Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT01643252

Safety and Efficacy Study for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Surgery

A Multi-Center, Randomized, Placebo-Controlled Evaluation of the Safety and Efficacy of the KXL System With VibeX (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Surgery

Status
Withdrawn
Phase
Phase 3
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Glaukos Corporation · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

The objectives of this study are to evaluate the safety and efficacy of corneal collagen cross-linking performed with VibeX (riboflavin ophthalmic solution) and the KXL System as compared to placebo in impeding the progression of, and/or reducing, maximum corneal curvature.

Detailed description

The objectives of this study are to evaluate the safety and efficacy of corneal collagen cross-linking performed with VibeX (riboflavin ophthalmic solution) and the KXL System as compared to placebo in impeding the progression of, and/or reducing, maximum corneal curvature.

Conditions

Interventions

TypeNameDescription
DRUGriboflavin: 0.12% riboflavin ophthalmic solution with the KXL systemSubjects will receive 0.12% riboflavin ophthalmic solution (VibeX) followed by irradiation with the KXL system at 30mW/cm\^2 for 4 minutes
DRUGplacebo: 0.0% riboflavin ophthalmic solution with the KXL systemSubjects will receive 0.0% riboflavin ophthalmic solution (placebo) followed by irradiation with the KXL system at 30mW/cm\^2 for 4 minutes

Timeline

Start date
2012-07-01
First posted
2012-07-18
Last updated
2021-04-26

Source: ClinicalTrials.gov record NCT01643252. Inclusion in this directory is not an endorsement.