| Not Yet Recruiting | The Effect of Lumify™ on Ocular Redness, Intraocular Pressure, and Eyelid Position in Glaucoma Patients NCT04007276 | Tulane University | Phase 4 |
| Not Yet Recruiting | Optic Nerve Head Strain in Non-glaucoma Subjects NCT07425535 | Johns Hopkins University | EARLY_Phase 1 |
| Not Yet Recruiting | Know Your Pressures NYC NCT05992415 | Columbia University | N/A |
| Not Yet Recruiting | Glaucoma Exercise as Medicine Study (GEMS). NCT05581498 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Rocklatan vs Latanoprost Post-DSLT NCT07465913 | Eye Centers of Southeast Texas | Phase 4 |
| Not Yet Recruiting | Efficacy and Safety of a Releasable Intraluminal Suture Technique to Reduce Hypotony Following Glaucoma Surger NCT07531199 | Hôpital Privé de la Baie | N/A |
| Not Yet Recruiting | Optimizing Graft Selection in Glaucoma Surgery: A Comparative Study of Sclera, Pericardium, and Corneal Tissue NCT07285616 | University of Alberta | N/A |
| Not Yet Recruiting | Artificial Intelligence-assisted Diagnosis in Ophthalmology NCT07497815 | Marisse Masis-Solano | — |
| Recruiting | Modified Trabeculectomy After Failure of Combined Phaco With GATT NCT07455786 | Assiut University | N/A |
| Not Yet Recruiting | Glaucoma Drop Aids Part 2 NCT06806332 | Boston Medical Center | N/A |
| Not Yet Recruiting | Impact of a Glaucoma Awareness Program on Treatment Adherence NCT07488234 | Seva Canada Society | N/A |
| Recruiting | Advancing Pediatric Retinal Imaging With Auto-aligned OCT NCT06841575 | Duke University | N/A |
| Not Yet Recruiting | Change in IOP Fluctuation After DSLT NCT07428668 | Ophthalmology Associates, Fort Worth | — |
| Recruiting | Automated Applanation Tonometry - Updated NCT07298356 | Duke University | N/A |
| Not Yet Recruiting | Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment NCT07341763 | University of Waterloo | N/A |
| Enrolling By Invitation | AI-Assisted Detection of Posterior Segment Diseases: DR, AMD, RVO, and Glaucoma NCT07318428 | Inje University | N/A |
| Recruiting | Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant NCT07495852 | Glaukos Corporation | Phase 3 |
| Recruiting | Glaucoma Screening to Enhance At-Risk Californians' Health NCT06854198 | University of California, San Francisco | N/A |
| Recruiting | Efficacy of Biofeedback Training for Glaucoma NCT07409077 | University Health Network, Toronto | N/A |
| Recruiting | Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use NCT07217678 | University of Miami | Phase 4 |
| Recruiting | Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies NCT07145073 | National Taiwan University Hospital | N/A |
| Not Yet Recruiting | Retinal Ganglion Cell Neuroprotection Under Prostaglandin Analogues NCT07074782 | Association for Innovation and Biomedical Research on Light and Image | — |
| Not Yet Recruiting | DSLT in Normal Tension Glaucoma (NTG) Asian Eyes NCT07300852 | Ngoc Nguyen Inc. | N/A |
| Enrolling By Invitation | Effectiveness of a Large Language Model-Based Educational Tool on Visual Field Test Reliability in Glaucoma Pa NCT07327242 | Stanford University | N/A |
| Not Yet Recruiting | Rocklatan Retinal Perfusion OCT Study NCT07174401 | Oregon Health and Science University | Phase 4 |
| Recruiting | Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2 NCT06934577 | University of Michigan | N/A |
| Not Yet Recruiting | Safety and Effectiveness of PreserFlo and XEN Stents With or Without Amniotic Membrane in Glaucoma Surgery NCT07143708 | Nova Scotia Health Authority | N/A |
| Not Yet Recruiting | High-throughput Large-model-based AI-assisted Diagnosis Using OCT NCT07249307 | Peking Union Medical College Hospital | — |
| Recruiting | Glaucoma Screening Using Artificial Intelligence Assisted Clinical Model in Singapore's Diabetic Eye Screening NCT07243665 | Singapore Eye Research Institute | N/A |
| Recruiting | Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02% NCT07209410 | Insight Eyecare Specialties, Inc. dba Vision Source Eyecare, | Phase 4 |
| Recruiting | Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass NCT07218796 | SpyGlass Pharma, Inc. | Phase 3 |
| Recruiting | Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertensio NCT07168902 | Bausch & Lomb Incorporated | Phase 2 |
| Recruiting | Implementing AI-based Glaucoma Screening Within Federally Qualified Health Centers NCT06629649 | University of Alabama at Birmingham | N/A |
| Enrolling By Invitation | Smart Soft Contact Lenses for Monitoring Glaucoma NCT07224542 | Indiana University | N/A |
| Recruiting | Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass NCT07218783 | SpyGlass Pharma, Inc. | Phase 3 |
| Recruiting | Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma NCT07354009 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Not Yet Recruiting | Nicotinamide Levels in Serum, Aqueous Humor, and Tear Film in Glaucoma and Correlations With Mitochondrial Dam NCT07006194 | Università degli Studi 'G. d'Annunzio' Chieti e Pescara | N/A |
| Recruiting | Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition NCT07364929 | National University of Singapore | N/A |
| Recruiting | Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy NCT06993597 | University of Maryland, Baltimore | — |
| Not Yet Recruiting | Multi-modal Intelligent Diagnosis System for Multiple Ophthalmic Diseases NCT07143851 | Beijing Hospital | — |
| Recruiting | To Study Ocular Outflow Dynamics of the Eye Using Intraoperative Tonographic Biometry and Assess Its Predictiv NCT07425496 | The New York Eye & Ear Infirmary | — |
| Completed | Study of an Investigational Product, QLS-111, Provided as an Eyedrop, for Treatment of Normal Tension Glaucoma NCT06030193 | Qlaris Bio, Inc. | Phase 2 |
| Enrolling By Invitation | Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty NCT07073937 | University of Utah | — |
| Recruiting | The Glaucoma and Retinopathy Screening Study NCT06882356 | Massachusetts Eye and Ear Infirmary | N/A |
| Recruiting | Electrical Stimulation for Vision Neuroenhancement in Glaucoma NCT06685211 | Stanford University | N/A |
| Recruiting | Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on Glaucoma NCT07119580 | National Taiwan University Hospital | — |
| Not Yet Recruiting | A Study Evaluating the Safety and Efficacy of MINIject S+ in Subjects With Open Angle Glaucoma NCT07009236 | iSTAR Medical | N/A |
| Active Not Recruiting | Visual Field Analysis With Artificial Intelligence NCT06920290 | Sight Intelligence Engineering Corporation | — |
| Not Yet Recruiting | Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus Tonometry NCT04024293 | Sensimed AG | N/A |
| Not Yet Recruiting | Strategies for Improving Linkage-to-Care After Eye Disease Screening NCT06943599 | University of California, San Francisco | N/A |
| Recruiting | Data Gathering for A10900 NCT07149740 | Optos, PLC | — |
| Active Not Recruiting | This Follow-up Extension Study is Aimed to Monitor the Long-term IOP-lowering Performance/Efficacy and Safety NCT07081347 | Sanoculis Ltd | N/A |
| Recruiting | Safety of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cata NCT07036510 | EyeD Pharma | Phase 1 |
| Recruiting | Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Imp NCT07075718 | Glaukos Corporation | Phase 2 / Phase 3 |
| Not Yet Recruiting | Study of Human Ocular Hemodynamics by Holography Dopple NCT06989996 | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | N/A |
| Recruiting | Glaucoma Laser Assessment of Stability and Sustainability NCT06963684 | Twin Cities Eye Consultants | N/A |
| Recruiting | Metformin as a Neuroprotective Therapy for Glaucoma NCT05426044 | Christopher Kai Shun Leung | Phase 2 |
| Active Not Recruiting | Pilot Study on a New Self Adjustable Glaucoma Drainage Device NCT07480603 | Rheon Medical SA | Phase 1 |
| Recruiting | The Role of Music in Enhancing Attention During Visual Field Exams for Pediatric Glaucoma Patients NCT06971588 | Johns Hopkins University | N/A |
| Recruiting | Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients NCT06991712 | Christopher Kai Shun Leung | Phase 2 |
| Recruiting | Is There a Response of Glaucoma to Baduanjin Exercise in Elders? NCT07163676 | Cairo University | N/A |
| Completed | Awareness and Perception of Glaucoma Among Patients Attending Ophthalmology OPD in a Tertiary Care Hospital. NCT07153588 | Bacha Khan Medical College | — |
| Completed | Effect of Kron (Citicoline and Nicotinamide Oral Solution) on Patients With Open-angle Glaucoma NCT06333236 | ASST Santi Paolo e Carlo | N/A |
| Recruiting | Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years NCT07460791 | Johannes Gutenberg University Mainz | — |
| Recruiting | Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glau NCT06682962 | Okuvision GmbH | N/A |
| Recruiting | Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma NCT07322965 | Institut Catala de Retina | N/A |
| Enrolling By Invitation | The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal Dystrophy NCT06969586 | University Hospital Dubrava | — |
| Enrolling By Invitation | The Effect of ROCK Inhibitors on Corneas of Patients With Glaucoma and Pseudophakic Bullous Keratopathy (PBK) NCT06960629 | University Hospital Dubrava | — |
| Not Yet Recruiting | Functional Assessments in Vision Impairment NCT06908161 | Center for Eye Research Australia | — |
| Recruiting | Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract NCT06844292 | Medical University of Graz | N/A |
| Recruiting | Efficacy of Direct Selective Laser Trabeculoplasty in Clinical Practice in Patients with Glaucoma NCT06808633 | Clínica Rementería | — |
| Not Yet Recruiting | Comparison Between Handheld Rebound Tonometer and Applanation Tonometer in IOP Measurement in Paediatric Glauc NCT06766799 | Sohag University | — |
| Completed | 24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring NCT06689696 | Smartlens, Inc. | — |
| Recruiting | Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Proced NCT05694858 | Universiti Kebangsaan Malaysia Medical Centre | Phase 1 / Phase 2 |
| Recruiting | A Trial of Hydrus Microstent Versus Goniotomy NCT06289491 | Massachusetts Eye and Ear Infirmary | N/A |
| Completed | Improved Efficacy of Selective Laser Trabeculoplasty With the Addition of Rocklatan Post-treatment vs Artifici NCT06819046 | Colorado Ophthalmology Associates PC | — |
| Completed | Long-term Outcomes of Glaucoma Surgery in a Real-life Setting: the Agora Registry Study NCT06829810 | University Hospital, Bordeaux | — |
| Recruiting | Efficacy and Safety of the ELIOS Laser in Combined Cataract and Glaucoma Surgery NCT06760169 | Hôpital Privé de la Baie | N/A |
| Recruiting | "My Eyes, My Light": Amar Chokh, Amar Alo NCT07135570 | Data Yakka, Inc. | — |
| Enrolling By Invitation | Electrical Stimulation of the Optic Nerve in Patients With Glaucoma. NCT06693882 | Glaucoma Center of San Francisco | N/A |
| Recruiting | A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma NCT06792422 | Glostrup University Hospital, Copenhagen | Phase 4 |
| Recruiting | Glaucoma Related Quality of Life NCT07510087 | Marc Toeteberg-Harms | — |
| Not Yet Recruiting | Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery NCT06680245 | St. Joseph's Healthcare Hamilton | Phase 3 |
| Enrolling By Invitation | Efficacy and Safety of XEN63 Gel Implant NCT06844240 | Mario Stirpe | — |
| Completed | Comparison of Visual Field Assessments Between Three Perimeters NCT06539715 | Gainesville Eye Associates | Phase 4 |
| Enrolling By Invitation | Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive Patients NCT06827535 | Mario Stirpe | — |
| Recruiting | Low Intraocular Pressure Cataract Surgery With Zeiss Quatera in Glaucoma Patients NCT06712758 | Visionair Oogzorg | — |
| Recruiting | Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) Shunt NCT06691555 | Davinci LTD | — |
| Not Yet Recruiting | The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patien NCT06526416 | Benha University | — |
| Completed | Comparison of Two OCT Device RNFL and GCIPL Measurements in Mild, Moderate, and Severe Glaucoma NCT07350304 | Twin Cities Eye Consultants | — |
| Recruiting | Community Based Treatment for (ComBaT) Glaucoma NCT06124521 | University of Michigan | N/A |
| Recruiting | Tolerability of an Anesthesia-free Tonometer Tip NCT06585423 | Duke University | N/A |
| Active Not Recruiting | A Real-World Study of Interventional Clinical Outcomes in Patients With Open Angle Glaucoma and Other Chronic NCT07216677 | Interstat LLC | — |
| Completed | An App-based Instructional Platform to Improve Eye Drop Recall NCT06045390 | University of California, San Francisco | N/A |
| Not Yet Recruiting | Glaucoma Algorithm Validation Study in African Population - the MAGIC Study NCT06552247 | Centro Hospitalar Universitário Lisboa Norte | N/A |
| Completed | Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients NCT06394973 | Laboratoires Thea | Phase 2 |
| Recruiting | Perimetric Testing With Virtual Reality NCT06549010 | Envision Health Technologies, Inc. | N/A |
| Completed | Optic Nerve Perfusion Following Treatment with Latanoprost Versus Brimionidin Tartrate NCT06730516 | Zagazig University | EARLY_Phase 1 |
| Unknown | Evaluation of Visual Training System in Patients With Glaucoma NCT06433102 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Fixating the Plate of Ahmed Valve to the Sclera Using a Flanged Prolene Suture NCT06722794 | Zagazig University | N/A |
| Recruiting | Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice NCT07015034 | University of Copenhagen | N/A |
| Recruiting | Barcelona Esquerra Glaucoma Artificial Intelligence-based Screening Program (BEGAS) NCT06353542 | Hospital Clinic of Barcelona | N/A |
| Unknown | Impact of Breathing Exercises and Meditation on Reducing Stress and Improving Quality of Life of Glaucoma Pati NCT06144138 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Recruiting | Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma NCT06274593 | Nantes University Hospital | — |
| Completed | Qlaris Study of QLS-111 in Combination With a PGA for OAG and/or OHT Patients NCT06249152 | Qlaris Bio, Inc. | Phase 2 |
| Active Not Recruiting | Anterior Segment Optical Coherence Tomography Microstent Positioning NCT06666751 | University of Utah | — |
| Terminated | Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension NCT04500574 | Massachusetts Eye and Ear Infirmary | Phase 1 |
| Enrolling By Invitation | Nicotinamide Supplementation in Glaucoma NCT06731582 | Singapore Eye Research Institute | Phase 3 |
| Not Yet Recruiting | Efficacy of 20% Autologous Serum Drops in the Treatment of Corneal Epitheliopathy Associated With Antihyperten NCT06294015 | Université de Sherbrooke | Phase 4 |
| Completed | Glaucoma Evaluation With the P200TE NCT06305481 | Optos, PLC | N/A |
| Completed | EVALUATION of CATS TONOMETER PRISM in LASIK SUBJECTS NCT06266351 | Intuor Technologies, Inc. | — |
| Withdrawn | Persistence of Glaucoma Patients With Web-Browser-Based Visual Field Test NCT05690152 | Andrew Pouw, MD | N/A |
| Completed | TRK-3 Conformance to Standards for Tonometers NCT06247072 | Topcon Corporation | — |
| Recruiting | Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment NCT06243497 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Completed | Sponge Application of MMC Versus Suntenon Injection in Trabeculectomy NCT06925412 | Al-Azhar University | N/A |
| Completed | Effect of Fixed Combination Citicoline Homotaurine and Pyrroloquinoline Quinone on Pattern-electroretinogram i NCT06431113 | Fondazione IRCCS Policlinico San Matteo di Pavia | Phase 3 |
| Recruiting | Optimize Pediatric OCT Imaging NCT06139523 | Duke University | — |
| Completed | Efficacy and Safety of Minimally Invasive Micro-Sclerostomy (MIMS) in Glaucoma Surgery NCT06213805 | Hôpital Privé de la Baie | N/A |
| Active Not Recruiting | VividWhite Glaucoma Implant (VW-51) Pivotal Study NCT06176170 | VividWhite Pty Ltd | N/A |
| Completed | Glaucoma Screening NCT06186388 | Cape Fear Eye Institute | N/A |
| Recruiting | Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study NCT06492538 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Completed | EX-PRESS® P-50 and EX-PRESS® P-200 NCT06119178 | Alcon Research | — |
| Completed | Nurse-led Educational Intervention on Patients With Glaucoma With Low Health Literacy NCT06706089 | Hellenic Mediterranean University | N/A |
| Completed | The Effects of a Large Language Model on Clinical Questioning Skills NCT06229379 | Sun Yat-sen University | N/A |
| Terminated | Screening Protocol NCT06135727 | Topcon Corporation | — |
| Unknown | Impact of Breathing Exercises and Meditation on Improving Quality of Life in Glaucoma Patients NCT05960513 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Unknown | Impact of Meditation on Improving Quality of Life Among Glaucoma Patients: An Electronic Pilot Feasibility Stu NCT05697094 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Active Not Recruiting | Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared t NCT06120842 | SpyGlass Pharma, Inc. | Phase 1 / Phase 2 |
| Unknown | Evaluation of New Head-mounted Visual Aids Among Patients With Low Vision NCT06076720 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Suspended | Impact of an Educational Video on Satisfaction After Glaucoma Surgery NCT03958929 | Sun Yat-sen University | N/A |
| Completed | Swept Source OCT Imaging With the DREAM VG-OCT NCT05876689 | Robert T. Chang, MD | — |
| Unknown | Comparison of Aqueous Humor Adipokines in Glaucoma Patients and Healthy Controls NCT06190119 | Peking University | — |
| Unknown | Buyang Huanwu Decoction and Normal Tension Glaucoma NCT06054763 | China Medical University Hospital | N/A |
| Recruiting | Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE NCT06000865 | The Hong Kong Polytechnic University | N/A |
| Completed | Automatic Evaluation of the Anterior Chamber Angle Width by a New Non-contact Optical Device NCT06278597 | Fondazione G.B. Bietti, IRCCS | N/A |
| Recruiting | Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle G NCT06057051 | Glaukos Corporation | N/A |
| Unknown | Glaucoma Screening With Artificial Intelligence NCT06012058 | The University of Hong Kong | N/A |
| Unknown | Evaluation of Patients' Requirements for Improved Advice and Guidance on Vision Standards for Driving in Glauc NCT05968547 | Manchester University NHS Foundation Trust | — |
| Unknown | Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression NCT05940623 | The University of Hong Kong | N/A |
| Recruiting | Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial NCT05924477 | University of Pennsylvania | N/A |
| Completed | Correlation of Structure and Function in Glaucoma NCT05954637 | Vienna Hospital Association | — |
| Unknown | OphtAI Diagnostic Performance Validation for Automated Screening of Eye Diseases NCT05752045 | Evolucare Technologies | N/A |
| Recruiting | Acupuncture as Adjuvant Therapy for Glaucoma - Protocol for a Randomized Controlled Trial NCT05753137 | China Medical University Hospital | N/A |
| Completed | Evaluation of The Performance of Retinow AI Software NCT06645964 | Retinow Health Technologies and R&D Industry Joint Stock Company | — |
| Not Yet Recruiting | Prospective Electronic Polygenic Risk Study - Second Phase NCT05175651 | Scripps Translational Science Institute | N/A |
| Unknown | Evaluate the Efficacy and Safety of Glaucoma Implant in Primary Open Angle Glaucoma NCT05892185 | Mingche Biotechnology CO., LTD | N/A |
| Unknown | Anterior Lens Capsule as a Spacer in the Deep Sclerectomy _ Phacoemulsification NCT05906212 | Shahid Beheshti University of Medical Sciences | N/A |
| Recruiting | Glaucoma Rehabilitation Using ElectricAI Transcranial Stimulation (GREAT) - Randomized Controlled Trial Using NCT05874258 | The Hong Kong Polytechnic University | N/A |
| Unknown | MicroPulse TLT - UK Study NCT05593354 | Imperial College Healthcare NHS Trust | — |
| Completed | Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT NCT06524661 | Minia University | — |
| Enrolling By Invitation | Glaucoma Portugal Screening Trial NCT05875090 | Centro Hospitalar Universitário Lisboa Norte | N/A |
| Not Yet Recruiting | Evaluation of a Novel Head-Mounted Device for Glaucoma Testing: A Proof-of-Concept Study NCT05030714 | Brennan Eadie | N/A |
| Recruiting | Ocular Blood Flow Imaging for Glaucoma Assessment NCT05726058 | University of Maryland, Baltimore | N/A |
| Terminated | Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp Configurations NCT05686421 | NYU Langone Health | N/A |
| Active Not Recruiting | Safety of Topical Insulin Drops for Open-angle Glaucoma NCT04118920 | Centre hospitalier de l'Université de Montréal (CHUM) | Phase 1 |
| Active Not Recruiting | Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With NCT07154810 | SpyGlass Pharma, Inc. | — |
| Completed | Prevalence of Glaucoma in Belgium: a Multicenter National Trial NCT05703724 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus Images NCT06213896 | Ural Telekomunikasyon Sanayi Ticaret Anonim Sirketi | — |
| Unknown | Implantation of Capsular Tension Ring in Primary Angle Closure Patients With Zonular Laxity or Dialysis NCT05542290 | Beijing Tongren Hospital | N/A |
| Recruiting | Electrical Stimulation for the Treatment of Glaucoma NCT05626491 | Stanford University | N/A |
| Recruiting | Electrical Stimulation for the Treatment of Optic Neuropathies NCT05626426 | Stanford University | N/A |
| Completed | Comparing NGENUITY vs Conventional Microscope in a New Hydrus User NCT05529966 | Stanford University | N/A |
| Recruiting | Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical H NCT06017362 | Barbara Burgos Blasco | Phase 4 |
| Unknown | Exercise Intervention in Primary Open-angle Glaucoma NCT05704777 | Universidad de Granada | N/A |
| Completed | SmartSystem Virtual Reality Headset Perimeter Versus Humphrey HFA-III Perimeter NCT05674890 | Andrew Pouw, MD | N/A |
| Unknown | Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases NCT06200727 | Lei Du | N/A |
| Unknown | ISNT Rule in Normal Population NCT05575154 | Assiut University | — |
| Completed | Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due NCT05495269 | Qlaris Bio, Inc. | Phase 2 |
| Terminated | Automated Applanation Tonometry NCT05235321 | Duke University | N/A |
| Unknown | P200TE and Predicate Agreement and Precision Study NCT05624593 | Optos, PLC | N/A |
| Recruiting | Hyperbaric Oxygen Therapy for Optic Neuropathies NCT06128720 | Stanford University | N/A |
| Recruiting | Endothelial Cell Loss in Pseudophakic Patients Receiving a Paul Glaucoma Drainage Device With Its Tube Inserte NCT05500469 | Oogziekenhuis Rotterdam | N/A |
| Unknown | The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechan NCT06340061 | Henan Provincial People's Hospital | — |
| Recruiting | Comparing the Baerveldt and Paul Glaucoma Drainage Devices and Their Effects on the Corneal Endothelium NCT05344651 | Oogziekenhuis Rotterdam | N/A |
| Terminated | Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma NCT05273385 | University of California, San Francisco | N/A |
| Completed | Comparison of Phaco-Trabeculectomy and MSICS-Trab in Cataract and Glaucoma Patients NCT06739343 | Emeka John Dingwoke | N/A |
| Unknown | Efficacy of Nicotinamide on Retinal Ganglion Cell Functions in Glaucoma Patients NCT06078605 | CHA University | N/A |
| Unknown | Effect of Intraocular Tamponade on Visual Perception NCT05543018 | Benha University | N/A |
| Completed | Optic Disc Photograph Collection Study NCT05532410 | Optos, PLC | N/A |
| Terminated | P200TE Agreement and Precision Study NCT05536401 | Optos, PLC | N/A |
| Completed | Assessment of an Automated Optical Coherence Tomography and Camera : Effectiveness of Vision-700 NCT06496763 | Crystalvue Medical Coporation | — |
| Unknown | Paul Glaucoma Implant Versus Ahmed Glaucoma Valve in Childhood Glaucoma NCT05797350 | Al Watany Eye Hospital | N/A |
| Recruiting | Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices NCT05523622 | State University of New York at Buffalo | N/A |
| Unknown | Glaucoma Telemedicine Screening NCT05446363 | University Hospital Olomouc | — |
| Active Not Recruiting | Safety Assessment of T4090 Eye Drops in Ocular Hypertensive or Glaucomatous Patients. NCT05389267 | Laboratoires Thea | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety Assessment of T4032 (Unpreserved Bimatoprost 0.01%) Versus Lumigan® 0.01% in Ocular Hypert NCT05397600 | Laboratoires Thea | Phase 3 |
| Completed | A Post-market Clinical Study to Collect Safety and Performance Data on Johnson & Johnson Surgical Vision Produ NCT05394324 | Johnson & Johnson Surgical Vision, Inc. | — |
| Recruiting | Retinal Blood Flow and Autoregulation NCT05344274 | University of Maryland, Baltimore | Phase 4 |
| Recruiting | The Glaucoma Nicotinamide Trial NCT05275738 | Umeå University | N/A |
| Recruiting | Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma NCT05264818 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression NCT05801471 | Centervue SpA | — |
| Completed | Effects of Melatonin Supplementation on Sleep Quality in Patients With Advanced Glaucoma NCT06868745 | University of Sao Paulo | N/A |
| Unknown | Morphological Changes of Ciliary Body and Trabecular Meshwork NCT05352854 | Yune Zhao | N/A |
| Unknown | Efficiency of Intraoperative Optical Coherence Tomography (iOCT) NCT05232539 | Somich, s.r.o. | N/A |
| Recruiting | NorMIGS - a Study of Micro-invasive Glaucoma Surgery NCT05340647 | Oslo University Hospital | — |
| Completed | Evaluation of the Safety and Effectiveness of the Bimatoprost Implant System / IOL Combination in Patients Wit NCT07154797 | SpyGlass Pharma, Inc. | N/A |
| Unknown | Accuracy of Handheld and Non-contact Tonometry NCT05352906 | Benha University | N/A |
| Completed | Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients NCT05654493 | Mayo Clinic | — |
| Completed | The Minimally Invasive Micro Sclerostomy (MIMS®) System is Intended for the Reduction of Elevated Intraocular NCT07051174 | Sanoculis Ltd | N/A |
| Recruiting | Topical Insulin for Glaucoma NCT05206877 | Stanford University | Phase 1 |
| Completed | Rocklatan® Evaluation NCT05283395 | Aerie Pharmaceuticals | Phase 4 |
| Completed | Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives NCT05319470 | Democritus University of Thrace | — |
| Withdrawn | Satisfaction After Glaucoma Surgery in Rural China NCT02629237 | Sun Yat-sen University | N/A |
| Unknown | Phacoemulsification in Acute Congestive Glaucoma NCT05289453 | Hany Mahmoud | N/A |
| Completed | Study to Evaluate Drug-drug Interaction, Safety and Tolerability in Case of the Co-administration of D565 and NCT05207761 | Chong Kun Dang Pharmaceutical | Phase 1 |
| Suspended | Feasibility of Visual Field Testing With a Virtual Reality Headset NCT03748654 | Brennan Eadie | N/A |
| Unknown | Evaluation of Minimal Invasive Glaucoma Surgery NCT04572880 | Medical University of Graz | N/A |
| Withdrawn | Surgical Retinotomy for the Treatment of Glaucoma NCT03798145 | Stanford University | N/A |
| Unknown | High Resolution Optical Coherence Tomography NCT05130385 | Insel Gruppe AG, University Hospital Bern | — |
| Active Not Recruiting | Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor NCT05127551 | Glaukos Corporation | N/A |
| Completed | iCare HOME2 Clinical Trial NCT05162989 | Icare Finland Oy | N/A |
| Withdrawn | Study Comparing the Kinetics of Endothelial Cell Loss Associated With the XEN® Implant Versus Traditional Filt NCT04781283 | Fondation Hôpital Saint-Joseph | N/A |
| Unknown | Macular Pigment Optical Density in Primary Angle-closure Disease NCT05251792 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Unknown | XEN45 in the Treatment of Chinese Patients With Primary Open-angle Glaucoma NCT05130554 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Evaluation of Nanodropper-mediated Microdrops vs. Standard Drops of 0.5% Timolol Maleate in Glaucoma Patients NCT05181046 | Nanodropper, Inc. | N/A |
| Unknown | Kahook Dual Blade Ab-interno Trabeculotomy Versus ab Externo Viscotrabeculotomy in Primary Congenital Glaucoma NCT05115708 | Mansoura University | N/A |
| Recruiting | Optimal Non-invasive Brain Stimulation for Peripheral Vision NCT04846140 | The Hong Kong Polytechnic University | N/A |
| Completed | Patient Performance on Virtual Reality Visual Field Devices as Compared to Standard of Care NCT04994457 | University of Miami | — |
| Completed | A Virtual Reality Platform Simulating Visual Impairment for Testing of Electronic Travel Aids and Performing O NCT05135195 | NYU Langone Health | N/A |
| Completed | A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101 NCT04947124 | Qlaris Bio, Inc. | Phase 2 |
| Completed | Nicotinamide and Glaucoma NCT05916066 | Umeå University | N/A |
| Unknown | Ahmed Valve Implantation Coated With Poly Lactic -Co-glycolic Acid (PLGA) Saturated With Mitomycin-C in the Ma NCT04735601 | Sohag University | Phase 3 |
| Unknown | Visual Field Progression and RNFL Change After PreserFlo MicroShunt Implantation NCT06174324 | Klinikum Klagenfurt am Wörthersee | — |
| Completed | Comparison of Efficacy and Ocular Surface Assessment Between BRIDIN-plus and Combigan in Glaucoma or Ocular Hy NCT06078592 | CHA University | Phase 4 |
| Unknown | Application of Innovative Non-Invasive Neuroprotective Technology in Cardiac Surgery and Ophthalmology NCT04943458 | Milda Svagzdiene | — |
| Recruiting | Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet C NCT04957329 | Rigshospitalet, Denmark | Phase 4 |
| Active Not Recruiting | Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure ( NCT05024695 | iSTAR Medical | N/A |
| Unknown | AGV Implantation With Ologen in Pediatric Glaucomas NCT05014386 | Mansoura University | N/A |
| Completed | Outflow Facility AIT vs Microshunt NCT05548959 | Wuerzburg University Hospital | N/A |
| Active Not Recruiting | A Study of Yutiq Steroid Insert During Glaucoma Tube Implant Surgery NCT04918121 | Sanjay Asrani | EARLY_Phase 1 |
| Terminated | Development and Validation of a Model to Predict Fast Progression in Glaucoma NCT04454190 | Duke University | — |
| Completed | Deep Sclerectomy vs Xen in Solo Procedure NCT05201378 | Fondation Hôpital Saint-Joseph | — |
| Unknown | Investigating Multimodally Endothelial Dysfunction in Ocular and Systemic Disease NCT06485128 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Unknown | Development and Implementation of an Educational Program to Enhance Adherence to Glaucoma Treatment NCT04245163 | Cyprus University of Technology | N/A |
| Completed | The Effect of Direct Cyclophotocoagulation Using Endolaser in Silicon Induced Glaucoma: a Pilot Study. NCT05231252 | Kafrelsheikh University | N/A |
| Active Not Recruiting | Dual Intravitreal Implantation of NT-501 Encapsulated Cell Therapy for Glaucoma NCT04577300 | Stanford University | Phase 2 |
| Completed | Impact of Self-tonometry on Glaucoma Treatment Decision. NCT04888156 | St. Erik Eye Hospital | — |
| Completed | Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc Images NCT04972695 | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | — |
| Recruiting | Evaluation of Different Perimetric Grids to Detect Central Visual Field Defect in Glaucoma Patients with Reduc NCT06227611 | Fondazione G.B. Bietti, IRCCS | — |
| Completed | Study of Application of Pulse Electrical Stimulation Around Eye in Glaucoma Patients NCT05159414 | Nu Eyne Co., Ltd. | N/A |
| Unknown | Effect of Antihypertensive Drugs on Glaucoma Patients NCT04943107 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Withdrawn | Augmented Macular Pigment-containing Nutraceutical and Central Visual Function NCT04676126 | University of the Incarnate Word | Phase 4 |
| Completed | To Evaluate the Effect of Ginkgo Biloba Extract on Optic Nerve Head Perfusion Examined Using OCTA NCT04846179 | Nova Scotia Health Authority | Phase 4 |
| Completed | The Support, Educate, Empower (SEE) Program NCT04735653 | University of Michigan | N/A |
| Completed | Supracapsular Ahmed Glaucoma Valve Plate Delivery Technique for Management of Encapsulated Bleb in Pediatric P NCT04931290 | Mansoura University | N/A |
| Recruiting | Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications NCT04354545 | University of California, Los Angeles | — |
| Completed | The Water Drinking Test in Glaucoma Study NCT05283031 | Imperial College London | — |
| Active Not Recruiting | Triplenex (triple Fixed Combination) Use Evaluation in Patients with Glaucoma NCT06761313 | Federal University of São Paulo | Phase 4 |
| Completed | Self Tonometry and Transfer of Glaucoma Patients' Data for Improving the Supply Situation NCT04698876 | University Hospital Muenster | N/A |
| Unknown | Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics NCT04682054 | The First Affiliated Hospital with Nanjing Medical University | N/A |
| Terminated | Reliability and Reproducibility of the Eye Check Tonometer NCT04639947 | Duke University | N/A |
| Completed | Evaluation of Retina in Patients With Glaucoma Using Topical Prostaglandins Undergoing Trabeculectomy Surgery NCT06000280 | Universidade Federal de Goias | N/A |
| Completed | Vivity Outcomes in Patients With Early Stage Glaucoma NCT04670575 | Vance Thompson Vision | — |
| Terminated | Laser Dosage in MicroPulse TransScleral CycloPhotocoagulation NCT04709679 | State University of New York at Buffalo | N/A |
| Completed | Analysis of Conjunctival Changes as Indicators for Ab-interno Gelatin Microstent Implantation Surgery Outcomes NCT04727411 | Hospital Clinic of Barcelona | N/A |
| Completed | The Baerveldt Versus ClearPath Comparison Study NCT04468633 | Duke University | N/A |
| Completed | Optic Nerve Head Shape as a Predictor of the Formation of Acquired Pits of the Optic Nerve (APONs) NCT04610008 | Cardiff and Vale University Health Board | — |
| Completed | Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance NCT04412096 | Ohio State University | Phase 4 |
| Unknown | Effect of Combining Yoga to TENS on Diabetic Glaucoma NCT04645992 | Cairo University | N/A |
| Completed | Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits NCT04328207 | University of Alabama at Birmingham | N/A |
| Unknown | NSAID vs Steroid in Trabeculectomy Wound Management NCT03751059 | Cindy Hutnik | Phase 4 |
| Completed | Phaco-Trabeculotomy Vs Phaco-Trabeculectomy NCT04683055 | Assiut University | N/A |
| Completed | Comparison of Intraocular Pressure Measurements Between Reichert Tono-Vera Tonometer and Goldmann Tonometry NCT04360369 | Reichert, Inc. | N/A |
| Unknown | Triamcinolone Injections for Persistent Choroidal Effusions Post Glaucoma Surgery NCT02917564 | Sunnybrook Health Sciences Centre | Phase 4 |
| Completed | A First-In-Human Clinical Trial to Evaluate the Safety, Effectiveness and Surgical Characteristics of CADENCE NCT05131087 | New World Medical, Inc. | N/A |
| Completed | A Universal Eye Drop Adherence Monitor to Measure and Improve Adherence to Ocular Medications NCT03506568 | Universal Adherence LLC | N/A |
| Withdrawn | Effect of Negative Pressure on Pattern Electroretinography Readings NCT04433702 | Vance Thompson Vision | N/A |
| Unknown | Vitreous Detachment and Glaucoma Progression NCT04719871 | University Hospital, Montpellier | — |
| Terminated | Assessment of Visual Function in Ophthalmic Disorders Using Virtual Visual Field Analysis NCT04110015 | New York City Health and Hospitals Corporation | — |
| Completed | Assessment of the Impact of an add-on and Its Smartphone Application on the Daily Management of Glaucoma NCT04552964 | Laboratoires Thea | N/A |
| Active Not Recruiting | iStent Inject New Enrollment Post-Approval Study NCT04624698 | Glaukos Corporation | N/A |
| Completed | Glaucoma Surgery Using the ViaLase Laser System NCT04949802 | Vialase, Inc. | N/A |
| Unknown | Efficacy and Safety of Non-resorbable Uveoscleral Implant Versus Absorbable Collagen Matrix in Non-perforating NCT04586738 | Germans Trias i Pujol Hospital | N/A |
| Terminated | Anterior-segment OCT (AS-OCT) and Intraoperative OCT (iOCT) for Trans- Conjunctival Needle Revision (TCNR) NCT05790408 | Northwestern University | N/A |
| Completed | Baerveldt 350 vs Ahmed ClearPath 250 for the Treatment of Glaucoma NCT04542616 | State University of New York at Buffalo | N/A |
| Completed | Screening and Intervention for Glaucoma and Eye Health Through Telemedicine NCT04274764 | University of Michigan | N/A |
| Unknown | OCT Angiography in the Glaucoma Diagnosis NCT04437446 | Fondation Hôpital Saint-Joseph | N/A |
| Completed | Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics NCT04475900 | Technische Universität Dresden | — |
| Unknown | Predicting the Effect of Laser Peripheral Iridotomy NCT04495491 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Completed | Comparative Study of the Cornea/Anterior Segment OCT CASIA2 and the RTVue XR OCT Avanti With AngioVue Software NCT04486976 | Tomey Corporation | N/A |
| Unknown | Vienna Preserflo Cohort Study NCT04541524 | Medical University of Vienna | — |
| Completed | Comparison of Topical Anesthesia and Analgosedation in Micropulse Transscleral Glaucoma Treatment NCT04448080 | University of Zurich | N/A |
| Unknown | Mirtogenol and Bimatoprost on IOP in Hispanics With Open-Angle Glaucoma NCT04380025 | University of Puerto Rico | N/A |
| Unknown | Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears) NCT04339907 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Terminated | Study of the Beacon Aqueous Microshunt in Patients With Refractory Glaucoma NCT04072016 | MicroOptx | N/A |
| Completed | iCare® Home vs Goldmann Applanation Tonometry NCT04911387 | St. Erik Eye Hospital | — |
| Withdrawn | Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma. NCT04334499 | The University of Texas Medical Branch, Galveston | — |
| Completed | Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glauco NCT04773106 | Implandata Ophthalmic Products GmbH | N/A |
| Completed | Changes in Corneal Endothelial Cell Density After Transscleral ab Interno Glaucoma Gel Stent Implantation NCT04547036 | Paracelsus Medical University | — |
| Recruiting | The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis NCT04232982 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | Agreement and Precision Study of the Nidek Mirante NCT04318132 | Nidek Co. LTD. | N/A |
| Terminated | Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery NCT04200651 | The New York Eye Surgery Center | Phase 4 |
| Completed | Augmented Reality Mobile Application for Glaucoma Education in the South Bronx NCT04421859 | Bronx-Lebanon Hospital Center Health Care System | N/A |
| Completed | Micropulse Transscleral Diode Laser Cyclophotocoagulation (MP-TSCPC) as a Treatment Modality for Glaucoma Pati NCT05299281 | Benha University | N/A |
| Completed | Advancing Understanding of Transportation Options NCT04141891 | University of Colorado, Denver | N/A |
| Unknown | Study on Intraocular Structural Parameters and Surgical Effect Before and After the Onset of Malignant Glaucom NCT04220879 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Completed | Effect of Vitamin Supplementation in Glaucoma Patients NCT05080153 | Devogelaere Vision | — |
| Completed | Effects of Topical Low Dose Preservative-free Hydrocortisone on Intraocular Pressure NCT04536129 | University of Molise | N/A |
| Completed | Interval Intraocular Pressure in Intravitreal Injection Study NCT04868175 | The University of Hong Kong | N/A |
| Unknown | Bimodal and Coaxial High Resolution Ophtalmic Imaging NCT04620876 | Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts | N/A |