Trials / Recruiting
RecruitingNCT04957329
Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells
Department of Ophthalmology, Rigshospitalet-Glostrup Valdemar Hansens Vej 13, 2600 Glostrup, Denmark
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 28 (estimated)
- Sponsor
- Rigshospitalet, Denmark · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
a randomized, investigator-blind, interventinal study will compare the effect of benzalkonium-chloride (BAK) preserved and preservative-free (PF) eye drops on conjunctival goblet cells.
Detailed description
The investigators will conduct a randomized, investigator-blind, interventinal study on 28 subjects. Each subject will apply a benzalkonium-chloride (BAK) preserved eye drop (Xalatan) in one eye and a preservative-free (PF) eye drop (Monoprost) in the other for 3 months. Which eye gets which treatment is randomized. Before and after treatment a conjunctival print will be made and the effect of the eye drops on goblet cell density will be evaluated along with effect on the intraocular pressure.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Xalatan | Eye drop |
| DRUG | Monoprost | Eye drop |
Timeline
- Start date
- 2021-09-01
- Primary completion
- 2026-12-31
- Completion
- 2026-12-31
- First posted
- 2021-07-12
- Last updated
- 2023-11-18
Locations
2 sites across 1 country: Denmark
Source: ClinicalTrials.gov record NCT04957329. Inclusion in this directory is not an endorsement.