NCT02754596

Study Comparing Travoprost Intraocular Implants to Timolol Ophthalmic Solution

Prospective, Randomized Phase II Study Comparing Two Elution Rates of Glaukos Travoprost Intraocular Implants to Timolol Maleate Ophthalmic Solution, USP 0.5%

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 154 (actual)
• Sponsor: Glaukos Corporation · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized trial comparing two elution doses of the Travoprost Intraocular implant to timolol ophthalmic solution.

Detailed description

This is a randomized trial comparing two elution doses of the Travoprost Intraocular implant to timolol ophthalmic solution in patients with open-angle glaucoma. Study assessments will include IOP and medication use as well as safety parameters.

Conditions

• Glaucoma Open-angle

Interventions

Type	Name	Description
DRUG	Travoprost Intraocular Implant, high elution	Surgical implant placed within the eye to elute travoprost.
DRUG	Travoprost Intraocular Implant, low elution	Surgical implant placed within the eye to elute travoprost
DRUG	Timolol Maleate Ophthalmic Solution, 0.5%	Instillation of one drop of timolol in the study eye twice daily

Timeline

• Start date: 2016-03-29
• Primary completion: 2017-08-01
• Completion: 2020-07-21
• First posted: 2016-04-28
• Last updated: 2023-09-26
• Results posted: 2023-08-09

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study