| Not Yet Recruiting | Observational Cross-sectional Study Aiming to Determine the Correlation Between Pulpal Status and IL-8 and Pre NCT07466095 | Cairo University | — |
| Not Yet Recruiting | Clinical and Radiographic Assessment of Bio C Repair, Biodentine and Mineral Trioxide Aggregate NCT07522723 | Cairo University | N/A |
| Not Yet Recruiting | SCN9A Gene Expression and Inflammatory Cytokines NCT07532200 | Jamia Millia Islamia | — |
| Active Not Recruiting | Effect of Cryotherapy on Postoperative Pain for Pulpotomy NCT07245004 | Sirawut Hiran-us | EARLY_Phase 1 |
| Recruiting | The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Succe NCT07340606 | Misr International University | N/A |
| Not Yet Recruiting | Comparison of Endodontic Flare up in Single Visit Root Canal Treatment Versus Multiple Visit Root Canal Treatm NCT06972433 | College of Physicians and Surgeons Pakistan | N/A |
| Not Yet Recruiting | Comparison of Aquaporin -4, -5, -9 and IL-8 Levels in GCF, Dentin Fluid and Pulp Samples NCT06938191 | Kırıkkale University | — |
| Not Yet Recruiting | Evaluation of Pulpotomy Versus Pulpectomy in Primary Molars With Irreversible Pulpitis or Necrotic Pulp NCT07230717 | Ajman University | N/A |
| Recruiting | Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis NCT07375576 | Mustafa Kemal University | N/A |
| Recruiting | Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France NCT07297836 | University Hospital, Strasbourg, France | — |
| Recruiting | Effect of Menstrual Phase on the Anesthetic Efficacy NCT07306533 | Jamia Millia Islamia | N/A |
| Completed | Can Pretreatment With Analgesics Reduce Postendodontic Pain? NCT07271654 | College of Physicians and Surgeons Pakistan | N/A |
| Completed | Effect of Probiotics, Double Antibiotic Paste, and Calcium Hydroxide on Postoperative Pain in Irreversible Pul NCT07270159 | Dow University of Health Sciences | N/A |
| Completed | Single Gene Polymorphism and the Success Rate of Inferior Alveolar Nerve Block NCT07012382 | Jamia Millia Islamia | N/A |
| Not Yet Recruiting | Outcome of Pulpotomy With MTA and Biodentin in Permanent Teeth With Caries Exposure NCT06913283 | Altamash Institute of Dental Medicine | N/A |
| Active Not Recruiting | The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy NCT07130214 | Ataturk University | — |
| Not Yet Recruiting | Clinical and Radiographic Success of Pulpotomy Using Neoputty Mineral Trioxide Aggregate Versus Pulpectomy Usi NCT06922578 | Cairo University | N/A |
| Active Not Recruiting | Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars NCT06811636 | Çanakkale Onsekiz Mart University | N/A |
| Not Yet Recruiting | Clinical and Radiographic Evaluation of Pulpotomy Using Neoputty MTA Versus Pulpectomy Using Metapex in Vital NCT06929247 | Mohamed Nashaat Mohamed | N/A |
| Completed | The Effect of Dexamethasone in Full Pulpotomy on Postoperative Pain in Permanent Molars NCT07233577 | Cukurova University | N/A |
| Active Not Recruiting | Clinical and Radiographic Evaluation of Propolis As a Hemostatic Agent for Pulpotomy of Mature Permanent Molar NCT06679075 | Misr International University | Phase 2 |
| Completed | The Effect of Prognostic Factors on the Success of Full Pulpotomy in Permanent Mature Molars With Irreversible NCT06597487 | Misr International University | N/A |
| Completed | Assessment of Different Medications in Modifying the Efficacy of Anesthesia in Mandibular Molars With Acute Ir NCT07088042 | Ain Shams University | Phase 4 |
| Completed | Diagnostic Accuracy of Cold, Heat, and Electric Pulp Tests NCT07434622 | Istanbul University | — |
| Active Not Recruiting | Outcomes of Full Pulpotomy Treatment in Teeth With Symptoms of Irreversible Pulpitis NCT06802536 | Firat University | Phase 4 |
| Completed | Cryotherapy Versus Dexamethasone on Postoperative Pain in Permanent Mandibular Molars NCT06832254 | Cukurova University | N/A |
| Completed | Effect of Cryotreated Sodium Hypochlorite Irrigation at Different Consentrations in Mandibular First Molars NCT06820996 | Cukurova University | N/A |
| Completed | Effect of Different Apical Actions on Local Inflammatory Mediators and Pain NCT06760312 | Izmir Katip Celebi University | N/A |
| Recruiting | Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques NCT06573710 | Ain Shams University | N/A |
| Recruiting | Single Rotary File Pulpectomy in Primary Molars NCT06146686 | Cairo University | N/A |
| Recruiting | Zinc Oxide Ozonated Olive Oil in LSTR NCT06854744 | Tanta University | N/A |
| Unknown | Effect of Alcohol Consumption on the Success Rates NCT06201871 | Jamia Millia Islamia | N/A |
| Recruiting | Prognostic Biomarkers for Pulpotomy Outcome NCT06514053 | The University of Hong Kong | N/A |
| Completed | Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis NCT05840913 | Armed Forces Institute of Dentistry, Pakistan | Phase 2 |
| Recruiting | A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Te NCT06438523 | Future University in Egypt | N/A |
| Completed | Effect of Cryotherapy on Postoperative Pain in Vital Pulp Treatment of Molar Teeth NCT06644703 | Cukurova University | N/A |
| Unknown | Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis NCT06002698 | University of Malaya | N/A |
| Unknown | Intraligmentary Dexamethasone in Lower First Molars With Irreversible Pulpitis and Apical Periodontits NCT05928611 | Cairo University | N/A |
| Enrolling By Invitation | Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis NCT05964933 | National University Hospital, Singapore | N/A |
| Completed | Effect of Intrapulpal Injections on the Post-endodontic Pain NCT06088446 | Jamia Millia Islamia | N/A |
| Unknown | Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis NCT05726357 | British University In Egypt | N/A |
| Unknown | Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments NCT05902936 | Cairo University | N/A |
| Completed | Enhancing Anaesthetic Success in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Comparative Rando NCT06330519 | Ain Shams University | Phase 4 |
| Completed | Evaluation of Post-operative Pain After Total Pulpotomy and Root Canal Treatment NCT05923619 | Mustafa Kemal University | N/A |
| Completed | Evaluation of Lesion Sterilization and Tissue Repair Techniques Versus Pulpectomy in Primary Molars With Infla NCT05336682 | Cairo University | N/A |
| Completed | Success of Lesion Sterilization and Tissue Repair Therapy NCT06818578 | Inonu University | Phase 4 |
| Completed | Cryoanalgesia for Irreversible Pulpitis NCT06268912 | Universitat Internacional de Catalunya | N/A |
| Unknown | Outcome Following Endodontic Treatment Using Traditional Access Versus Conservative Access NCT05402098 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Unknown | Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis NCT05406557 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Withdrawn | Endodontic-Restorative Pre-Radiation Therapy of Head and Neck Cancer Patients NCT04996641 | Abramson Cancer Center at Penn Medicine | N/A |
| Unknown | The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in NCT04669392 | Cairo University | EARLY_Phase 1 |
| Completed | Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpoto NCT05853185 | Liaquat University of Medical & Health Sciences | Phase 4 |
| Completed | Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primar NCT05582317 | Suez Canal University | N/A |
| Completed | Vital Pulp Therapy vs. Root Canal Treatment in Mature Teeth With Irreversible Pulpitis NCT07355140 | Universidad Central de Venezuela | N/A |
| Completed | Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer NCT05904184 | University of Medicine and Pharmacy at Ho Chi Minh City | Phase 3 |
| Completed | Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. . NCT04773886 | Maharishi Markendeswar University (Deemed to be University) | Phase 4 |
| Completed | Evaluation of the Effect of Adding Dexamethasone to 2% Lidocaine NCT05361291 | Jamia Millia Islamia | N/A |
| Completed | Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy M NCT04719247 | Ain Shams University | N/A |
| Unknown | Pulpotomy vs.Root Canal Treatment in Managing Irreversible Pulpitis NCT03956199 | King's College London | N/A |
| Completed | Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanen NCT05266859 | Liaquat College of Medicine and Dentistry | Phase 2 |
| Unknown | Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment NCT03916900 | Cairo University | N/A |
| Unknown | Outcome of Pulpotomy Versus Root Canal Therapy NCT05279781 | Jordan University of Science and Technology | N/A |
| Unknown | Comparative Evaluation of Partial and Complete Pulpotomy in Permanent Molars NCT04397315 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Completed | Evaluation of Chitosan Scaffold and Mineral Trioxide Aggregate Pulpotomy in Mature Permanent Molars With Irrev NCT04308863 | Nourhan M.Aly | Phase 2 |
| Unknown | Comparison Between Intraligamentary Piroxicam and Articaine NCT03612323 | Cairo University | EARLY_Phase 1 |
| Unknown | Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars. NCT03553407 | University of Sao Paulo | N/A |
| Unknown | Post Operative Pain of Root Canal Preparation With Wave One and Neolix in Acute Irreversible Pulpitis NCT02952300 | Cairo University | N/A |
| Completed | Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain NCT03341260 | Cairo University | Phase 2 / Phase 3 |
| Unknown | Comparison of a Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine of Post-endodontic Pain NCT03006107 | Cairo University | N/A |
| Unknown | Assessment of Postoperative Pain Using Reciproc Versus One Shape Files in Patients With Irreversible Pulpitis NCT02953912 | Cairo University | N/A |
| Completed | Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success NCT03174860 | Cairo University | Phase 2 / Phase 3 |
| Completed | The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and NCT03116672 | Universidad Autonoma de Baja California | N/A |