NCT04288219

Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (estimated)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Trial of Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema

Detailed description

Patients in the Everest area will assessed for evidence of acute HAPE. Subjects will be randomized and assigned to standard care options or treatment with Non-Invasive Positive Pressure Ventilation.

Conditions

• High Altitude Pulmonary Edema
• Non-Invasive Positive Pressure Ventilation
• Hypoxia

Interventions

Type	Name	Description
DEVICE	Non-Invasive Positive Pressure Ventilation	Continuous positive airway pressure delivered by face mask at 10cmH2O
DRUG	Nifedipine	Nifedipine 30mg, Pharmacotherapy
OTHER	supplemental oxygen	supplemental oxygen

Timeline

• Start date: 2020-03-01
• Primary completion: 2021-06-01
• Completion: 2021-06-01
• First posted: 2020-02-28
• Last updated: 2020-09-03

Locations

1 site across 1 country: Nepal