NCT00626847

How Does Your Genetic Make-up (Profile) Influence Your Glaucoma?

Nuclear Genetic and Mitochondrial Influences in Glaucoma

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 97 (actual)
• Sponsor: Wills Eye · Academic / Other
• Sex: All
• Age: 40 Years
• Healthy volunteers: Accepted

Summary

Glaucoma is a group of diseases in which visual loss occurs because of damage to the optic nerve. Research has shown that certain genes may cause glaucoma in some cases. So far, research has only been able to find the genes responsible for glaucoma in a small percentage of people who have glaucoma. The purpose of this project is to study the genes in patients with and without glaucoma to find additional genes that may be responsible for causing glaucoma.

Detailed description

Four tubes of blood will be taken from 100 people. Of those, half will have primary open angle glaucoma (POAG) and the other half will be controls (normals), half will be caucasians and the other half will be african americans, half male and half female. All groups will have a routine ophthalmic eye exam, color vision, snellen vision, and visual field done.

Conditions

• Primary Open Angle Glaucoma

Timeline

• Start date: 2008-03-01
• Primary completion: 2009-08-01
• Completion: 2009-08-01
• First posted: 2008-02-29
• Last updated: 2016-11-21

Locations

1 site across 1 country: United States