NCT03341260

Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain

Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess the effect of preoperative a single-dose of 50 mg diclofenac potassium on postoperative endodontic pain in mandibular molars with symptomatic irreversible pulpitis.

Detailed description

Patients with moderate-to-severe preoperative pain are selected. Patients receive either a single-dose of 50 mg diclofenac potassium (group A) or a placebo tablet as a control (group B). All patients receive the assigned premedication one hour before single-visit root canal treatment. Postoperative endodontic pain is measured at the following time points: 6 , 12,24,48 h after treatment. The incidence of analgesic intake is also recorded.

Conditions

• Pulpitis - Irreversible

Interventions

Type	Name	Description
DRUG	Diclofenac Potassium 50mg Tab.	A 50 mg tablet of the medication to be taken one hour before initiation of endodontic treatment.
DRUG	Placebo	A placebo will be taken one hour before initiation of endodontic treatment.

Timeline

• Start date: 2016-12-01
• Primary completion: 2018-02-01
• Completion: 2018-04-01
• First posted: 2017-11-14
• Last updated: 2018-04-09

Locations

1 site across 1 country: Egypt