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UnknownNCT04682054

Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
80 (estimated)
Sponsor
The First Affiliated Hospital with Nanjing Medical University · Academic / Other
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The surgically-harvested eye tissue (ie. vitreous-retinal proliferative membrane, outflow pathway, retinas, and pterygium) is a complex tissue responsible for maintaining intraocular homeostasis or mediating ocular pathogenesis. Dysfunction of one or more resident cell types within the tissues results in different ocular disorder, leading to vision loss, or even blindness. In this study, we aim to use single-cell RNA sequencing to generate a comprehensive cell atlas of surgically-harvested eye tissues.

Conditions

Interventions

TypeNameDescription
PROCEDUREocular surgerysurgery to remove the pathological eye tissue

Timeline

Start date
2021-01-15
Primary completion
2021-12-31
Completion
2021-12-31
First posted
2020-12-23
Last updated
2020-12-23

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04682054. Inclusion in this directory is not an endorsement.

Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics (NCT04682054) · Clinical Trials Directory