NCT01364207

The Effects of Caffeinated Coffee on Intraocular Pressure

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: Massachusetts Eye and Ear Infirmary · Academic / Other
• Sex: All
• Age: 40 Years – 89 Years
• Healthy volunteers: Accepted

Summary

High intraocular pressure (IOP) is a known risk factor for developing primary open-angle glaucoma (POAG). There is controversy in the literature regarding the degree to which caffeine influences IOP, with some studies reporting minimal changes in IOP while others report up to 4 mmHg increases. To date there are no double-masked randomized controlled trials that examine acute caffeinated coffee's effects on IOP in patients with or at risk for primary open-angle glaucoma. The investigators aim to better understand the relationship between acute caffeinated coffee (vs decaffeinate coffee) consumption and IOP in a double-masked, crossover randomized controlled clinical trial.

Conditions

• Primary Open Angle Glaucoma

Interventions

Type	Name	Description
OTHER	Caffeinated Coffee	Participants will drink one 8 oz cup in the morning hours. Participants have 15 minutes to drink the coffee but may do so in less time.
OTHER	Decaffeinated Coffee	Participants will drink one 8 oz cup in the morning hours. Participants have 15 minutes to drink the coffee but may do so in less time.

Timeline

• Start date: 2010-11-01
• Primary completion: 2011-08-01
• Completion: 2012-06-01
• First posted: 2011-06-02
• Last updated: 2012-10-31
• Results posted: 2012-10-31

Locations

1 site across 1 country: United States