NCT06596083

The Effects of Ketone Ester Supplementation During a 5 Week Live High, Train Low Altitude Training Camp

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate the effects of post-exercise and pre-sleep exogenous ketosis via oral ketone ester supplementation during a 5 week simulated altitude training camp.

Detailed description

Altitude training camps, where you train at sea level but live at altitude, have become a popular way for athletes to prepare for upcoming races or events. The main aim of such training camps is to benefit from the adaptations following prolonged hypoxic exposure (increased EPO concentrations leading to an increase in oxygen carrying capacity in the blood). Recently, ketone bodies have been shown to cause similar adaptations. Therefore, this study aims to investigate whether the combination of exogenous ketosis and an altitude training camp is more beneficial compared to an altitude training camp on its own. Participants will follow a 5 week simulated altitude training camp where they spend 75 hours per week at altitude (2000-3000 meters), while taking ketone or placebo supplements after every training sessions and before going to sleep. During these 5 weeks, they will adhere to a prescribed training plan, consisting of 5 to 7 training sessions per week. Before, after and 1 week after the training camp, their exercise performance, EPO concentrations, hemoglobin mass and VO2max will be tested.

Conditions

• Hypoxia
• Exogenous Ketosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Placebo supplement	oral supplement containing: 16.4 grams of medium chained triglycerides, 1mM or sucrose octaacetate and water
DIETARY_SUPPLEMENT	Ketone ester supplement	Oral supplement containing: 25 grams of pure (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate ketone monoester drink

Timeline

• Start date: 2024-09-10
• Primary completion: 2024-10-15
• Completion: 2024-10-15
• First posted: 2024-09-19
• Last updated: 2024-09-19

Locations

1 site across 1 country: Belgium