NCT03174860

Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success

Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the effect of preoperative Diclofenac Potassium (50 mg Cataflam) on the anesthetic success of buccal infiltration with 4% articaine with epinephrine 1:200,000 in mandibular molars with symptomatic irreversible pulpitis.

Detailed description

This study aims to evaluate the effectiveness of preoperative administration of Diclofenac Potassium (50 mg Cataflam) compared to placebo, one hour before treatment, on the anesthetic success of buccal infiltration with 4% articaine with epinephrine 1:200,000 in mandibular molars with symptomatic irreversible pulpitis. Patients with moderate-to-severe pre-operative pain are selected. Full medical and dental history will be obtained from all patients treated during this study by the operator. Clinical diagnosis of symptomatic irreversible pulpitis is to be confirmed. The primary outcome is success of buccal infiltration using articaine.The secondary outcomes are pain on injection. Patients will be recruited from the outpatient clinic of Endodontics at the Faculty of Oral and Dental Medicine, Cairo University.

Conditions

• Pulpitis - Irreversible
• Anesthesia, Local

Interventions

Type	Name	Description
DRUG	Diclofenac Potassium 50mg Tab	A 50 mg tablet of the medication to be taken one hour before initiation of endodontic treatment.
DRUG	Placebo	A placebo will be taken one hour before initiation of endodontic treatment.

Timeline

• Start date: 2016-10-01
• Primary completion: 2018-02-01
• Completion: 2018-04-01
• First posted: 2017-06-05
• Last updated: 2018-07-19

Locations

1 site across 1 country: Egypt