NCT07233577

The Effect of Dexamethasone in Full Pulpotomy on Postoperative Pain in Permanent Molars

The Effect of Dexamethasone in Full Pulpotomy on Postoperative Pain in Permanent Molars With Symptomatic Irreversible Pulpitis: A Randomized Clinical Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Cukurova University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The goal of this clinical trial is to evaluate the effects of cryotherapy and dexamethasone on the intensity of postoperative pain in full pulpotomy procedures in permanent molars with symptomatic irreversible pulpitis. The main questions it aims to answer are: * Does controlled irrigation with cold saline during full pulpotomy reduce the severity of postoperative pain? * Does controlled irrigation with dexamethasone during full pulpotomy reduce the severity of postoperative pain? In the cryotherapy group, unlike the control and dexamethasone groups, the pulp chamber was irrigated with 2°C saline solution during the final irrigation step. In the dexamethasone group, unlike the control and cryotherapy groups, the pulp chamber was irrigated with 2 mL dexamethasone solution during the final irrigation step.

Conditions

• Pulpitis - Irreversible

Interventions

Type	Name	Description
OTHER	Cryotherapy	In the cryotherapy group, the pulp chamber was irrigated with 5 mL of sterile saline solution pre-cooled to 2.5°C during full pulpotomy.
DRUG	Dexametasone	In the dexamethasone group, the pulp chamber was irrigated with 2 mL of dexamethasone sodium phosphate solution (4 mg/mL) during full pulpotomy.

Timeline

• Start date: 2024-12-18
• Primary completion: 2025-05-05
• Completion: 2025-06-16
• First posted: 2025-11-18
• Last updated: 2025-11-24

Locations

1 site across 1 country: Turkey (Türkiye)