Trials / Unknown
UnknownNCT04505059
Different Anesthetic Strategies on Postoperative Cognitive Function and Delirium in Patients Undergoing Cardiac Surgery
Effect of Different Anesthetic Strategies on Postoperative Cognitive Function and Delirium in Adult Patients Undergoing Cardiac Surgery
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 502 (estimated)
- Sponsor
- China National Center for Cardiovascular Diseases · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a prospective, multi-center, double-blind, randomized clinical trials.
Detailed description
Prospective randomized multi-center trial involving about 502 subjects will be enrolled in 3 centers. Patients will be randomized to two groups in equal proportion. Investigators set a hypothesis that precision cardiac anesthesia, which involves the modification of several crucial anesthetic modalities, would reduces the incidence of postoperative cognitive function and delirium in patients undergoing cardiac surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Precision cardiac anesthesia | Aperi-operative anesthetic management through target-controlled infusion to accurately control the patient blood concentration, with combination of bispectral index and neuromuscular monitoring to adjust the dosage of general anesthetics. |
| PROCEDURE | Conventional cardiac anesthesia | The anesthesia strategy is mainly depending on the anesthesiologist's clinical experience |
Timeline
- Start date
- 2020-09-11
- Primary completion
- 2022-07-18
- Completion
- 2023-01-18
- First posted
- 2020-08-07
- Last updated
- 2022-03-15
Locations
3 sites across 1 country: China
Source: ClinicalTrials.gov record NCT04505059. Inclusion in this directory is not an endorsement.