NCT05273385

Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With Glaucoma

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Glaucoma is the leading cause of irreversible blindness worldwide. Previous studies demonstrate that smaller eye drops used in the treatment of glaucoma are just as efficacious as their larger counterparts. The proposed study hopes to demonstrate the non-inferiority of using Nanodropper to lower intraoccular pressure (IOP) in glaucoma patients compared to standard of care eye drops.

Detailed description

The proposed study strives to demonstrate the non-inferiority of using Nanodropper to lower IOP in glaucoma patients compared to standard of care (SOC) eye drops in a randomized trial. Primary Aim: Demonstrate non-inferiority of using Nanodropper to lower IOP compared to standard of care eye drops in glaucoma patients. Stable glaucoma participants and ocular hypertension participants of ages 18+ will be randomized to either use Nanodropper for eye drop administration in both eyes OR administer drops regularly (standard of care) in both eyes. Participants will be followed-up at 1 month and 3 months.

Conditions

• Glaucoma
• Ocular Hypertension
• Open Angle Glaucoma

Interventions

Type	Name	Description
DEVICE	Nanodropper	Device to apply liquid medication to eyes

Timeline

• Start date: 2022-10-10
• Primary completion: 2024-12-10
• Completion: 2024-12-10
• First posted: 2022-03-10
• Last updated: 2026-03-05
• Results posted: 2026-03-05

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study