NCT05308290

Optimizing Cerebral Autoregulation During Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 60 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to conduct a pilot trial to determine the feasibility, safety, and potential efficacy of targeting mean arterial blood pressure (MAP) within the limits of cerebral autoregulation during surgery compared with usual care.

Conditions

• Hip Fractures
• Hip Arthropathy
• Surgery
• Delirium

Interventions

Type	Name	Description
OTHER	Blood pressure management according to cerebral autoregulation	Intraoperative blood pressure will be targeted based on limits of cerebral autoregulation.
OTHER	Blood pressure management according to usual care	Intraoperative blood pressure will be targeted based on usual care.

Timeline

• Start date: 2023-01-09
• Primary completion: 2024-06-28
• Completion: 2025-07-30
• First posted: 2022-04-04
• Last updated: 2025-09-02
• Results posted: 2025-07-16

Locations

1 site across 1 country: United States