NCT06832254

Cryotherapy Versus Dexamethasone on Postoperative Pain in Permanent Mandibular Molars

Effectiveness of Cryotherapy Versus Dexamethasone on Reducing Postoperative Pain in Permanent Mandibular Molars with Irreversible Pulpitis: a Randomized Controlled Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Cukurova University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial was to evaluate cryotherapy versus dexamethasone on the intensity of postoperative pain in root canal treatment procedures in mandibular first molar teeth with symptomatic irreversible pulpitis. The main question it aims to answer is: * Does controlled irrigation with cold saline in root canal treatment reduce the severity of postoperative pain? * Does controlled irrigation with dexamethasone in root canal treatment reduce the severity of postoperative pain? In the cryotherapy group, unlike the control and dexamethasone group, the root canals were irrigated with 2 °C salin solution in final irrigation. In the dexamethasone group, unlike the control and cryotherapy group, the root canals were irrigated with 1 mL dexamethasone solution in final irrigation.

Conditions

• Pulpitis - Irreversible

Interventions

Type	Name	Description
OTHER	Cryotherapy	The root canals were irrigated with 2 °C saline solution in final irrigation in cryotherapy group.
DRUG	Dexamethasone	Each root canal was irrigated with 1 mL dexamethasone solution in final irrigation in dexamethasone group.

Timeline

• Start date: 2024-04-05
• Primary completion: 2024-12-10
• Completion: 2025-01-05
• First posted: 2025-02-18
• Last updated: 2025-03-11

Locations

1 site across 1 country: Turkey (Türkiye)