Clinical Trials Directory

Trials / Sponsors / Massachusetts Eye and Ear Infirmary

Massachusetts Eye and Ear Infirmary

Academic / Other · 98 registered clinical trials23 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingSubconjunctival Humira for Boston Keratoprosthesis
Penetrating Keratoplasty, Multiple Graft Failure, Ocular Cicatricial Pemphigoid
Phase 12026-06-01
Not Yet RecruitingThe Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy
Proliferative Vitreoretinopathy, Proliferative Vitreo-Retinopathy, Rhegmatogenous Retinal Detachment
Phase 12026-04-01
Not Yet RecruitingLactiplantibacillus Plantarum 299v Probiotic Supplementation in Patients With Diabetic Macular Edema
Diabetic Macular Edema
Phase 22026-03-01
RecruitingTesting Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait
Vestibular Disorder, Aging
N/A2026-02-25
WithdrawnAssessment of Corneal Endothelial Function Following Hypoxic Stress
Fuchs' Endothelial Corneal Dystrophy
Phase 1 / Phase 22025-12-01
RecruitingThe Glaucoma and Retinopathy Screening Study
Glaucoma
N/A2025-07-16
RecruitingExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty
Corneal Transplant Failure
Phase 22025-04-01
RecruitingctDNA in Cutaneous Squamous Cell Carcinoma
Cutaneous Squamous Cell Carcinoma
2025-03-24
RecruitingA Trial of Hydrus Microstent Versus Goniotomy
Glaucoma, Glaucoma, Open-Angle
N/A2025-02-14
RecruitingMeasurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment
Squamous Cell Carcinoma of Head and Neck
2025-02-03
RecruitingTopical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment
Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy
Phase 1 / Phase 22025-01-14
TerminatedSimulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision
One Eye Blindness, Blind Left Eye, Blind Right Eye
N/A2024-08-04
RecruitingReminder-cue Scanning Training for Homonymous Visual Field Loss
Homonymous Hemianopia, Homonymous Quadrantanopia
N/A2024-05-14
Active Not RecruitingAssessing the Utility of Plasma ctHPVDNA for Anal Cancer Screening
Anal Dysplasia
2024-04-03
TerminatedLatanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension
Glaucoma, Ocular Hypertension
Phase 12024-04-03
RecruitingImproving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mappin
Deafness, Cochlear Hearing Loss
N/A2024-02-27
CompletedMultiplexing Prism Fitting for Field Expansion of Monocular Vision
One Eye Blindness, Blind Left Eye, Blind Right Eye
N/A2023-12-27
RecruitingCharacterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
2022-11-07
Active Not RecruitingClinical Trial of Multi-Periscopic Prism Glasses for Hemianopia
Homonymous Hemianopia
N/A2022-10-03
WithdrawnClosed-loop Rehabilitation for Hyperactive Hearing
Tinnitus, Hyperacusis
N/A2022-09-21
Active Not RecruitingDoxycycline in Cutaneous Schwannoma (NF2)
Neurofibromatosis Type 2
Phase 1 / Phase 22022-09-19
RecruitingPerceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
Deafness
N/A2022-09-16
RecruitingDropless Pars Plana Vitrectomy Study
Rhegmatogenous Retinal Detachment
Phase 42022-07-25
RecruitingDeep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
N/A2022-06-21
RecruitingClinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
Dystonia, Drug Induced Dystonia, Parkinson Disease
N/A2022-06-01
Active Not RecruitingFeasibility Test of Virtual Reality Obstacle Detection for Low Vision Walking
Hemianopsia, Homonymous Hemianopia, Tunnel Vision
N/A2022-05-17
RecruitingUnderstanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
EARLY_Phase 12022-03-24
WithdrawnOptiflow vs. Convential Anesthesia During Pediatric Laryngeal Papilloma Removal
Laryngeal Papilloma, Recurrent
Phase 1 / Phase 22022-02-01
WithdrawnTracking Biomarkers of Speech Intelligibility
High-Frequency Hearing Loss
N/A2022-01-01
UnknownMeibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necro
Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses, Ocular Surface Disease
N/A2021-12-01
CompletedUnderstanding Visual Confusion Using Stereoscopic Displays
Diplopia, Binocular Vision Suppression, Binocular; Fusion, With Defective Stereopsis
N/A2021-11-09
WithdrawnEvaluation of Dextenza in Patients With Ocular GVHD and Effects on Ocular Surface Disease Outcomes
Graft Vs Host Disease
Phase 42021-09-01
CompletedFLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial
Trachomatous Trichiasis (TT), Eye Diseases, Eyelid Diseases
Phase 32021-08-19
CompletedClinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis
Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis
N/A2021-06-01
CompletedNetarsudil Use After Descemtorhexis Without Endothelial Keratoplasty
Fuchs' Endothelial Dystrophy
EARLY_Phase 12021-03-28
RecruitingTherapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema
Cystoid Macular Edema
Phase 1 / Phase 22021-03-15
Active Not RecruitingLenvatinib in Locally Advanced Invasive Thyroid Cancer
Differentiated Thyroid Cancer, Advanced Cancer
Phase 22021-03-09
RecruitingDark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD
Age-related Macular Degeneration
Phase 22021-02-04
RecruitingFeasibility Tests for Various Prism Configurations for Visual Field Loss
Hemianopia, Homonymous, Tunnel Vision, Visual Field Defect, Peripheral
N/A2020-11-06
CompletedAnti-VEGF Therapy for Acute Thyroid Eye Disease
Thyroid Eye Disease
Phase 22020-11-02
RecruitingTargeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
Fuchs Endothelial Corneal Dystrophy
Phase 22020-09-16
CompletedctDNA Liquid Biopsy for Early Assessment of Residual Disease in HPV-associated Head and Neck Cancer (Clear-HPV
HPV Positive Oropharyngeal Squamous Cell Carcinoma
2020-08-01
UnknownVestibular Precision: Physiology & Pathophysiology
Vestibular Schwannoma, Inner Ear Disease, Dizziness
N/A2020-07-01
CompletedA Comparison of the Effect of Suture Material on Blepharoplasty Incision
Dermatochalasis, Ptosis, Eyelid
N/A2020-05-30
WithdrawnAnalysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma
Migraine, Vestibular Migraine, Vestibular Schwannoma
N/A2019-09-05
WithdrawnVestibular Implants Tested in Human Subjects
Vestibular Disorder, Vestibular Ataxia, Vestibular Loss, Bilateral
N/A2019-08-01
CompletedClinical Trial to Improve the Magnetic Levator Prosthesis
Blepharoptosis, Ptosis, Eyelid, Myasthenia Gravis
N/A2019-02-07
UnknownPilocarpine and Brimonidine in Patients With Monofocal Lenses
Presbyopia, Pseudophakia
EARLY_Phase 12019-01-21
Withdrawn4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular Migraine
Vestibular Migraine, Migraine Disorders, Vestibular Diseases
Phase 22019-01-01
CompletedNetarsudil Use After Descemetorhexis Without Endothelial Keratoplasty
Fuchs' Endothelial Dystrophy, Cataract
EARLY_Phase 12018-10-02
WithdrawnPostoperative Ibuprofen Use and Risk of Bleeding in Pediatric Tonsillectomy
Tonsillectomy With or Without Adenoidectomy
Phase 12018-09-01
Active Not RecruitingStudy of Aspirin in Patients With Vestibular Schwannoma
Vestibular Schwannoma, Acoustic Neuroma, Neurofibromatosis 2
Phase 22018-06-11
UnknownAcetaminophen Given Per Os and Intravenous in Sinus Surgery
Acetaminophen
Phase 32018-03-28
CompletedMobile Medical Application for Cost-effective Strabismus Screening
Strabismus
2018-02-01
CompletedCollision Warning Device for Blind and Visually Impaired
Hemianopia, Hemianopsia, Peripheral Visual Field Defect
N/A2018-01-22
UnknownMotion Perception in Individuals With Type 2 Diabetes
Diabetes Mellitus, Type 2
2017-08-01
CompletedPerioperative Complications of Deep Extubation in Adults
Anesthesia Complication
2017-05-01
CompletedMucinex® for Treatment of Filamentary Keratitis
Filamentary Keratitis
N/A2016-09-01
Completed5-fluorouracil Versus Placebo in Periocular Full Thickness Skin Grafts
Ectropion, Skin Neoplasms
Phase 22016-08-25
CompletedLimbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft
Limbal Stem Cell Deficiency
Phase 1 / Phase 22016-08-01
TerminatedExploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Me
Vestibular Schwannoma, Meningioma, Acoustic Neuroma
EARLY_Phase 12015-12-01
RecruitingBrain Networks in Dystonia
Spasmodic Dysphonia, Singer's Dystonia, Writer's Cramp
2015-08-01
CompletedComputer-Based Auditory Rehabilitation
Presbycusis
N/A2015-04-01
TerminatedThe Effect of Dexmedetomidine on Airway Complications After Deep or Awake Extubation
Adenotonsillar Hypertrophy, Obstructive Sleep Apnea, Tonsillitis
Phase 42015-03-01
CompletedUse of Amplification in Children With Unilateral Hearing Loss
Unilateral Hearing Loss
N/A2014-10-01
CompletedSafety and Efficacy of Topical Tacrolimus 0.05% in the Treatment of Ocular Graft-Versus-Host Disease
Ocular GVHD
Phase 12013-12-01
TerminatedAuditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects
Bilateral Hearing Loss for Causes Other Than Tumors
N/A2013-05-01
CompletedProphylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Control
Sinusitis
Phase 42013-02-01
CompletedBinocular Treatment of Amblyopia Before and After Strabismus Surgery
Amblyopia, Strabismus
N/A2013-01-01
TerminatedAuditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects
Bilateral Hearing Loss for Causes Other Than Tumors
N/A2012-11-01
WithdrawnPrevalence of Dyschromatopsia in Glaucoma Patients
Open Angle Glaucoma
2012-11-01
CompletedPostoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Tonsillectomy, Adenoidectomy
Phase 22012-05-03
TerminatedIn Vivo Confocal Microscopy Study of Pigmented Conjunctival Lesions
Nevus, Racial Melanosis, Primary Acquired Melanosis
2011-09-01
CompletedEfficacy of Zylet vs. Lotemax for the Treatment of Ocular Surface Inflammation/MGD/Blepharitis
Meibomian Gland Dysfunction, Posterior Blepharitis
Phase 42011-08-01
CompletedStudy to Evaluate the Efficacy of Optical Imaging to Evaluate the Anatomy of the Developing Pediatric Vocal Fo
Vocal Fold Development
2011-07-01
TerminatedEffects of Anti-Glaucoma Medications on the Ocular Surface
Glaucoma
Phase 42011-02-01
CompletedRandomized Controlled Trial of Voice on Children With Vocal Nodules
Vocal Fold Nodules
2011-01-01
WithdrawnInfliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Tox
Stevens-Johnson Syndrome, Corneal Blindness
Phase 1 / Phase 22010-12-01
CompletedThe Effects of Caffeinated Coffee on Intraocular Pressure
Primary Open Angle Glaucoma
N/A2010-11-01
CompletedComparison of Four Different Aberrometers for Evaluation of Higher Order Visual Aberrations
Normal Individuals With Visual Aberrations
2010-08-01
CompletedEffect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface
Myopia, Refractive Error
Phase 42010-08-01
WithdrawnIntravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD
Choroidal Neovascularization, Myopia, Punctate Inner Choroidopathy (PIC)
N/A2010-08-01
CompletedEvaluating Perioperative Dexamethasone and the Risk of Bleeding in Tonsillectomy
Post-operative Hemorrhage
N/A2010-07-01
CompletedEffect of Alphagan on Retinal Blood Flow Autoregulation and Motion Detection in Patients With Normal Pressure
Glaucoma
N/A2010-03-01
WithdrawnPropranolol Administration in Pediatric Patients With Recurrent Respiratory Papillomatosis
Recurrent Respiratory Papillomatosis
Phase 2 / Phase 32010-01-01
CompletedPEMF: an Adjunct Therapy for Anterior Uveitis
Anterior Uveitis, Iritis
N/A2009-08-01
WithdrawnTopical Microporous Polysaccharide Hemospheres Versus Electrocautery for Control of Pediatric Post-Tonsillecto
Obstructive Sleep Disorder, Obstructive Sleep Apnea, Tonsillar Hypertrophy
Phase 32009-07-01
CompletedEffect of Cosopt Versus Combigan on Retinal Vascular Autoregulation in Primary Open Angle Glaucoma (POAG)
Glaucoma
N/A2009-01-01
WithdrawnSomatosensory Based Treatments for Tinnitus
Tinnitus
N/A2008-12-01
CompletedRanibizumab in Combination With Proton Beam Irradiation for Choroidal Melanoma
Choroidal Melanoma
Phase 12008-06-01
CompletedIntraoperative Laryngeal Electromyography (LEMG) in Children With Vocal Fold Immobility: a Longitudinal Study
Vocal Fold Immobility
2008-01-01
TerminatedThe Prophylactic Use of Topical Cyclosporine A 0.05% to Prevent Graft Versus Host Disease Related Dry Eye
Dry Eye
Phase 42007-08-01
WithdrawnUse of Self-management Group to Improve Quality of Life in Patients With Low Vision
Age Related Macular Degeneration
N/A2007-05-01
CompletedTopical Avastin for Treatment of Corneal Neovascularization
Corneal Neovascularization
Phase 12007-02-01
CompletedMulti-Center, Randomized Trial of the Pulsed Dye Laser for JORRP
Recurrent Respiratory Papillomatosis
2007-01-01
WithdrawnLongitudinal Study of Children With a Chronic Cough and the Impact of Gastroesophageal Reflux
Cough, Gastroesophageal Reflux
Phase 32006-01-01
CompletedSudden Deafness Treatment Trial
Sudden Deafness
Phase 32004-12-01
No Longer AvailableCompassionate Use Arm - ABI541 ABI for 10 NF2 Patients
Neurofibromatosis Type 2, Severe Profound Sensorineural Hearing Loss