| Not Yet Recruiting | PRESERFLO™ MicroShunt XI Observational PMCF Study With no Control Group NCT07235592 | Santen SAS | — |
| Recruiting | DSLT for Reducing Medication in Glaucoma NCT07390890 | The Eye Institute of West Florida | — |
| Recruiting | Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea NCT07447011 | Cairo University | N/A |
| Recruiting | OMNI 3.1 Surgical System in Subjects With Primary Open-Angle Glaucoma NCT06991270 | Sight Sciences, Inc. | N/A |
| Recruiting | Clinical Study Evaluating the Safety and Performance of the MIST Device for Intraocular Pressure Reduction in NCT07358650 | Hexiris Inc | N/A |
| Not Yet Recruiting | Rocklatan Adds Pressure Reduction After MIGS (Minimally Invasive Glaucoma Surgery) NCT07048886 | Center for Sight Las Vegas | Phase 4 |
| Recruiting | A Study of the Helix Surgical System in Primary Open-Angle Glaucoma (POAG) and Cataract (HELIX) NCT06948773 | Sight Sciences, Inc. | N/A |
| Recruiting | Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glau NCT06682962 | Okuvision GmbH | N/A |
| Recruiting | A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab E NCT06822738 | AbbVie | Phase 3 |
| Recruiting | Effects of Primary Open-angle Glaucoma on Visual-motor Coordination NCT06692205 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Not Yet Recruiting | The Objective is to Evaluate the Anterior Chamber Angle After BANG Procedure, the Study Will Recruit 12 Patien NCT06526416 | Benha University | — |
| Terminated | A Clinical Trial Comparing the OMNI Surgical System to Standard Medical Treatment in Patients With Primary Ope NCT06407973 | Sight Sciences, Inc. | Phase 4 |
| Recruiting | CRISPR/Cas9 Instantaneous Gene Editing Therapy to Intraocular Hypertensive POAG With MYOC Mutation NCT06465537 | Shanghai BDgene Co., Ltd. | N/A |
| Recruiting | Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Ope NCT06313749 | Sanoculis Ltd | N/A |
| Recruiting | Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population NCT05902871 | BelkinVision | N/A |
| Unknown | A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TF NCT06177678 | Kukje Pharma | Phase 2 |
| Recruiting | XEN Glaucoma Gel Stent Versus Trabeculectomy NCT05439161 | Prof. Dr. Herbert Reitsamer | N/A |
| Recruiting | A Study of AMDX-2011P in Participants With Primary Open Angle Glaucoma NCT06223048 | Amydis Inc. | Phase 2 |
| Completed | Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Ey NCT06144918 | Skye Bioscience, Inc. | Phase 2 |
| Enrolling By Invitation | Uddevalla Skövde Transscleral Micropulse Study NCT05557721 | Vastra Gotaland Region | — |
| Unknown | Impact of Home Intraocular Pressure Telemonitoring on Intraocular Pressure Control and Glaucoma Progression NCT05940623 | The University of Hong Kong | N/A |
| Completed | Regulation of Intraocular Pressure in Glaucoma Patients by Acupressure NCT05898997 | National Taiwan University Hospital | N/A |
| Unknown | Electroretinogram and Retinal Vascular Changes After Cataract Surgery NCT05871034 | Sohag University | N/A |
| Recruiting | Multicenter Glaucoma Study Investigating Standalone Canaloplasty NCT05786196 | Nova Eye, Inc. | N/A |
| Active Not Recruiting | Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study NCT05695027 | Columbia University | Phase 2 / Phase 3 |
| Terminated | Safety and Tolerability of a Timolol Releasing Intraocular Implant in Subjects With Primary Open-angle Glaucom NCT06321562 | EyeD Pharma | Phase 1 |
| Enrolling By Invitation | MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract NCT05432245 | iSTAR Medical | N/A |
| Unknown | Visco-Circumferential-Suture-Trabeculotomy Versus Rigid Probe Viscotrabeculotomy in Primary Open Angle Glaucom NCT05666440 | Mansoura University | N/A |
| Unknown | Alternate Nostril Breathing Training in Geriatrics With Glaucoma and High Blood Pressure NCT05605743 | Cairo University | N/A |
| Active Not Recruiting | GORE Glaucoma Drainage Implant Clinical Study Dominican Republic NCT05557058 | W.L.Gore & Associates | N/A |
| Recruiting | Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients Wit NCT05564091 | Nova Eye, Inc. | N/A |
| Unknown | Microinvasive Glaucoma Surgery -The Lowering Effect of Intraocular Pressure on Glaucoma Patients With High Fre NCT05466526 | National Taiwan University Hospital Hsin-Chu Branch | N/A |
| Unknown | Retinal Vascular Changes in Primary Open Angle Glaucoma Patients NCT05351307 | Sohag University | — |
| Recruiting | Assessment of Endothelial Glycocalyx in Patients With Primary Open-angle Glaucoma NCT05264818 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Recruiting | Nanodropper Use in Primary Open-Angle Glaucoma Patients: A Non-Inferiority Trial NCT05844384 | 59th Medical Wing | N/A |
| Completed | GlaucoT Glaucoma Treatment Glasses in the Treatment of Primary Open-Angle Glaucoma NCT05253534 | Glaucot Teknoloji Anonim Sirketi | N/A |
| Completed | Effect of Acupuncture on Visual Acuity and Visual Field in Patients With Primary Open-angle Glaucoma NCT05247762 | China Medical University Hospital | N/A |
| Unknown | Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isop NCT05279716 | Santen Pharmaceutical Asia Pte. Ltd. | Phase 4 |
| Active Not Recruiting | Multimodal Morpho-functional Study in Glaucoma Patients-Citicoline Oral Solution NCT05315206 | Fondazione G.B. Bietti, IRCCS | N/A |
| Completed | Visual Field Changes and OCT Angiographic Chorioretinal Changes in Patients With Primary Open Angle Glaucoma NCT06978101 | Assiut University | — |
| Completed | A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension NCT05022004 | Sun Pharmaceutical Industries Limited | Phase 3 |
| Terminated | Safety and Effectiveness of the Hydrus Microstent NCT05198297 | Alcon Research | N/A |
| Unknown | A Study of Efficacy and Safety of PHP-201 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension NCT04863365 | pH Pharma | Phase 3 |
| Completed | Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glau NCT04828057 | Santen Pharmaceutical (Taiwan) Co., LTD | — |
| Terminated | Development and Validation of a Model to Predict Fast Progression in Glaucoma NCT04454190 | Duke University | — |
| Terminated | Multicenter Ab-interno Glaucoma Study Investigating Canaloplasty NCT04769453 | Nova Eye, Inc. | N/A |
| Completed | Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma o NCT04830397 | Qlaris Bio, Inc. | Phase 2 |
| Unknown | Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD NCT04891588 | Klinički Bolnički Centar Zagreb | N/A |
| Completed | BREMEN Eye Drops Versus Combigan for Open-angle Glaucoma or Intraocular Hypertension NCT03235232 | EMS | Phase 3 |
| Terminated | Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetin NCT04784234 | Wills Eye | N/A |
| Completed | Study of LL-BMT1 in Patients With Elevated Intraocular Pressure NCT04747808 | MediPrint Ophthalmics, Inc. | Phase 2 |
| Completed | Additional Long-Term Follow-up for Subjects Implanted With a CyPass® Micro-Stent NCT04629521 | Alcon Research | N/A |
| Completed | Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol NCT04742283 | Santen Inc. | Phase 2 |
| Completed | Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate NCT04620135 | Aerie Pharmaceuticals | Phase 3 |
| Unknown | Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients NCT04609345 | Santen Pharma Malaysia Sdn Bhd | — |
| Unknown | Glaucoma Screening Using Dynamic Analysis of Computerized Pupillary Light Reflex Assessment Device NCT04595227 | Peking University | — |
| Unknown | Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary Glaucoma NCT04736264 | Universiti Sains Malaysia | N/A |
| Recruiting | Hydrus® Microstent New Enrollment Post-Approval Study NCT04553523 | Alcon Research | N/A |
| Unknown | Cyclophotocoagulation in Primary Open Angle Glaucoma NCT04430296 | Cairo University | N/A |
| Unknown | Intraocular Pressure After Preserflo / Innfocus Microshunt Implantation vs Trabeculectomy NCT04440527 | Medical University Innsbruck | N/A |
| Completed | Safety and Effectiveness of VISULAS Green Selective Laser Trabeculoplasty (SLT) NCT04519814 | Carl Zeiss Meditec AG | N/A |
| Unknown | A Clinical Study to Evaluate the Efficacy and Safety of CKD-351 NCT04448223 | Chong Kun Dang Pharmaceutical | Phase 2 |
| Completed | Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latano NCT04405245 | EyePoint Pharmaceuticals, Inc. | Phase 2 |
| Completed | PRESERFLO® MicroShunt Extension Study NCT04333433 | InnFocus Inc. | — |
| Unknown | SIGHT Study: Cost-effectiveness of InnFocus Microshunt Implantation vs. Trabeculectomy. NCT03931564 | Maastricht University Medical Center | N/A |
| Withdrawn | IOP and Medication Reduction in MIGS Procedures NCT04202510 | Wills Eye | N/A |
| Unknown | Effect of Metformin on Visual Function in Patients With Glaucoma NCT04155164 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Terminated | Effect of Xen Implantation on the Aqueous Humor Proteome NCT04141865 | Price Vision Group | — |
| Unknown | Decorin in Sub Scleral Trabeculectomy NCT03924544 | Cairo University | Phase 1 |
| Completed | Comparison Between Latanoprost , Travoprost and Tafluprost in Reducing IOP Fluctuation in POAG Patients NCT04461249 | Kasr El Aini Hospital | — |
| Recruiting | Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults NCT04396002 | University of Alabama at Birmingham | — |
| Completed | Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AKB-9778 Ophthalmic Solut NCT04284514 | Aerpio Therapeutics | Phase 1 |
| Completed | Tafluprost Preservative Free Switch Study NCT04654611 | Tun Hussein Onn National Eye Hospital | Phase 4 |
| Completed | Levobetaxolol Hydrochloride Eye Drops for Treatment of Primary Open-angle Glaucoma or Ocular Hypertension NCT02617459 | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Phase 3 |
| Unknown | Efficacy and Safety of Latanoprost/Timolol for Primary Open Angle Glaucoma NCT04098861 | Universiti Kebangsaan Malaysia Medical Centre | Phase 4 |
| Unknown | A Clinical Study to Evaluate the Efficacy and Safety of CKD-351 NCT03762369 | Chong Kun Dang Pharmaceutical | Phase 3 |
| Recruiting | Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study NCT03921931 | Medical University of Vienna | N/A |
| Completed | Optical Coherence Tomography of Nerve Fiber Layer and Ganglion Cell Complex After Cataract Extraction NCT03889652 | Kasr El Aini Hospital | — |
| Active Not Recruiting | Impact of Glaucoma and Visual Field Loss on Life Space NCT03673644 | University of Alabama at Birmingham | — |
| Completed | Long-term Safety and Performance of the ARGOS-IO Intraocular Pressure Sensor System in Subjects With Primary O NCT03651336 | Implandata Ophthalmic Products GmbH | N/A |
| Completed | Modified Trabeculectomy With an ESST Versus Conventional SST for Management of Primary Open Angle Glaucoma NCT03480711 | Rehab mahmoud abdelhamid mohamed | N/A |
| Terminated | PRO-122 Versus Concomitant Therapy in Subjects With Uncontrolled Primary Open-angle Glaucoma (PRO-122LATAM) NCT03193333 | Laboratorios Sophia S.A de C.V. | Phase 3 |
| Completed | Educational Intervention to Adopt SLT as First-Line Glaucoma Treatment NCT03365778 | Wills Eye | N/A |
| Terminated | Post Approval Study of the CyPass System NCT03273907 | Alcon Research | N/A |
| Completed | Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study NCT03323164 | Wills Eye | Phase 4 |
| Terminated | Assessing Ocular Hemodynamic Response to Surgical Intervention in Glaucoma NCT02891317 | University of North Carolina, Chapel Hill | — |
| Completed | PAIR Study-PAP And IOP Relationship: Study 2 NCT03145129 | Papworth Hospital NHS Foundation Trust | — |
| Terminated | PAIR Study-PAP And IOP Relationship: Study 1 NCT03127813 | Papworth Hospital NHS Foundation Trust | N/A |
| Unknown | Metabolomics in Surgical Ophthalmological Patients NCT03098316 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Efficacy and Tolerability of an Innovative Formulation of BAK-free Latanoprost NCT03331770 | Laboratorios Poen | Phase 4 |
| Completed | The Effects of Visior on Ocular Hemodynamics NCT02959593 | Visior Technologies Ltd. | N/A |
| Completed | Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma NCT03483402 | University Hospital of Patras | N/A |
| Completed | Advanced Glycation End Products as a Biomarker for Accelerated Ageing NCT02863224 | University of Plymouth | — |
| Unknown | Surgical Approaches in Treating Uncontrolled Glaucoma in Black African and African-Caribbeans NCT02989207 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Completed | Ahmed Glaucoma Valve Surgery With Mitomycin-C NCT02805257 | University of California, San Francisco | Phase 2 |
| Completed | A Multi-center, Randomized, Blinded Evaluator, Active Control, Parallel, Phase III Study to Evaluate the Effic NCT03419975 | Taejoon Pharmaceutical Co., Ltd. | Phase 3 |
| Completed | Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFOR NCT03257813 | Laboratorios Sophia S.A de C.V. | Phase 3 |
| Completed | InnFocus MicroShunt Versus Trabeculectomy Study NCT01881425 | InnFocus Inc. | N/A |
| Completed | A Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution in Subjects With Primary Open Angle Gl NCT02623738 | Santen Pharmaceutical Co., Ltd. | Phase 2 / Phase 3 |
| Terminated | Assessment of Optic Nerve Radiation in Patients With Glaucoma and Ocular Hypertension by 7 Tesla Diffusion Ten NCT01864317 | Medical University of Vienna | Phase 2 |
| Unknown | A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucoma NCT02792803 | Dr. David Yan | Phase 4 |
| Terminated | Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension NCT02801617 | Laboratorios Sophia S.A de C.V. | Phase 3 |
| Completed | An Open-label Extension Study to Evaluate the Safety of the 13 mg Bimatoprost Ocular Insert NCT02537015 | ForSight Vision5, Inc. | Phase 2 |
| Unknown | Effect of Ginkgo Biloba Capsule on Visual Function of Primary Open-angle Glaucoma With Blood Stasis Syndrome NCT04334564 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Phase I Dose Escalation Study to Investigate the Safety of ISTH0036 in Subjects With Glaucoma Undergoing Trabe NCT02406833 | Isarna Therapeutics GmbH | Phase 1 |
| Completed | Reproducibility of RNFL and ONH Measurements in OAG With Heidelberg Spectralis SD-OCT Glaucoma Module Premium NCT02247284 | University of Zurich | N/A |
| Completed | Minimally Invasive Micro Sclerostomy First in Man Safety and Preliminary Performance Study NCT02355990 | Sanoculis Ltd | N/A |
| Completed | Dose-Ranging Study of the Bimatoprost Ocular Insert NCT02358369 | ForSight Vision5, Inc. | Phase 2 |
| Terminated | Multicenter Investigation of Trabecular Micro-Bypass Stents vs. Laser Trabeculoplasty NCT02327312 | Glaukos Corporation | N/A |
| Unknown | Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. NCT02300818 | American Society Of Thermalism And Climatology Inc | Phase 1 / Phase 2 |
| Completed | An Open-Label Extension Study to Evaluate the Safety of the ForSight VISION5 Product NCT02143843 | ForSight Vision5, Inc. | Phase 2 |
| Unknown | Effectiveness and Safety of Adipose-Derived Regenerative Cells for Treatment of Glaucomatous Neurodegeneration NCT02144103 | Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation | Phase 1 / Phase 2 |
| Completed | Post Market Study of the InnFocus MicroShunt NCT02177123 | InnFocus Inc. | N/A |
| Completed | The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS NCT02016898 | Duke University | Phase 2 |
| Terminated | Imaging Lens Deposits in Exfoliation Syndrome NCT02042703 | Duke University | — |
| Completed | Safety and Efficacy of T-2345 Compared to Xalatan in Subjects With Primary Open Angle Glaucoma or Ocular Hyper NCT02059278 | Nephron Pharmaceuticals Corporation | Phase 3 |
| Terminated | Efficacy of the Brand-name Latanoprost and One of Its Generic Version in Primary Open Angle Glaucoma and Ocula NCT02047630 | CHU de Quebec-Universite Laval | Phase 4 |
| Completed | Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma. NCT02330978 | University of Sao Paulo | Phase 1 |
| Completed | Evaluation of the XEN Implant in Moderate Primary Open Angle Glaucoma (POAG) Participants NCT02006693 | AqueSys, Inc. | Phase 4 |
| Completed | Safety and Efficacy Assessment of Monoprost® in Comparison With Lumigan® 0.01 % and Lumigan® 0.03% Unit Dose NCT02017327 | Laboratoires Thea | Phase 4 |
| Completed | Bimatoprost Ocular Insert Compared to Topical Timolol Solution in Patients With Glaucoma or Ocular Hypertensio NCT01915940 | ForSight Vision5, Inc. | Phase 2 |
| Completed | An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in NCT01979913 | Dr. Anton Hommer | Phase 4 |
| Completed | A Study of the VISION5 Product in Patients With Glaucoma or Ocular Hypertension NCT01943721 | ForSight Vision5, Inc. | Phase 1 |
| Completed | Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction With Cataract Surgery Postmarket Registry NCT01841437 | Glaukos Corporation | — |
| Completed | The Effects of an Antioxidant Formulation on Ocular Blood Flow NCT01930487 | ScienceBased Health | N/A |
| Completed | Combined Viscocanalostomy, Phacoemulsification, OIogen Implant in Open Angle Glaucoma NCT03782051 | Zagazig University | N/A |
| Completed | Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inad NCT01896180 | Alleanza Pharmaceuticals, Inc. | Phase 2 |
| Completed | Post-approval Study of The Glaukos® iStent® Trabecular Micro-bypass Stent: Extended Follow-up of the Premarket NCT01836042 | Glaukos Corporation | — |
| Unknown | Multicenter Post-Approval Study Of The Glaukos® iStent® Trabecular Micro-Bypass Stent System In Conjunction Wi NCT01841450 | Glaukos Corporation | N/A |
| Completed | Associations of Vitamin D Deficiency and Vitamin D Receptor Polymorphisms With the Risk of Primary Open-angle NCT02539745 | Lv Yingjuan | — |
| Completed | Associations of Vitamin D Receptor ApaI and Tru9I Polymorphisms With the Risk of Primary Open-angle Glaucoma NCT02805231 | Lv Yingjuan | — |
| Completed | Comparison of Vitamin D Status and Vitamin D Receptor Polymorphisms in Patients With High Myopia and Primary O NCT03021629 | Lv Yingjuan | — |
| Completed | Efficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma Patients NCT03104621 | Gangnam Severance Hospital | Phase 4 |
| Completed | Structure Function Correlation in Primary Open Angle Glaucoma NCT02028572 | Vasan Eye Care Hospital | — |
| Unknown | Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle Glaucoma NCT01795014 | Universitaire Ziekenhuizen KU Leuven | — |
| Withdrawn | IOP Fluctuations in Primary Open Angle Glaucoma Patients Before and After Deep Sclerectomy NCT01766947 | Sensimed AG | N/A |
| Completed | IOP Fluctuations in Patients With Primary Open-angle Glaucoma, Before and After Selective Laser Trabeculoplast NCT01767753 | Sensimed AG | N/A |
| Completed | Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle Glaucoma NCT01711177 | Université de Montréal | N/A |
| Completed | Relationship Between 24-hour IOP Pattern and the 24-hour Blood Pressure Pattern in Patients With POAG NCT01769521 | Sensimed AG | N/A |
| Completed | Comparing Effectiveness of the Hydrus Microstent (TM) to Two iStents to Lower IOP in Phakic Eyes NCT02023242 | Ivantis, Inc. | N/A |
| Completed | Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension NCT03395535 | Moorfields Eye Hospital NHS Foundation Trust | Phase 4 |
| Completed | ATS907 Ph2a Open-Label Dose-ranging Safety and Tolerability in Primary Open Angle Glaucoma (POAG) and Ocular H NCT01668524 | Altheos, Inc. | Phase 2 |
| Active Not Recruiting | Advanced Glaucoma Progression Study NCT01742819 | University of California, Los Angeles | — |
| Terminated | IOP Fluctuations in Primary Open Angle Glaucoma Patients Before and After Deep Sclerectomy With Collagen Impla NCT01561001 | Sensimed AG | N/A |
| Completed | IOP Fluctuations in Patients With Sleep Apnea With or Without Primary Open Angle Glaucoma Using Positive Airwa NCT01560975 | Sensimed AG | N/A |
| Completed | Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucom NCT01528111 | Lexicon Pharmaceuticals | Phase 1 / Phase 2 |
| Completed | Multicentric Observational Study on Quality of Life in Glaucoma NCT01742104 | Mario Negri Institute for Pharmacological Research | — |
| Completed | Multicenter Study Using Glaukos® Trabecular Micro-Bypass Stent Model GTS400 Using the G2-M-IS Injector System NCT01461291 | Glaukos Corporation | N/A |
| Unknown | Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hype NCT01520116 | Altheos, Inc. | Phase 1 / Phase 2 |
| Completed | Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Catarac NCT01539239 | Ivantis, Inc. | N/A |
| Completed | Multicenter Investigation of the Glaukos® Suprachoroidal Stent Model G3 In Conjunction With Cataract Surgery NCT01461278 | Glaukos Corporation | N/A |
| Completed | Changes in Ocular Rigidity After Trabeculectomy in Patients With POAG NCT02544646 | Medical University of Vienna | N/A |
| Completed | Safety/Efficacy Study: OPA-6566 Ophthalmic Solution in Subjects With Primary Open-Angle Glaucoma or Ocular Hyp NCT01410188 | Kubota Vision Inc. | Phase 1 / Phase 2 |
| Completed | STudy to Assess Rapid Disease Progression by Clinical and Genetic Factors In Glaucoma patientS That Are High R NCT01442896 | University of California, San Diego | — |
| Completed | Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma Patients NCT02077231 | Xiaodong Zhou | N/A |
| Completed | EXTERNAL SLT Treatment in Patients With Uncontrolled OPEN ANGLE GLAUCOMA NCT01384149 | Meir Medical Center | Phase 1 |
| Completed | PIO Laser Sclerectomy IOP SLT Sclerectomy NCT01798732 | University Hospital, Grenoble | N/A |
| Completed | Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surger NCT02024464 | Ivantis, Inc. | N/A |
| Completed | Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sens NCT01390779 | Sensimed AG | N/A |
| Completed | Comparison of Sensimed Triggerfish With Goldmann Applanation Tonometry and Perkins Tonometry NCT01391078 | Katrin Lorenz | N/A |
| Completed | Safety and Performance of Miami InnFocus Drainage Implant (MIDI Arrow) Glaucoma Drainage Implant NCT01563237 | InnFocus Inc. | N/A |
| Unknown | a 3.0T Magnetic Resonance Imaging Study NCT01346904 | Huazhong University of Science and Technology | — |
| Completed | RESEARCH PROTOCOL: Glaucoma Treatment Adherence and Persistence NCT01409421 | University of Colorado, Denver | N/A |
| Completed | Latanoprost Versus Tafluprost: 24-hour Intraocular Pressure (IOP) NCT01162603 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | Phase 4 |
| Completed | Safety and Efficacy Trial to Evaluate the Hydrus(TM) Implant in Subjects Undergoing Cataract Surgery. NCT01818115 | Ivantis, Inc. | N/A |
| Completed | The Effects of Caffeinated Coffee on Intraocular Pressure NCT01364207 | Massachusetts Eye and Ear Infirmary | N/A |
| Terminated | Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube NCT01301378 | Wills Eye | N/A |
| Completed | 24h Continuous Intraocular Pressure (IOP) Monitoring vs Goldmann Applanation Tonometry NCT01217853 | Sensimed AG | — |
| Completed | A Study of Ganfort Versus Duotrav in Patients With Primary Open Angle Glaucoma or Ocular Hypertension NCT01168414 | Ministry of Health, Malaysia | Phase 3 |
| Completed | Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patient NCT01110499 | Allergan | Phase 2 |
| Completed | Transconjunctival Needling Revision Versus Medical Treatment NCT01887223 | University of Sao Paulo General Hospital | Phase 2 |
| Completed | Safety and Efficacy Study of the Hydrus Aqueous Implant in Subjects With POAG NCT03065036 | Ivantis, Inc. | Phase 1 / Phase 2 |
| Withdrawn | The Antioxidant Effect of Routine Vascular Therapy for Normal Tension Glaucoma Patients NCT00465348 | University Hospital, Basel, Switzerland | — |
| Completed | Efficacy And Safety of Pneumatic Trabeculoplasty NCT01540331 | University of Catanzaro | Phase 4 |
| Completed | Adherence With Fixed Versus Unfixed Glaucoma Therapy NCT01281020 | Aristotle University Of Thessaloniki | — |
| Unknown | Contrast Sensitivity in Glaucoma NCT00947869 | University of Erlangen-Nürnberg | — |
| Withdrawn | Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Maximum Tolerated Medical Therapy NCT00864578 | Sooft Italia | — |
| Withdrawn | Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Treatment With Either Beta-blocker NCT00863811 | Sooft Italia | — |
| Unknown | Protective Effect of Phenytoin on Glaucoma NCT00739154 | Rabin Medical Center | — |
| Unknown | Comparison of Retinal Nerve Fiber Layer (RNFL) Thickness Measurements by Time-Domain and Spectral-Domain OCT I NCT00773877 | Yonsei University | — |
| Unknown | Efficacy of Retinal Nerve Fiber Layer (RNFL) / Ganglion Cell Layer Thickness Ratio by RT-View Utilizing Spectr NCT00773123 | Yonsei University | — |
| Completed | Pharmacokinetics, Efficacy and Safety Assessment of T2345 Compared With Active Comparator in Newly Diagnosed P NCT01494753 | Laboratoires Thea | Phase 2 |
| Completed | Glaucoma Adherence Study NCT00676637 | Alcon Research | — |
| Completed | Glaucoma Adherence Study, Spain NCT00680329 | Alcon Research | — |
| Completed | How Does Your Genetic Make-up (Profile) Influence Your Glaucoma? NCT00626847 | Wills Eye | — |
| Completed | Transcorneal Electrical Stimulation Therapy for Retinal Disease NCT00804102 | Okuvision GmbH | N/A |
| Completed | Safety and Efficacy of PF-04217329 in Patients With Glaucoma or Elevated Eye Pressure. NCT00572455 | Pfizer | Phase 2 |
| Completed | A Phase 2, Dose Finding Study of PF-03187207 in Patients With Primary Open Angle Glaucoma or Ocular Hypertensi NCT00595101 | Bausch & Lomb Incorporated | Phase 2 |
| Completed | Dose-Finding Study Comparing the Safety and Efficacy of Latanoprost to a Novel Treatment for Glaucoma NCT00441883 | Bausch & Lomb Incorporated | Phase 2 |
| Completed | Anti-inflammatory Therapy Following Selective Laser Trabeculoplasty NCT00485108 | Queen's University | N/A |
| Completed | Correlation of Optic Disk Morphology and Ocular Perfusion Parameters in Patients With Primary Open Angle Glauc NCT00803504 | Medical University of Vienna | — |
| Unknown | Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early Glaucoma NCT00476138 | Catholic University of the Sacred Heart | Phase 1 / Phase 2 |
| Completed | Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients W NCT00300079 | Alcon Research | Phase 4 |
| Unknown | External Micropulse Diode Laser Transscleral Trabeculoplasty (EMDLT) for Severe Open Angle Glaucoma NCT00443664 | National University Hospital, Singapore | EARLY_Phase 1 |
| Unknown | The Efficacy of Selective Laser Trabeculoplasty NCT00347893 | Glaucoma Research & Education Group | — |
| Completed | 24-Hour Intraocular Pressure (IOP) And Blood Pressure Control In Glaucoma And Ocular Hypertension Patients NCT00330577 | Aristotle University Of Thessaloniki | Phase 4 |
| Completed | 24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed Combination NCT00331240 | Aristotle University Of Thessaloniki | Phase 3 |
| Withdrawn | Choroidal Blood Flow Response to Hand-grip Test in Progressive Glaucoma NCT00284440 | University Hospital, Basel, Switzerland | — |
| Completed | Autoimmune Dysregulation in Pigmentary Glaucoma NCT00280345 | University of Oklahoma | N/A |
| Completed | Clinical Study of A Fixed Combination of Timolol-Brimonidine-Dorzolamide NCT01062971 | Laboratorios Sophia S.A de C.V. | Phase 2 |
| Completed | Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs NCT00675207 | Northwestern Ophthalmic Institute S.C. | Phase 4 |
| Terminated | Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular Pressure NCT00346931 | Medical University of Vienna | N/A |
| Completed | Study of Brinzolamide and Timolol When Added to Travoprost in Primary Open-angle Glaucoma or Ocular Hypertensi NCT00372827 | Alcon Research | Phase 4 |
| Completed | A Study Comparing The Efficacy, Safety And Tolerability Of Latanoprost 75, 100 And 125 ug/ml To Xalatan In The NCT01379144 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 2 |
| Unknown | African Descent and Glaucoma Evaluation Study NCT00221923 | University of California, San Diego | — |
| Recruiting | A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraoc NCT07076303 | Brian Shafer | — |
| Unknown | Early Diagnosis, Pathogenesis and Progression of Open Angle Glaucoma NCT00494923 | University of Erlangen-Nürnberg Medical School | — |
| Completed | Intraoperative 5-fluorouracil Augmentation of Trabeculectomy NCT06745856 | Moorfields Eye Hospital NHS Foundation Trust | Phase 3 |
| Recruiting | Diagnostic Innovations in Glaucoma Study NCT00221897 | University of California, San Diego | — |
| Completed | Results of Ocular Compression and Suture Release in Trabeculectomy and Combined Surgery NCT00327405 | University of Cincinnati | — |