| Recruiting | Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant Glaucoma | Phase 3 | 2026-02-17 |
| Recruiting | Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With K Keratoconus | Phase 2 | 2025-12-23 |
| Recruiting | Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg Open Angle Glaucoma (OAG), Ocular Hypertension (OH) | — | 2025-12-17 |
| Recruiting | Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis Demodex Blepharitis | Phase 2 | 2025-12-05 |
| Recruiting | Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Imp Glaucoma | Phase 2 / Phase 3 | 2025-06-12 |
| Recruiting | Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery Alone Glaucoma, Open-angle, Ocular Hypertension (OHT), Phacoemulsification Cataract Surgery | Phase 4 | 2025-01-13 |
| Unknown | Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension Open Angle Glaucoma, Ocular Hypertension | Phase 2 | 2023-11-15 |
| Recruiting | Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone Glaucoma, Open-Angle | Phase 3 | 2023-09-14 |
| Active Not Recruiting | Travoprost Intraocular Implant in Conjunction With Cataract Surgery Open Angle Glaucoma, Ocular Hypertension | Phase 3 | 2023-09-11 |
| Recruiting | Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle G Glaucoma | N/A | 2023-09-01 |
| Recruiting | A Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With PCED Persistent Corneal Epithelial Defect | Phase 2 | 2023-08-17 |
| Recruiting | Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus Progressive Keratoconus | Phase 1 / Phase 2 | 2022-03-08 |
| Completed | Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia Presbyopia | Phase 2 | 2022-01-03 |
| Completed | Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease Dry Eye Disease, Kerato Conjunctivitis Sicca | Phase 2 | 2022-01-03 |
| Active Not Recruiting | Clinical Study of Glaukos® Trabecular Micro-Bypass System Model iS3 Infinite Vs. Competitor Glaucoma, Glaucoma, Open-Angle | N/A | 2021-11-27 |
| Completed | Performance of the Travoprost Intraocular Implant Glaucoma, Open-Angle, Ocular Hypertension | Phase 2 | 2021-03-10 |
| Completed | Study of Exchange of Travoprost Intraocular Implant Open Angle Glaucoma | Phase 2 | 2020-11-19 |
| Active Not Recruiting | iStent Inject New Enrollment Post-Approval Study Glaucoma, Open-Angle, Glaucoma | N/A | 2020-09-22 |
| Terminated | NEXAGON for the Treatment of Corneal Persistent Epithelial Defects Following Severe Ocular Injuries Corneal Persistent Epithelial Defect | Phase 2 | 2020-06-30 |
| Unknown | iStent Inject Trabecular Micro-Bypass System Continuation Post-Approval Study Glaucoma, Open-Angle | — | 2020-01-15 |
| Completed | Clinical Study Comparing Two Models of a Travoprost Intraocular Implant Glaucoma, Open-Angle, Ocular Hypertension | Phase 3 | 2018-09-17 |
| Completed | Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Soluti Glaucoma, Open-Angle, Ocular Hypertension | Phase 3 | 2018-07-26 |
| Unknown | Investigation of the Glaukos® Trabecular Micro-Bypass System, Model iS3, in Subjects With Refractory Glaucoma Glaucoma | N/A | 2018-07-10 |
| Completed | Open-Angle Glaucoma Subjects With Cataract Treated With Cataract Surgery Plus One iStent and One iStent Supra Glaucoma, Open-Angle | N/A | 2018-05-01 |
| Completed | Study to Evaluate the Safety and Efficacy of Epi-on Corneal Cross-linking in Eyes With Progressive Keratoconus Progressive Keratoconus | Phase 3 | 2018-04-06 |
| Terminated | iStent Inject in OAG Subjects on 2 Pre-op Topical Ocular Hypotensive Medications Primary Open Angle Glaucoma (POAG) | N/A | 2018-02-27 |
| Unknown | Observational Registry to Assess the Durability of Effect of CXL in Patients With Corneal Ectasia After Refrac Corneal Ectasia | — | 2017-10-04 |
| Terminated | A Prospective Evaluation of Glaucoma Subjects Treated With Two Second Generation iStents and One iStent Supra Glaucoma, Open-Angle | N/A | 2017-08-01 |
| Completed | Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution Glaucoma Open-angle | Phase 2 | 2016-03-29 |
| Terminated | Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty Primary Open-Angle Glaucoma | N/A | 2014-12-16 |
| Terminated | Safety and Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus Keratoconus | Phase 3 | 2013-11-01 |
| Completed | Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket Registry Primary Open-angle Glaucoma | — | 2013-09-01 |
| Terminated | Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Hyperopia, Hyperopic Astigmatism | Phase 1 / Phase 2 | 2013-08-01 |
| Unknown | Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction Wi Primary Open Angle Glaucoma | N/A | 2013-07-01 |
| Completed | Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket Primary Open Angle Glaucoma | — | 2013-07-01 |
| Completed | Two Trabecular Micro-bypass Stents & Postoperative Travoprost to Treat Glaucoma Subjects on Two Hypotensive Ag Open-angle Glaucoma | Phase 4 | 2013-03-01 |
| Completed | Two Second-Generation Trabecular Micro-bypass Stents to Treat Glaucoma Subjects on One Hypotensive Medication Open Angle Glaucoma | Phase 4 | 2013-03-01 |
| Completed | Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus Keratoconus | Phase 3 | 2012-07-01 |
| Withdrawn | Safety and Efficacy Study for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Sur Corneal Ectasia | Phase 3 | 2012-07-01 |
| Completed | Safety and Efficacy Study of Corneal Collagen Cross-Linking in Eyes With Keratoconus Keratoconus | Phase 3 | 2012-07-01 |
| Completed | Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System Primary Open-angle Glaucoma | N/A | 2012-01-16 |
| Completed | One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects Primary Open Angle Glaucoma (POAG) | N/A | 2012-01-01 |
| Completed | Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery Primary Open-angle Glaucoma | N/A | 2011-12-22 |
| Completed | Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Sur Open-angle Glaucoma | Phase 4 | 2011-09-01 |
| Completed | Subjects With Open-angle Glaucoma, Pseudoexfoliative Glaucoma, or Ocular Hypertension Naïve to Medical and Sur Open-angle Glaucoma | Phase 4 | 2011-09-01 |
| Completed | Open-angle Glaucoma Subjects on One Topical Hypotensive Medication Randomized to Treatment With One or Two Tra Open-angle Glaucoma | N/A | 2011-09-01 |
| Completed | Open-Angle Glaucoma Subjects With One Prior Trabeculectomy Treated Concurrently With One Suprachoroidal Stent Open-Angle Glaucoma | N/A | 2011-09-01 |
| Completed | Open-angle Glaucoma Subjects on One Ocular Hypotensive Medication Randomized to Treatment With Two Trabecular Open-angle Glaucoma | N/A | 2011-09-01 |
| Completed | Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction o Primary Open Angle Glaucoma (POAG) | N/A | 2010-12-01 |
| Completed | Prospective Evaluation of Open-Angle Glaucoma Subjects on One Topical Hypotensive Medication Treated With Two Subjects With Primary Open-angle Glaucoma (POAG) | Phase 4 | 2010-12-01 |
| Completed | A Prospective Evaluation of Open-Angle Glaucoma Subjects on Two Topical Hypotensive Medications Treated With O Subject With Primary Open-angle Glaucoma (POAG) | Phase 4 | 2010-12-01 |
| Completed | Prospective Evaluation of Open-angle Glaucoma Subjects on Two Topical Hypotensive Medication Treated With Two Subjects With Primary Open-angle Glaucoma (POAG) | Phase 4 | 2010-12-01 |
| Completed | GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma Glaucoma | Phase 3 | 2010-01-01 |
| Completed | Feasibility Study of the Vedera KXS for Treatment of Keratoconus Keratoconus | N/A | 2010-01-01 |
| Completed | Clinical Evaluation of the Vedera KXS for the Treatment of Spherical Myopia Myopia | N/A | 2009-06-01 |
| Completed | Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (PO Eye Diseases, Glaucoma, Open-Angle, Glaucoma | Phase 4 | 2009-05-01 |
| Completed | A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle Glaucoma Glaucoma, Eye Diseases, Glaucoma, Open-Angle | Phase 4 | 2009-05-01 |
| Completed | Corneal Collagen Cross-linking for Progressive Keratoconus Progressive Keratoconus | Phase 3 | 2007-12-01 |
| Completed | Corneal Collagen Cross-Linking for Ectasia (CXL) Ectasia | Phase 3 | 2007-12-01 |
| Completed | Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract Open-angle Glaucoma | Phase 3 | 2007-03-01 |
| Completed | A Study of the Trabecular Micro-bypass Stent in Combination With Cataract Surgery in Subjects With Open Angle Open-Angle Glaucoma | Phase 3 | 2005-06-01 |
| Completed | A Study of the iStent in Combo With Cataract Surgery in Newly Diagnosed Open Angle Glaucoma or OH Patients. Open-Angle Glaucoma | N/A | 2005-02-01 |
| Unknown | A Study of the Glaukos Trabecular Micro-bypass Stent in Open Angle Glaucoma Subjects 1 Stent Versus 2 Open-Angle Glaucoma | Phase 4 | 2004-08-01 |
| Completed | A Study of the Glaukos Trabecular Micro-Bypass Stent in Refractory Open Angle Glaucoma Subjects Open-Angle Glaucoma | Phase 4 | 2003-04-01 |
| Completed | A Study of the Trabecular Micro-Bypass Stent in Combination With Cataract Surgery in Open Angle Glaucoma Subje Open-Angle Glaucoma | Phase 4 | 2003-04-01 |