NCT04146857

Autonomic Activity During Nap Under Hypoxia

Effects of Normobaric Hypoxia on Autonomic Activity During a Nap in Healthy Adults (NAPOXIA)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Charite University, Berlin, Germany · Academic / Other
• Sex: All
• Age: 25 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Sleeping under hypoxic conditions can impair cognition and autonomic nervous activity. A short daytime nap can modify these changes. Here we propose a randomized, cross-over study to evaluate the heart rate variability during a 90 min nap in a normobaric hypoxic chamber. In addition, we will investigate sleep architecture, vigilance, attention and memory.

Conditions

• Hypoxia
• Sleep
• Healthy

Interventions

Type	Name	Description
OTHER	Normoxia	Nap in hypoxia chamber at 20.9% oxygen (36 m asl)
OTHER	Hypoxia 1	Nap in hypoxia chamber at 15.0% oxygen (simulates 2660 m asl)
OTHER	Hypoxia 2	Nap in hypoxia chamber at 12.8% oxygen (simulates 4000 m asl)

Timeline

• Start date: 2019-10-30
• Primary completion: 2020-12-30
• Completion: 2020-12-30
• First posted: 2019-10-31
• Last updated: 2022-07-11

Locations

1 site across 1 country: Germany