NCT04697537

Ultrasound-guided Regional Anesthesia vs Local Infiltration Anesthesia With Dexmedetomidine and Ropivacaine

Dexmedetomidine as Adjunct Medication to Local Infiltration Anesthesia (LIA) vs Ultrasound-Guided Regional Anesthesia (USRA) in Regard to Patients' Need for Opioids, Wellbeing, Satisfaction, and Knee Functionality in Knee-endoprosthetics

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Evaluation of the Impact of dexmedetomidine as an adjunct for local infiltrations analgesia and ultrasound-based regional anaesthesia as pain medication in regard to patients' opioid need the first 48 hours after the total knee replacement operation.

Detailed description

Evaluation of the Impact of dexmedetomidine as an adjunct for local infiltrations analgesia and ultrasound-based regional anaesthesia as pain medication in regard to patients' opioid need the first 48 hours after the total knee replacement operation. Secondary objectives are: Pain assesment, Pain medication necessary, functionality of the prothesis, satisfaction, wellbeing, postoperative discomforts, complications (delirium, allergic reactions, cardiopulmonary decompensation), procedure specific time.

Conditions

• Pain, Postoperative
• Anesthesia, Local
• Gonarthrosis

Interventions

Type	Name	Description
DRUG	Ultrasound guided regional anesthesia	Applied perineurally preoperatively ultrasound guided regional anesthesia
DRUG	Local infiltration analgesia	Applied in the wound intraoperatively from the orthopedics

Timeline

• Start date: 2021-02-01
• Primary completion: 2021-04-09
• Completion: 2021-04-09
• First posted: 2021-01-06
• Last updated: 2021-04-14

Locations

1 site across 1 country: Austria