| Not Yet Recruiting | Hypoxia and Heart Rate Variability NCT05606406 | University of Miami | N/A |
| Not Yet Recruiting | Hypoxia and Hemodilution Testing in Healthy Adult Volunteers NCT07503171 | Nihon Kohden | — |
| Recruiting | Effect of Acute Hypoxia on RIght VEntRicular Function in Healthy Adults. NCT07431567 | Mona Lichtblau | N/A |
| Not Yet Recruiting | Effect of Acute Hypoxia on RIght VEntRicular Function in HAPE. NCT07431554 | Mona Lichtblau | N/A |
| Not Yet Recruiting | Effect of Acute Hypoxia on RIght VEntRicular Function in Asthma. NCT07431580 | Mona Lichtblau | N/A |
| Active Not Recruiting | Adaptation of Lung Transplant Recipients at Extreme Altitude NCT07479511 | Medical University of Vienna | — |
| Recruiting | Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia NCT07287293 | Mahidol University | N/A |
| Not Yet Recruiting | Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period NCT07231887 | Assiut University | N/A |
| Recruiting | The Efficacy and Safety of the Supraglottic Oxygenation Via Nasotracheal Intubation for Deep Sedation Fiberopt NCT07389083 | First Affiliated Hospital of Zhejiang University | N/A |
| Recruiting | High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea P NCT07307560 | Zhejiang University | N/A |
| Active Not Recruiting | Pulse Oximeter Accuracy During Stable Hypoxia Plateaus NCT07408388 | Nihon Kohden | — |
| Not Yet Recruiting | HVNI vs NIPPV in Type 2 Respiratory Failure NCT07065656 | National University Hospital, Singapore | N/A |
| Recruiting | The Efficacy of Remimazolam on Incidence of Hypoxia During Sedated Transvaginal Oocyte Retrieval: A Multicente NCT07335536 | Diansan Su | N/A |
| Withdrawn | Optical Brain Pulse Monitor: Validation Of Cerebral Oximetry Monitoring (OBPM:VOCOM) Study. NCT06657820 | Elliot Teo | N/A |
| Completed | Positive-Pressure vs Suction Extubation in Cesarean Patients NCT07251686 | Medipol University | N/A |
| Recruiting | Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude NCT07216755 | Embry-Riddle Aeronautical University | N/A |
| Completed | Integrated Pulmonary Index Monitoring on the Incidence of Hypoxemia in Elderly Patients With Painless Colonosc NCT06987630 | The First People's Hospital of Lianyungang | N/A |
| Completed | Pulse Oximeter Validation Study for the Perin Health Patch NCT07027150 | Perin Health Devices | — |
| Recruiting | Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Pati NCT06966934 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Completed | Running Title: Correlation Between Pulse Oximeter (SpO2) and ABG (SaO2) NCT07166718 | Tribhuvan University Teaching Hospital, Institute Of Medicine. | — |
| Active Not Recruiting | Graded Exercise Hypoxia Testing NCT06901284 | Mayo Clinic | — |
| Recruiting | COMBO Endoscopy Oropharyngeal Airway Reduces Hypoxia During Sedated Gastrointestinal Endoscopy in Obese Patien NCT06796764 | Zhejiang University | N/A |
| Recruiting | Safeguarding the Brain of Our Smallest Children-IIIv (SafeBoosC-IIIv) NCT05907317 | Copenhagen Trial Unit, Center for Clinical Intervention Research | Phase 3 |
| Completed | To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Satura NCT07097441 | Ziauddin University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Impact of Iron Supplementation on Right Ventricular Function and Exercise Performance in Hypoxia NCT05349630 | University of Colorado, Denver | EARLY_Phase 1 |
| Completed | Accuracy Of The Owlet OSS 3.0 During Standardized Stable Hypoxia Plateaus NCT06850610 | Owlet Baby Care, Inc. | N/A |
| Recruiting | Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With D NCT06846034 | Poitiers University Hospital | N/A |
| Completed | COMBO Endoscopy Oropharyngeal Airway in Sedated Gastrointestinal Endoscopy for Obese Patients NCT06804876 | Zhejiang University | Phase 2 |
| Completed | Combination COMBO Endoscopy Oropharyngeal Airway With High-Flow Nasal Cannula Oxygenation in Sedated Gastroint NCT06812403 | Zhejiang University | Phase 2 |
| Not Yet Recruiting | Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose- NCT06147232 | Steno Diabetes Center Copenhagen | Phase 2 |
| Recruiting | The Effects of Endotracheal Suctioning on Pain and Serum Markers NCT06692400 | Loma Linda University | N/A |
| Recruiting | Effect of Percutaneous Electrical Acupoint Stimulation on the Improvement of Incidence of Adverse Respiratory NCT06772961 | Nanjing First Hospital, Nanjing Medical University | N/A |
| Recruiting | Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients NCT06702813 | Shanghai Zhongshan Hospital | N/A |
| Completed | OM2 Low Saturation Verification NCT06661889 | Medtronic - MITG | — |
| Recruiting | Hypoxia, Appetite, and Energy Intake in Young Female Adults NCT06912230 | University of Ottawa | N/A |
| Recruiting | Outpatient Pediatric Pulse Oximeters in Africa NCT05914324 | Johns Hopkins University | N/A |
| Active Not Recruiting | Efficacy of High-flow Nasal Oxygen in Preventing Hypoxia During Gastrointestinal Endoscopy: a Retrospective Co NCT06710613 | Fengli Liu | — |
| Recruiting | High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Sedative Gastroscopy NCT06585306 | XiaoLiang Wang | N/A |
| Recruiting | The Effects of Ketone Ester Supplementation During a 5 Week Live High, Train Low Altitude Training Camp NCT06596083 | KU Leuven | N/A |
| Recruiting | Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Pat NCT06501118 | University of Colorado, Denver | N/A |
| Completed | The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spin NCT06566690 | Kocaeli University | — |
| Recruiting | End-Tidal Oxygen for Intubation in the Emergency Department NCT06578468 | Sydney Local Health District | N/A |
| Recruiting | Comparison of High Flow Nasal Oxygen and Nasal Cannula in Burn Patients Under Sedation NCT06756906 | Ankara City Hospital Bilkent | — |
| Completed | The Effect of Butanediol Ingestion on Skeletal Muscle Angiogenesis in Hypoxia NCT06472427 | KU Leuven | N/A |
| Withdrawn | Comparison of the Oxymask and Oxy2mask on Supplemental Oxygen Delivery NCT06433934 | Northwestern Medicine | N/A |
| Recruiting | Novel Hypoxia Imaging for Head and Neck Cancer: Imaging Phenotype for Personalized Treatment NCT06108089 | University of Utah | — |
| Recruiting | Accuracy of the EvieMED Ring Pulse Oximeter in Profound Hypoxia NCT06459206 | Movano Health | — |
| Recruiting | Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia NCT06417177 | University of Missouri-Columbia | EARLY_Phase 1 |
| Recruiting | Effects of Normobaric Hypoxia Exercise Program on Bone Turnover Markers and Metabolism in Premenopausal Women NCT06226168 | University School of Physical Education, Krakow, Poland | N/A |
| Completed | Characterizing Hypoxic Apnea Intra-individual Repeatability NCT06399575 | University of Alberta | N/A |
| Recruiting | Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer NCT06353061 | Peking Union Medical College Hospital | Phase 2 |
| Completed | Effects of Hypoxia on Cognitive Performance NCT06318312 | University of Castilla-La Mancha | N/A |
| Completed | OM2 Motion Verification Study NCT06415786 | Medtronic - MITG | — |
| Completed | Hypoxemia in the First 24 Hours After Trauma - an Observational Study NCT06256692 | Rigshospitalet, Denmark | — |
| Completed | OM2 Abbreviated Sensor Verification NCT06415799 | Medtronic - MITG | — |
| Completed | Evaluating Sleep Quality With Emerging Technologies NCT06900530 | Case Western Reserve University | — |
| Recruiting | Effect of Hypoxia on FMISO PET to Response to Lu-177 PSMA Treatment NCT06433063 | Cigdem Soydal | N/A |
| Unknown | Evaluation of the Response to Hypoxia at Rest and During Exercise in a Healthy Subject After a Cryostimulation NCT06174480 | Poitiers University Hospital | N/A |
| Completed | Accuracy of Evie Ring Pulse Oximeter in Profound Hypoxia NCT06101654 | Movano Health | — |
| Recruiting | The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reprodu NCT06187896 | RenJi Hospital | N/A |
| Recruiting | The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure NCT06081647 | RenJi Hospital | N/A |
| Active Not Recruiting | Pharmacologic Induction of Tolerance for Hypoxia & Hypothermia NCT06129825 | University of Maryland, Baltimore | — |
| Unknown | Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function NCT06158256 | Centro Universitario La Salle | Phase 3 |
| Unknown | Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function NCT06150677 | Centro Universitario La Salle | Phase 3 |
| Unknown | Effects of Walking Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function NCT06158295 | Centro Universitario La Salle | Phase 3 |
| Unknown | Effects of Walking Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function NCT06158282 | Centro Universitario La Salle | Phase 3 |
| Completed | Controlled Desaturation Study for TipTraQ SpO2 Performance Validation NCT06634693 | PranaQ Pte. Ltd. | — |
| Recruiting | High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill NCT05883137 | Region Stockholm | — |
| Unknown | Intermittent Exogenous Ketosis (IEK) at High Altitude NCT06097754 | Jozef Stefan Institute | N/A |
| Unknown | Hypoxia-induced Autophagy in the Pathogenesis of MAP NCT05817448 | Assiut University | — |
| Completed | Ketone Esters for Optimization of Operator Performance in Hypoxia NCT07065864 | Florida Institute for Human and Machine Cognition | N/A |
| Not Yet Recruiting | The Effects of Remimazolam on the Incidence of Hypoxia During Sedated Hysteroscopy for Assisted Reproduction i NCT06004843 | RenJi Hospital | N/A |
| Completed | Hypoxia Adaptation Promotes Cerebral Functional Connectivity With Neuromuscular Efficiency Decrement NCT07018817 | Peking Union Medical College | — |
| Completed | Comparison of Hypoxia Between HFNC and SNC in Patient Undergoing UGI Endoscopic Procedures in Deep Sedation NCT06482879 | National Academy of Medical Sciences, Nepal | — |
| Completed | SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor With Motion Conditions NCT06149416 | Stryker Sustainability Solutions | N/A |
| Completed | Analysis of HIF-1α, MDA, and GPX4 in Peri-Implant Crevicular Fluid NCT06863116 | Ege University | — |
| Completed | Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia NCT05256069 | University of Missouri-Columbia | EARLY_Phase 1 |
| Recruiting | HFNC Compared With Facial Mask in Patients With Chest Trauma Patients NCT05828030 | National Taiwan University Hospital | N/A |
| Completed | The Effects of Different Prone Positioning Angles on Cardiopulmonary Function in Children After Congenital Hea NCT07323979 | Guangdong Provincial People's Hospital | N/A |
| Unknown | Diastolic Deceleration Area in Late-onset FGR NCT05837195 | Orthogyn Medical Center, Bulgaria | — |
| Completed | Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO19) NCT05807477 | Nihon Kohden | — |
| Recruiting | Going to Altitude With Anxious-depressive Symptoms NCT05323864 | Universitaet Innsbruck | N/A |
| Completed | Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO18) NCT05807464 | Nihon Kohden | — |
| Completed | Regulation of Satellite Cells and Myogenesis in Response to Eccentric Resistance Exercise in Hypoxia NCT07341165 | Université Catholique de Louvain | N/A |
| Completed | High Flow Nasal Oxygen Versus Standard Nasal Oxygen in Endoscopic Retrograde Cholangiopancreatography Under Se NCT06689033 | Ankara City Hospital Bilkent | — |
| Completed | Comparison of SpO2 Measurement Accuracy of Different Types of Smartwatches NCT05789563 | Czech Technical University in Prague | N/A |
| Recruiting | Added Diagnostic Value of Point of Care Ultrasound in Acute Dyspnea NCT05782478 | Region Skane | — |
| Completed | Caffeine and Hypoxia During Exercise in Males and Females NCT05764018 | Jozef Stefan Institute | N/A |
| Unknown | Prospective Study to Validate the Clinical Accuracy of the Norbert Device to Measure Oxygen Saturation NCT05685654 | Norbert Health | — |
| Completed | In Vivo Pulse Oximeter Validation Study NCT05873335 | Gabi SmartCare | N/A |
| Unknown | Oxygen Partial Pressure After Breast Cancer Surgery NCT05737446 | Umeå University | — |
| Completed | Effect of Ketone Ester Supplementation on Sleep and Recovery in Hypoxia NCT06060093 | KU Leuven | N/A |
| Unknown | Evaluation of Medical Device for Airway Patency During Sedation (SW01-2022) NCT05708651 | Stairway Medical AB | N/A |
| Unknown | SpO2 Difference Between Fingers of the Hand During Sequential Desaturation and Step Resaturation NCT05681637 | Czech Technical University in Prague | N/A |
| Unknown | Accuracy of Pulse Oximeters During Profound Hypoxia NCT05790616 | Philips Clinical & Medical Affairs Global | N/A |
| Completed | Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO17) NCT05745662 | Nihon Kohden | — |
| Completed | Accuracy of Pulse Oximeters With Profound Hypoxia At Rest (NIHO16) NCT05745675 | Nihon Kohden | — |
| Withdrawn | Oxygen Insufflation in Microlaryngoscopies NCT04979533 | University of Alabama at Birmingham | N/A |
| Unknown | SpO2 Comparison Between Commercial Smartwatch and Medical-grade Pulse Oximeter During Hypoxia NCT05657288 | Czech Technical University in Prague | N/A |
| Completed | Effect of Ketone Ester Supplementation on Hypoxic Tolerance NCT05588427 | KU Leuven | N/A |
| Completed | Repeated Sprint Training in Normobaric Hypoxia NCT05967767 | Ankara University | N/A |
| Unknown | Effect of Acute Sleep Restriction on Responses to Hypoxia NCT05563688 | Direction Centrale du Service de Santé des Armées | — |
| Completed | Accuracy of Pulse Oximeters in Profound Hypoxia NCT05920278 | Movano Health | — |
| Terminated | The Effect of Continued Mechanical Ventilation on the Occurrence of Myocardial Ischemia NCT05417217 | Jessa Hospital | N/A |
| Unknown | SJOV vs. HFNO for Hypoxia During Procedural Sedation at High Altitudes NCT05474287 | Peking University People's Hospital | N/A |
| Completed | We Compared the Covid-19 Acute Respiratory Distress Syndrome (ARDS) Patients Who Applied Prone Positioning for NCT06530095 | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | — |
| Completed | N600X Low Saturation Accuracy Validation NCT05532670 | Medtronic - MITG | — |
| Completed | Nasal Mask Kit in Gastrointestinal Endoscopy NCT05405530 | RenJi Hospital | N/A |
| Completed | Efficacy of 20% Human Albumin in Reducing Pleural Effusion After Cardiopulmonary Bypass NCT06681415 | Pauls Stradins Clinical University Hospital | Phase 4 |
| Completed | Accuracy of BabySat V3 With Profound Hypoxia and Motion NCT05581394 | Owlet Baby Care, Inc. | — |
| Completed | The Effect of Hypercapnia on Physiological Parameters During Short-term Breathing NCT05441007 | Czech Technical University in Prague | N/A |
| Completed | Nasotracheal Intubation With VL vs DL in Infants Trial NCT05433155 | Children's Hospital of Philadelphia | N/A |
| Completed | Accuracy of CardioWatch 287-2 During Profound Hypoxia NCT05542732 | Corsano Health B.V. | N/A |
| Unknown | High Flow Nasal Oxygen Therapy Undergoing Colonoscopy NCT05396274 | Turkish Society of Anesthesiology and Reanimation | N/A |
| Completed | NICU Oxygen Control Study NCT04269161 | University of Missouri-Columbia | N/A |
| Unknown | A Potential Role for Oxygen in the Development of Mental Fatigue and the Subsequent Decline in Cognitive Perfo NCT05100667 | Vrije Universiteit Brussel | N/A |
| Completed | RDS MultiSense® SpO2 Validation Study NCT05359328 | Rhythm Diagnostic Systems | N/A |
| Unknown | Supraglottic Jet Oxygenation and Ventilation for Gastrointestinal Endoscopy at High-altitude NCT05304923 | Peking University People's Hospital | N/A |
| Unknown | Effects of Hypoxic Repeated Sprint Training on Performance in Normoxia in Male and Female Athletes NCT05439239 | Université Catholique de Louvain | N/A |
| Recruiting | FMISO-based Adaptive Radiotherapy for Head and Neck Cancer NCT05348486 | University Hospital Olomouc | N/A |
| Unknown | Diastolic Deceleration Area in Early-onset FGR NCT05820464 | Orthogyn Medical Center, Bulgaria | — |
| Completed | Impact of Hypoxia on Resting and Exertional Right Ventricular Performance NCT05272514 | University of Colorado, Denver | — |
| Recruiting | Intravenous Iron Effects on Performance at High Altitude NCT06686693 | United States Army Research Institute of Environmental Medicine | Phase 4 |
| Completed | Efficiency and Safety of Nasal Positive Airway Pressure Systems During Endoscopy NCT05972304 | University of Ulm | N/A |
| Completed | The 90% Effective Flow of High Flow Nasal Oxygenation (HFNO) During Sedated Bronchoscopy NCT05298319 | Zhejiang Cancer Hospital | N/A |
| Active Not Recruiting | Determination of SpO2 and PR Accuracy Specifications at Rest (71Ag_Vital-0031) NCT05297500 | Nihon Kohden | — |
| Unknown | Postoperative Hypoxia and Body Position NCT05246605 | Umeå University | N/A |
| Completed | RDS MultiSense® SpO2 Calibration NCT05466942 | Rhythm Diagnostic Systems | N/A |
| Completed | SpO2 Accuracy of Noninvasive Disposable Pulse Oximeter Sensor With Motion Conditions NCT05264116 | Stryker Sustainability Solutions | N/A |
| Unknown | Clinical Impact of Automated Oxygen Administration on Confirmed or Suspected COVID-19 in the Emergency Departm NCT05235386 | Laval University | — |
| Completed | Effect of FFP2 Masks on Peripheral Oxygen Saturation and Pulse Rate During the COVID-19 Pandemic NCT05188651 | Catholic University of the Sacred Heart | — |
| Completed | The Effect of Mechanical Ventilation on the Occurrence of Myocardial Ischemia: a Pilot Study NCT05109715 | Jessa Hospital | N/A |
| Completed | SpO2 Accuracy of Noninvasive Disposable Pulse Oximeter Sensor NCT05245526 | Stryker Sustainability Solutions | N/A |
| Completed | HFNC and Hypoxia/Desaturation During Radiofrequency Ablation Under Moderate Sedation: A Randomized Clinical Tr NCT05212064 | Zhejiang Cancer Hospital | N/A |
| Withdrawn | An Alternative Way To Deliver Oxygen To People NCT04870801 | Christopher Bell | EARLY_Phase 1 |
| Completed | Comparison of Different Walk and Performance Test in Detecting Silent Hypoxia NCT05709262 | Kutahya Health Sciences University | — |
| Recruiting | Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior NCT05767385 | University of Utah | Phase 2 / Phase 3 |
| Completed | Carotid Body Function in Type 2 Diabetes Mellitus NCT05237076 | Leiden University Medical Center | N/A |
| Recruiting | Pulse Oximeter Accuracy in Healthy Humans During Hypoxia NCT06142019 | University of California, San Francisco | — |
| Completed | SpO2 Accuracy of Noninvasive Pulse Oximeter Sensor NCT05141500 | Stryker Sustainability Solutions | N/A |
| Terminated | A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma NCT05119335 | NiKang Therapeutics, Inc. | Phase 1 / Phase 2 |
| Completed | Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants NCT05189158 | Centre Hospitalier Universitaire Saint Pierre | N/A |
| Unknown | Effect of Hypoxic Conditioning on Cerebrovascular Health in the Elderly NCT05048680 | University Hospital, Grenoble | N/A |
| Unknown | Hypoxia-driven Prostate Cancer Genomics (HYPROGEN) NCT05702619 | The Christie NHS Foundation Trust | — |
| Completed | Isolated and Combined Effect of a Low Carbohydrate Diet and Exercise in Hypoxia in Patients With Type 2 Diabet NCT05094505 | Universidade do Porto | N/A |
| Withdrawn | Comparing Inpatient COVID-19 Outcomes in 2 Different PT Dosing Groups NCT04844307 | Montefiore Medical Center | N/A |
| Completed | Evaluation of RDS MultiSense® in Desaturation Analysis in Healthy Volunteers NCT05044585 | IHU Strasbourg | N/A |
| Completed | Capnographic Monitoring in Gastrointestinal Endoscopy for Elderly Patients NCT05030870 | RenJi Hospital | N/A |
| Completed | CPAP Or Nasal Cannula Oxygen for Preterm Infants: A Randomized Controlled Trial NCT04792099 | University of Alabama at Birmingham | N/A |
| Completed | Tools for the Integrated Management of Childhood Illness: Cross-country Quasi-experimental Pre-post Study in K NCT05065320 | Swiss Tropical & Public Health Institute | — |
| Unknown | Nitric Oxide During Cardiopulmonary Bypass in Adult Surgery NCT04807413 | Rabin Medical Center | Phase 3 |
| Completed | Motor Plasticity, Intermittent Hypoxia and Sleep Apnea NCT04017767 | University of Miami | N/A |
| Completed | Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Deci NCT04910750 | Swiss Tropical & Public Health Institute | N/A |
| Completed | Accuracy of Pulse Oximeter With Profound Hypoxia NCT05693168 | Sibel Health Inc. | N/A |
| Unknown | Prevention of Perioperative Pulmonary Complications by Lung Recruitment During Laparoscopic Surgery NCT04728945 | Osaka University | N/A |
| Completed | Preoxygenation With High-flow Nasal Oxygen in Adult Trauma Patients During Rapid Sequence Induction Anaesthesi NCT04926337 | Karolinska University Hospital | — |
| Unknown | High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity NCT04500392 | RenJi Hospital | N/A |
| Completed | Hypoxia Intolerance in Preterm Individuals NCT04739904 | Jozef Stefan Institute | — |
| Terminated | AirFLO2 Treatment for Hypoxia and/or Tachypnea in Patients With COVID-19 NCT04649775 | Duke University | N/A |
| Completed | SpO2 Accuracy Low Saturation Validation of the OxySoftN Sensor NCT04811963 | Medtronic - MITG | — |
| Completed | Accuracy of Pulse Oximeters With Profound Hypoxia During Motion NCT04814342 | Nihon Kohden | — |
| Completed | Accuracy of Pulse Oximeters With Profound Hypoxia at Rest NCT04814823 | Nihon Kohden | — |
| Unknown | Efficacy and Safety of Remimazolam Tosylate for Sedation in Gastroscopy NCT04727034 | RenJi Hospital | N/A |
| Completed | Evaluation of SpO2 Measurement Using a Smartwatch NCT04780724 | Czech Technical University in Prague | N/A |
| Completed | Relationship Between STOP BANG Score and Airway Management NCT05640856 | Zonguldak Bulent Ecevit University | — |
| Completed | Different Preoxygenation Methods In Cesarean Section NCT05395975 | Zonguldak Bulent Ecevit University | — |
| Withdrawn | Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation NCT03066115 | University of Wisconsin, Madison | Phase 1 |
| Withdrawn | Mask Hypoxia in Subjects Using Masks to Prevent Infection Spread NCT04670484 | University of New Mexico | N/A |
| Completed | Servo Controlled Oxygen Targeting (SCO2T) Study: Masimo vs. Nellcor NCT04866342 | University of Edinburgh | N/A |
| Recruiting | Nocturnal Hypoxia in Geriatric Patients After Hip Fracture NCT04007432 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Variability of SpO2 Measurements Depending on the Choice of Finger for Sensor Placement NCT04771663 | Czech Technical University in Prague | N/A |
| Completed | Effect of Oral Ketone and Sodium Bicarbonate Administration During Endurance Exercise in Hypoxia NCT04579770 | Jozef Stefan Institute | N/A |
| Unknown | Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment NCT04918914 | Hunt Regional Medical Center | EARLY_Phase 1 |
| Recruiting | Structural Modification In Supraglottic Airway Device NCT04498598 | The Cleveland Clinic | N/A |
| Completed | The VISION-Acute Study NCT04589923 | Xim Limited | — |
| Completed | Higher vs. Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia NCT04509973 | Scandinavian Critical Care Trials Group | Phase 3 |
| Completed | Belun SpO2 Accuracy Comparison to Arterial Blood CO-Oximetry NCT04873947 | Belun Technology Company Limited | — |
| Completed | SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study NCT04559763 | Medtronic - MITG | — |
| Completed | The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia NCT04231773 | University of Alberta | Phase 1 / Phase 2 |
| Terminated | SCO2T (Servo vs. Servo) NCT04546568 | University of Edinburgh | N/A |
| Completed | Studies to Determine Whether Oxygen Sensing is Impaired in Severe Acute Respiratory Syndrome Coronavirus 2 (SA NCT04954157 | University of Chicago | N/A |
| Completed | Nebulised Dornase Alfa for Treatment of COVID-19 (Coronavirus Disease 2019) NCT04359654 | University College, London | Phase 2 |
| Completed | Hydrocortisone for COVID-19 and Severe Hypoxia NCT04348305 | Scandinavian Critical Care Trials Group | Phase 3 |
| Completed | Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation NCT04357782 | Hunter Holmes Mcguire Veteran Affairs Medical Center | Phase 1 / Phase 2 |
| Completed | Accuracy of Owlet Smart Sock Sensor 3rd Generation With Profound Hypoxia NCT04446247 | Owlet Baby Care, Inc. | — |
| Completed | Use of Oxygen Hoods in Patients Failing on Conventional High-flow Oxygen Delivery Systems, Effects on Oxygenat NCT04407260 | Northwell Health | — |
| Unknown | Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema NCT04288219 | Massachusetts General Hospital | N/A |
| Completed | Acute Effects of SGLT2 Inhibition on Renal Oxygenation and Autonomic Function in Type 1 Diabetes NCT04193566 | Steno Diabetes Center Copenhagen | Phase 4 |
| Completed | Measuring Oxygenation of Newborn Infants in Targeted Oxygen Ranges NCT03360292 | University of Edinburgh | N/A |
| Completed | Servo Controlled Oxygen Targeting Study NCT04177992 | University of Edinburgh | N/A |
| Completed | Autonomic Activity During Nap Under Hypoxia NCT04146857 | Charite University, Berlin, Germany | N/A |
| Completed | Automated Oxygen Control by O2matic to Patients Admitted With Acute Hypoxemia NCT04079465 | Hvidovre University Hospital | N/A |
| Unknown | Intravascular Volumes in Hypoxia During Antarctic Confinement NCT04106401 | Ecole Nationale des Sports de Montagne | N/A |
| Completed | Is Reduced Hypoxia Through a Robot Intervention, Associated With Sensory and Emotional Descriptions of Dyspnea NCT04375917 | Copenhagen University Hospital, Hvidovre | N/A |
| Completed | Automated Oxygen Administration -Rethinking Interventions Alleviating Dyspnea in Patients With COPD NCT04370990 | Copenhagen University Hospital, Hvidovre | N/A |
| Completed | Triple H ODC Trial NCT04041531 | Medical University Innsbruck | N/A |
| Terminated | Effectiveness of Chest Compressions Under Mild Hypoxia NCT04072484 | University of Chicago | N/A |
| Unknown | Influence of HFNO on Spontaneous Ventilation in Patients of Different ASA Risk During Analgo-sedation for Vitr NCT04055077 | University of Split, School of Medicine | N/A |
| Completed | Improving Safety of Diagnosis and Therapy in the Inpatient Setting NCT04393909 | Brigham and Women's Hospital | N/A |
| Completed | The Psychophysiological Effect of Simulated and Terrestrial Altitude NCT04075565 | University of Applied Sciences and Arts of Southern Switzerland | N/A |
| Completed | Dark Chocolate and Exercise Performance in Hypoxia NCT03945916 | University of Saskatchewan | N/A |
| Unknown | Non-Contact Respiratory Rate Monitoring NCT04005911 | University of Virginia | — |
| Completed | Trans Alveolar Pressure Measurement as an Index for Lung Recruitment. NCT04168151 | University of Alexandria | N/A |
| Suspended | Evaluation of the Effect of Sevoflurane and Propofol Hypotensive Anesthesia on Blood Antioxidant Levels and HI NCT04246567 | Bezmialem Vakif University | N/A |
| Completed | BiOSENCY BORA Band SpO2 Validation Study NCT03918018 | Biosency | N/A |
| Terminated | Comparison of Oxygen Controllers in Preterm InfanTs NCT03877198 | Leiden University Medical Center | N/A |
| Completed | Oxygen Reserve Index for Kids NCT03845192 | Johannes Gutenberg University Mainz | N/A |
| Completed | Intermittent Hypoxia Therapy in Cardiac Rehabilitation NCT04034082 | Istituti Clinici Scientifici Maugeri SpA | N/A |
| Completed | Exercise in Hypoxia and Nitrate Supplementation in Athletes: is the Whole Greater Than the Sum of Its Parts? NCT06727656 | University of Trás-os-Montes and Alto Douro | N/A |
| Completed | Polso SpO2 Accuracy Validation Study NCT03735329 | ChroniSense Medical Ltd. | N/A |
| Completed | Effect of PEEP on Lung Regional Ventilation and Perfusion NCT04081155 | Yun Long | — |
| Completed | Pulse Oximeter and Respiratory Rate Test NCT03797300 | Spry Health | N/A |
| Completed | Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD NCT03661086 | Hvidovre University Hospital | N/A |
| Unknown | Nasopharyngeal Airway Facilitate Transnasal Humidified Rapid Insufflation Ventilatory Exchange NCT03741998 | RenJi Hospital | N/A |
| Terminated | Computer-assisted Oxygen Therapy Weaning in Critically Ill Children NCT03550469 | Stanford University | N/A |
| Completed | Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia NCT03695315 | University of California, San Francisco | — |
| Unknown | Can High-flow Nasal Oxygenation Improve Oxygen Saturation During Analgo-sedation in Obese Adults? NCT03687424 | University of Split, School of Medicine | N/A |
| Unknown | The Effect of High-flow Nasal Oxygenation to the Saturation During Analgo-sedation in Different ASA Risk Class NCT03687385 | Anita Vukovic | N/A |
| Completed | Acetazolamide and Exercise Performance at Altitude NCT03525561 | United States Army Research Institute of Environmental Medicine | EARLY_Phase 1 |
| Unknown | Ketone Esters for Optimization of Cognitive Performance in Hypoxia NCT03659825 | HVMN Inc | N/A |
| Completed | The Nitrite and Coronary Flow Study NCT04354051 | University of East Anglia | Phase 1 / Phase 2 |
| Completed | Double Trunk Mask and Standard Nasal Cannula During Acute Hypoxia NCT03457363 | Laboratory of Movement, Condorcet, Tournai, Belgium | N/A |
| Unknown | High Flow Therapy in ICUs Across Ibero America NCT03364946 | Fundación Santa Fe de Bogota | — |
| Completed | Automated Oxygen Delivery by O2matic to Patients Admitted With an Exacerbation in COPD NCT03464695 | Hvidovre University Hospital | N/A |
| Terminated | Exercise for Improving Prostate Oxygenation in Prostate Tumors (Exipox) NCT03365076 | University Hospital of North Norway | N/A |
| Completed | Pre-oxygenation With High-flow Nasal Cannula in Adults During Rapid Sequence Induction Anesthesia NCT03516175 | Karolinska University Hospital | N/A |
| Completed | Positive Pressure at Induction of Anesthesia in Children NCT03432390 | Instituto Materno Infantil Prof. Fernando Figueira | N/A |
| Unknown | Investigation of Hemoglobin Oxygenation With Third Harmonic Generation Microscopy NCT03619356 | National Taiwan University Hospital | — |
| Completed | The Relationship Between Postoperative Oxygenation and STOP-BANG Questionnaire and 4-V Tool NCT03838705 | Umraniye Education and Research Hospital | N/A |
| Active Not Recruiting | Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy NCT03168815 | Mount Sinai Hospital, Canada | N/A |
| Completed | Myocardial Injury and Intraoperative Tissue Oximetry in Patients Undergoing Spine Surgery NCT03518372 | University of California, San Francisco | — |
| Completed | RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia NCT03369093 | International Centre for Diarrhoeal Disease Research, Bangladesh | N/A |
| Completed | AT1R Blockade and Periodic Breathing During Sleep in Hypoxia NCT03335904 | University of British Columbia | Phase 4 |
| Completed | SpO2 Accuracy Comparison of Smart Sock V. 2 SpO2 to Arterial Blood CO-Oximetry NCT03630016 | Owlet Baby Care, Inc. | N/A |
| Completed | High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Gastroscopy Sedated by Propofol NCT03332433 | RenJi Hospital | N/A |
| Completed | SpO2 Hypoxia Accuracy Validation Study NCT03348189 | Nonin Medical, Inc | — |
| Completed | Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal NCT03369197 | Johns Hopkins University | N/A |
| Completed | Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients NCT03221387 | Temple University | N/A |
| Completed | Pulse Oximeter Test NCT03569163 | Spry Health | — |
| Completed | Portable Oxygen Concentrator Signal Capture Study NCT03182036 | ResMed | N/A |
| Completed | Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy P NCT03529461 | Bristol Hospital | N/A |
| Completed | Aerobic Interval Training in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypoxemia NCT03092622 | Norwegian University of Science and Technology | N/A |
| Completed | Accuracy Validation of Belun Oxygen Saturation Pulse Oximeter FDA Submission Study NCT03439306 | Belun Technology Company Limited | — |
| Unknown | Overcoming Chemoresistance in Advanced Ovarian Cancer Via Targeting Hypoxia NCT04001023 | Turku University Hospital | N/A |
| Unknown | The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Il NCT03138200 | Szeged University | N/A |
| Completed | Conservative Versus Liberal Oxygenation Targets in Critically Ill Children NCT03040570 | Great Ormond Street Hospital for Children NHS Foundation Trust | N/A |
| Completed | Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation NCT03093662 | Brooke Army Medical Center | N/A |
| Completed | Evaluation of the ORTHO-LBNP System NCT03354234 | Military Institute of Aviation Medicine | N/A |
| Completed | Human Metabolic Dynamics at Rest and During Aerobic Exercise Under Normobaric Normoxic and Moderate Hypoxic Co NCT03121885 | Benjamin Gollasch | N/A |
| Completed | The Effect of Prolonged Inspiratory Time on Pulmonary Mechanics in Obese Patients NCT02961920 | Gachon University Gil Medical Center | N/A |
| Completed | Muscle Fatigue and Carbonic Anhydrase Inhibitors NCT02758470 | University of British Columbia | Phase 4 |
| Completed | Doxapram as an Additive to Propofol Sedation in Sedation for ERCP NCT02171910 | Helsinki University Central Hospital | Phase 4 |
| Completed | The Effect of ECMO on the Pharmacokinetics of the Drugs and Their Clinical Efficacy NCT03659513 | University of Pennsylvania | — |
| Unknown | DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy NCT02661152 | Danish Head and Neck Cancer Group | Phase 3 |
| Terminated | Evaluation of Accuracy and Precision of a New Arterial Blood Gas Analysis System Blood in Comparison With the NCT02801162 | Universitair Ziekenhuis Brussel | N/A |
| Completed | Oxygen Tension on Human Embryonic Development NCT03964805 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Hypoxia Blood Validation in Multiple Pulse Oximeters NCT00881829 | Clinimark, LLC | — |
| Completed | Oxitone Sp02 Hypoxia Test Versus Reference Pulse Oximetry NCT02870179 | Oxitone Medical Ltd. | — |
| Completed | Pulse Oximeter Motion Study NCT03156140 | University of California, San Francisco | N/A |
| Unknown | Cardio-respiratory Responses During Hypoxic Exercise in Individuals Born Prematurely NCT02780908 | Jozef Stefan Institute | N/A |
| Completed | Environmental or Nasal Cannula Oxygen for Preterm Infants Receiving Oxygen Therapy: a Randomized Cross-over Pi NCT02794662 | University of Alabama at Birmingham | N/A |
| Completed | Efficacy and Safety of Using Noninvasive Ventilation Associated With Recruitment Maneuver in Cardiac Surgery. NCT02913391 | Mieko Cláudia Miura | N/A |
| Unknown | Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy NCT01855347 | Brigham and Women's Hospital | — |
| Completed | The Effect of Chronic Nitrate Supplementation on Acute Mountain Sickness and Exercise Performance in Hypoxia NCT03101904 | Bangor University | N/A |
| Completed | Assessment of Preoxygenation Strategies in the Prehospital Environment NCT02694705 | Queen Mary University of London | N/A |
| Completed | Intelligent Oxygen Therapy During Activities of Daily Living NCT02683486 | Imperial College London | N/A |
| Unknown | Comparison of Two Pulse Oximeters in Delivery Room NCT02704585 | Shaare Zedek Medical Center | N/A |
| Unknown | Effects of Hypoxia and Inflammation on Citrulline Synthesis by Ornithine Transcarbamylase in Human Enterocytes NCT02820064 | University Hospital, Grenoble | N/A |
| Completed | Finger Pulse Oximeters in Hosptial Setting NCT06994663 | Barts & The London NHS Trust | — |
| Completed | Safe Limits in Saturation (SLIM-study) NCT02666937 | Amsterdam UMC, location VUmc | — |
| Completed | FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study NCT02612415 | Great Ormond Street Hospital for Children NHS Foundation Trust | Phase 2 / Phase 3 |
| Completed | The Evaluation of a Mobile Device to Measure Ataxia With High Altitude Exposure NCT02600078 | University of British Columbia | N/A |
| Completed | Endurance Performance at Altitude NCT03710369 | University of British Columbia | N/A |
| Unknown | Effect of Hypoxia on Cognitive Assessment and Cerebral Activity in Healthy Volunteers NCT02891343 | University Hospital, Lille | N/A |
| Completed | Studies on the Adaptive Responses to Hypoxia NCT02629406 | Karolinska University Hospital | — |
| Completed | Advancement of Modified Bubble CPAP NCT02208323 | University of Minnesota | Phase 2 |
| Completed | Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical Patients NCT05354648 | Federal Research Clinical Center of Federal Medical & Biological Agency, Russia | N/A |
| Completed | SpO2 Accuracy Validation of Pulse Oximetry Systems During Motion and Non-Motion Conditions NCT02475668 | Nonin Medical, Inc | — |
| Completed | Apneic Oxygenation During Airway Management in Pediatric Patients NCT02437864 | University of New Mexico | N/A |
| Completed | Reverse Trendelenburg Positioning and Its Effect on Outcomes: a Retrospective Study of Consecutive Patients NCT02984657 | C. Michael Dunham | — |
| Unknown | Effects of High Flow Nasal Cannula on Deadspace Reduction and Regional Distribution of Ventilation NCT02460653 | Boston Children's Hospital | N/A |
| Terminated | Effect of Short-term Simulated Altitude Exposure on Cardiopulmonary Functional Capacity NCT02523716 | University of Limerick | N/A |
| Unknown | WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal Endoscopy NCT02436018 | RenJi Hospital | N/A |
| Completed | qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia. NCT02466828 | Sunnybrook Health Sciences Centre | EARLY_Phase 1 |
| Completed | Prevalence of Sleep Apnea in Patients Undergoing Surgery for Colorectal Cancer NCT02323464 | Karl A Franklin | — |
| Withdrawn | Spirometric Detection of Esophageal Intubation NCT02052869 | University Medical Center Groningen | N/A |
| Completed | The Impact of Hypoxia on the Biochemical and Morphological Parameters of Blood in Rowers. NCT06264193 | Poznan University of Physical Education | N/A |
| Completed | Controlled Acute Hypoxia Study Comparing Pulse Oximetry to Arterial Blood Samples During Motion NCT02247765 | Medtronic - MITG | Phase 3 |
| Unknown | Non Contact Measurement of Vital Signs NCT02287220 | University of Virginia | — |
| Unknown | Oxygen Supplementation During Bronchoscopy: High Flow Versus Low Flow Oxygen NCT02253706 | Shaare Zedek Medical Center | N/A |
| Completed | Diaphragmatic Paralysis in Arthroscopic Shoulder Surgery NCT03192865 | Clinique Medipole Garonne | — |
| Completed | Non-invasive Intervention for Apnea of Prematurity NCT02641249 | University of California, Los Angeles | N/A |
| Completed | Regional Ventilation During High Flow Nasal Cannula and Conventional Nasal Cannula in Patients With Hypoxia NCT02943863 | Asan Medical Center | N/A |
| Unknown | Intrinsic Periodic Pattern of Breathing NCT02201875 | Association pour la Recherche en Physiologie de l'Environnement | — |
| Completed | Controlled Acute Hypoxia Study - Abbreviated Sensor Line NCT02216344 | Medtronic - MITG | — |
| Completed | Effect of Oxygen Supplementation During Exercise in Chronic Obstructive Pulmonary Disease Patients NCT02108925 | LHL Helse | N/A |
| Completed | Effect of Hypoxic Exposure on Blood Variables in Elite Wrestlers NCT06373562 | Poznan University of Physical Education | N/A |
| Completed | Use of Capnography in EGD and Colonoscopy With Moderate Sedation. NCT01994785 | The Cleveland Clinic | N/A |
| Completed | Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study NCT01997515 | Northwestern University | Phase 4 |
| Completed | Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α NCT01978158 | Radboud University Medical Center | Phase 1 / Phase 2 |