404959 | Aretaieion University Hospital | N/A |
| Completed | The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU NCT03931070 | Rhode Island Hospital | Phase 4 |
| Unknown | Rehabilitation Intervention on Prevention of Postoperative Delirium NCT03949114 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Post-stroke Delirium Screening NCT03930719 | University Medicine Greifswald | — |
| Active Not Recruiting | Low-dose Dexmedetomidine and Postoperative Delirium After Cardiac Surgery NCT03624595 | Dong-Xin Wang | N/A |
| Withdrawn | Quetiapine Treatment for Pediatric Delirium NCT03572257 | Medical College of Wisconsin | Phase 2 / Phase 3 |
| Unknown | BIS-Guided Sedation in Critically Ill Patients Under Deep Sedation NCT03840577 | Hospital Italiano de Buenos Aires | N/A |
| Unknown | Neuroinflammation During ICU-associated Delirium in Critically Ill Patients and Its Association With Structura NCT04078503 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | — |
| Completed | Rate of Postoperative Delirium and Postoperative Cognitive Dysfunction After Spinal Anesthesia NCT03715244 | Charite University, Berlin, Germany | — |
| Completed | De-escalating Vital Sign Checks NCT04046458 | University of California, San Francisco | N/A |
| Recruiting | Pilot Clinical Trial of an Integrative Intervention to Improve Critically Ill Patients' Delirium and Related O NCT02905812 | University of Alberta | N/A |
| Terminated | Clinical Evaluation Program of DeltaScan (ICU) NCT03735940 | UMC Utrecht | N/A |
| Terminated | Influence of Dexmedetomidine or Propofol on ICU Delirium NCT02807467 | University Hospital, Basel, Switzerland | Phase 4 |
| Suspended | Cognitive Processing in Patients Surviving Delirium. Neuropsychological, EEG and Structural Brain Correlates. NCT03562689 | Rigshospitalet, Denmark | — |
| Completed | DeltaScan Validation Study for the Assessment of Delirium in the ICU and on Wards NCT03966274 | UMC Utrecht | — |
| Completed | Vitamin D Level and Emergence Delirium in Children NCT05076162 | Aydin Adnan Menderes University | — |
| Completed | Delirium Reduction by Volatile Anesthesia in Cardiac Surgery NCT03729011 | Meshalkin Research Institute of Pathology of Circulation | Phase 4 |
| Completed | Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delir NCT03832192 | Victor Wang | Phase 2 |
| Completed | Early Rehabilitation in Critically Ill Children - The PICU Liber8 Study NCT03573479 | McMaster University | — |
| Completed | Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors NCT03967496 | Sultan Qaboos University | — |
| Withdrawn | FAM-CAM Translation and Validation Into German NCT03732443 | Technical University of Munich | — |
| Terminated | Clinical Evaluation Program of DeltaScan (Ward) NCT03735927 | UMC Utrecht | N/A |
| Unknown | Correlation Between Urine UACR and Postoperative Neurocognitive Disorder in Elderly Patients With Non-cardiac NCT03860714 | Han Yuan | — |
| Withdrawn | Delirium Detection in Pediatric Intensive Care Unit Through a French Translation of the CAPD : a French Monoce NCT04954261 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Effects of a Dementia-friendly Program NCT04737733 | University Hospital, Akershus | N/A |
| Completed | Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium NCT03498560 | Massachusetts General Hospital | — |
| Completed | Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit NCT04080557 | Amphia Hospital | — |
| Completed | Delirium Assessment in the Pediatric Intensive Care Unit NCT04041947 | Cukurova University | — |
| Completed | The Use of PARO to Decrease Agitation in Persons With Dementia and/or Delirium NCT05565703 | University of Pennsylvania | N/A |
| Completed | Enhancing European Management of Analgesia, Sedation and Delirium NCT03553719 | Charite University, Berlin, Germany | — |
| Terminated | Identifying Novel Aging Targets for Treatment of Delirium NCT03682874 | Wake Forest University Health Sciences | — |
| Withdrawn | PER3 Clock Gene Polymorphism, Clock Gene Expression and Delirium in the Intensive Care Unit. NCT02673450 | Zealand University Hospital | — |
| Withdrawn | Non-Invasive Brain Stimulation and Delirium NCT03518996 | Gen Shinozaki | N/A |
| Terminated | Speed of Processing Training for Cognitive Deficits After Delirium in Older Adults NCT03342989 | University of Alabama at Birmingham | N/A |
| Active Not Recruiting | Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery NCT03480061 | Sunnybrook Health Sciences Centre | Phase 4 |
| Completed | Earplugs and Eye Masks for Reducing Delirium NCT03471520 | Duke University | N/A |
| Completed | Subsyndromal Delirium in Intensive Care Unit NCT03813459 | Centro Hospitalar Lisboa Ocidental | — |
| Unknown | Incidence of Geriatric Syndromes Overlap NCT03647436 | Hospital de la Ribera | — |
| Completed | Neuronal Damage In Delirium Study NCT03724201 | University of Calgary | — |
| Unknown | Immersive Virtual Reality in Mechanically Ventilated Patients NCT03569358 | Changi General Hospital | N/A |
| Completed | Emergence Delirium in Children for Magnetic Resonance Imaging NCT04816344 | Turkiye Yuksek Ihtisas Education and Research Hospital | — |
| Completed | INCIDENCE OF Delirium After Cardiac SURGERY Surgery NCT04986488 | Shahid Gangalal National Heart Centre | — |