NCT06597487

The Effect of Prognostic Factors on the Success of Full Pulpotomy in Permanent Mature Molars With Irreversible Pulpitis

Influence of Wolters Classification of Pulpitis and the Radiographic Caries Depth Detected Using Artificial Intelligence on the Success of Full Pulpotomy in Permanent Mature Molars With Irreversible Pulpitis: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: Misr International University · Academic / Other
• Sex: All
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate the effect of prognostic factors, such as the degree of pulpal inflammation and the radiographic caries depth, on the success of full pulpotomy in mature permanent molars with irreversible pulpitis.

Detailed description

* Patients with mature permanent molars diagnosed with irreversible pulpitis will be enrolled in the study. * The pre-operative pulpal status will be assessed using the American Association of Endodontists (AAE) classification and Wolters classification. * Pre-operative radiographs will be taken, and radiographic caries depth will be assessed. * An Artificial Intelligence software will process the pre-operative X-rays to assess the presence of carious pulp exposure. The diagnostic accuracy of the software will be evaluated by comparing its readings with clinical findings of pulp exposure after caries removal. * The patients will be randomized to receive either full pulpotomy or conventional root canal treatment. * The patients will be followed up for 1, 3 and 6 months to assess clinical and radiographic success.

Conditions

• Pulpitis - Irreversible

Interventions

Type	Name	Description
PROCEDURE	Full pulpotomy	The patients will receive full pulpotomy as follows: -Under rubber dam isolation, the operator will perform caries removal, complete the access cavity preparation, achieve hemostasis from all canals, and apply the bioceramic material. The operator will seal the cavity with glass ionomer restoration.
PROCEDURE	Conventional root canal treatment	The patients will receive conventional root canal treatment, which is the gold standard treatment protocol in cases with irreversible pulpitis.

Timeline

• Start date: 2024-10-15
• Primary completion: 2025-07-01
• Completion: 2025-07-01
• First posted: 2024-09-19
• Last updated: 2025-07-25

Locations

1 site across 1 country: Egypt