| Recruiting | A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hy Obstructive Cardiomyopathy, Hypertrophic, Non-obstructive Hypertrophic Cardiomyopathy | Phase 3 | 2024-09-24 |
| Completed | A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP) Diabetic Peripheral Neuropathic Pain | Phase 2 | 2023-11-29 |
| Completed | Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia Postherpetic Neuralgia | Phase 2 | 2020-12-10 |
| Completed | Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain Diabetic Peripheral Neuropathy, Diabetes | Phase 2 | 2020-09-03 |
| Terminated | Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Fai Heart Failure, Type 2 Diabetes Mellitus | Phase 3 | 2018-06-15 |
| Terminated | Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes M Type 2 Diabetes Mellitus | Phase 3 | 2018-02-19 |
| Terminated | Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate R Heart Failure, Type 2 Diabetes Mellitus, Chronic Kidney Diseases | Phase 3 | 2017-12-19 |
| Terminated | Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Participants With Cardiac Failure Aggravated | Phase 2 | 2017-12-04 |
| Completed | Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Melli Type 2 Diabetes Mellitus | Phase 3 | 2017-12-01 |
| Completed | Study to Evaluate the Pharmacokinetics of Telotristat Ethyl in Subjects With Severe Hepatic Impairment Hepatic Impairment | Phase 1 | 2017-11-28 |
| Completed | Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mel Type 2 Diabetes Mellitus | Phase 3 | 2017-11-27 |
| Completed | A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Drug-drug Interaction | Phase 1 | 2017-09-21 |
| Completed | Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Ina Type 2 Diabetes Mellitus | Phase 3 | 2017-09-15 |
| Completed | A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes Mellitus, Chronic Kidney Disease Stage 4 | Phase 3 | 2017-08-16 |
| Completed | Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate I Type 2 Diabetes Mellitus, Chronic Kidney Disease Stage 3 | Phase 3 | 2017-08-16 |
| Completed | Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Backgroun Type 2 Diabetes Mellitus | Phase 3 | 2017-02-24 |
| Completed | Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Tr Type 2 Diabetes Mellitus | Phase 3 | 2016-11-11 |
| Completed | Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Type 2 Diabetes Mellitus | Phase 3 | 2016-11-01 |
| Completed | Study to Evaluate Sotagliflozin in Subjects With Varying Degrees of Renal Function Renal Impairment, Healthy | Phase 1 | 2015-12-01 |
| Completed | A Phase 3 Study to Evaluate the Safety of Sotagliflozin in Patients With Type 1 Diabetes Who Have Inadequate G Type 1 Diabetes Mellitus (T1DM), High Level of Sugar (Glucose) in the Blood | Phase 3 | 2015-09-01 |
| Unknown | Oral Contraceptive DDI Study Healthy | Phase 1 | 2015-07-01 |
| Completed | Dose-ranging Study in Patients With Type 1 Diabetes Mellitus Type 1 Diabetes Mellitus | Phase 2 | 2015-07-01 |
| Completed | PK Study of Sotagliflozin in Subjects With Hepatic Impairment Hepatic Impairment, Healthy | Phase 1 | 2015-06-01 |
| Completed | Efficacy, Safety, and Tolerability Study of Sotagliflozin as Adjunct Therapy in Adult Patients With Type 1 Dia Type 1 Diabetes Mellitus | Phase 3 | 2015-05-01 |
| Completed | Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemogl Type 1 Diabetes Mellitus | Phase 2 | 2015-04-01 |
| Completed | Efficacy, Safety, and Tolerability Study of Sotagliflozin as Adjunct Therapy in Adult Patients With Type 1 Dia Type 1 Diabetes Mellitus | Phase 3 | 2015-03-01 |
| Completed | Bioequivalence Study Between 400 mg LX4211 Tablets and 2 X 200 mg LX4211 Tablets Healthy | Phase 1 | 2015-02-01 |
| Completed | DDI Study With Multiple-dose LX4211 and Single Dose Digoxin Healthy | Phase 1 | 2014-10-01 |
| Completed | DDI Study With Multiple-dose LX4211 and Single Dose Rosuvastatin Healthy | Phase 1 | 2014-10-01 |
| Completed | Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Drug Interactions | Phase 1 | 2014-07-01 |
| Completed | An Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Fexofenadine in Healthy Subjects Drug Interactions | Phase 1 | 2014-07-01 |
| Completed | An Open-Label Food Effect Study of Telotristat Etiprate Healthy | Phase 1 | 2014-06-01 |
| Completed | A Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Midazolam in Healthy Subjects Drug Interactions | Phase 1 | 2014-05-01 |
| Completed | A Thorough QT Study of Telotristat Etiprate QT Interval | Phase 1 | 2014-05-01 |
| Completed | Telotristat Etiprate for Carcinoid Syndrome Therapy Carcinoid Syndrome | Phase 3 | 2014-03-11 |
| Completed | Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms Carcinoid Syndrome | Phase 3 | 2014-01-14 |
| Completed | An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Mal Carcinoid Syndrome | Phase 1 | 2013-08-01 |
| Completed | Study to Evaluate the Effect of Single Doses of LX4211 and Canagliflozin on Intestinal Glucose Absorption in H Healthy Subjects | Phase 1 | 2013-08-01 |
| Completed | Study to Determine the Safety, Tolerability and Pharmacokinetics Following Multiple Doses of LX4211 in Healthy Healthy | Phase 1 | 2013-08-01 |
| Completed | Study to Define the Electrocardiogram Effects of a Single Dose of LX4211 in Healthy Subjects Healthy | Phase 1 | 2013-07-01 |
| Completed | Study to Determine the Absorption, Metabolism, and Excretion of [14C]LX4211 in Healthy Male Subjects Healthy | Phase 1 | 2013-03-01 |
| Completed | Safety and Efficacy of Sotagliflozin (LX4211) in Patients With Inadequately Controlled Type 1 Diabetes Mellitu Type 1 Diabetes Mellitus | Phase 2 | 2013-02-01 |
| Completed | TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome) Carcinoid Syndrome | Phase 3 | 2013-01-08 |
| Completed | Study to Evaluate the Safety, Tolerability, and Efficacy of LX7101 in Subjects With Primary Open-angle Glaucom Primary Open-angle Glaucoma, Ocular Hypertension | Phase 1 / Phase 2 | 2012-03-01 |
| Completed | Study to Evaluate the Pharmacodynamic and Pharmacokinetic Effects of LX4211 in Subjects With Type 2 Diabetes a Type 2 Diabetes Mellitus, Renal Impairment | Phase 1 | 2012-03-01 |
| Completed | A Multi-Center Trial to Determine the Safety and Efficacy of LX1033 in Subjects With Diarrhea-Predominant Irri Irritable Bowel Syndrome | Phase 2 | 2012-02-01 |
| Completed | A Study to Evaluate Safety and Efficacy of Telotristat Etiprate (LX1606) in Participants With Acute, Mild to M Ulcerative Colitis | Phase 2 | 2012-01-30 |
| Completed | A Study to Evaluate the Pharmacodynamic Effects of Single-Dose Co-Administration of LX4211 With Januvia® in Ty Type 2 Diabetes Mellitus | Phase 1 | 2011-10-01 |
| Completed | A Study to Determine the Safety and Efficacy of LX3305 in Subjects With Active Rheumatoid Arthritis Rheumatoid Arthritis | Phase 1 | 2011-09-01 |
| Completed | An Open-Label Study of Two Formulations of LX1033 in Healthy Human Subjects Irritable Bowel Syndrome | Phase 1 | 2011-08-01 |
| Completed | Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on M Type 2 Diabetes Mellitus | Phase 2 | 2011-06-01 |
| Completed | A Study to Determine the Pharmacodynamics of LX4211 Relative to Meals in Healthy Subjects Healthy | Phase 1 | 2011-03-01 |
| Completed | A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects Type 2 Diabetes Mellitus | Phase 1 | 2011-02-01 |
| Completed | Study of Two Oral Formulations of LX4211 in Patients With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 1 | 2010-09-01 |
| Completed | Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Carcinoid Syndrome | Phase 2 | 2010-06-15 |
| Completed | Study of LX4211 in Subjects With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 2 | 2009-08-01 |
| Completed | Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate Rheumatoid Arthritis | Phase 2 | 2009-07-01 |
| Completed | Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stab Carcinoid Syndrome | Phase 2 | 2009-03-01 |
| Completed | Study of LX3305 and Methotrexate in Subjects With Stable Rheumatoid Arthritis Rheumatoid Arthritis | Phase 1 | 2009-02-01 |
| Completed | Study of LX1031 in Subjects With Non-Constipating Irritable Bowel Syndrome Irritable Bowel Syndrome | Phase 2 | 2008-12-01 |
| Completed | Study of LX6171 in Elderly Volunteers With Age Associated Memory Impairment Age-Related Memory Disorders | Phase 2 | 2008-02-01 |