Trials / Completed
CompletedNCT05080153
Effect of Vitamin Supplementation in Glaucoma Patients
The Effects of Vitamin Supplementation Containing L-Methylfolate (Ocufolin® Forte) on Retinal Venous Pressure and Homocysteine Plasma Levels in Patients With Glaucoma
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 26 (actual)
- Sponsor
- Devogelaere Vision · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The impact of targeted vitamin supplementation on retinal venous pressure (RVP) and steady state pattern ERG (SSpERG) in patients with RVP 15mmHg or more above intra-ocular pressure (IOP) and serum homocystein 12µmol/l or more, with signs of progression in spite of adequate IOP control, as evidenced by SSpERG abnormality with or without structural progression or visual field progression,
Detailed description
Provided the inclusion criteria were met, RVP measurement was repeated, and a 1 capsule/day regimen of Ocufolin® forte was subsequently carried out for a duration of 3 months, after which repeat measurements of IOP, SSpERG, and RVP were performed, along with dilated fundoscopy. .
Conditions
- Glaucoma
- Homocysteinemia
- Elevated Retinal Venous Pressure
- Abnormal Steady State Pattern Electroretinography
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Ocufolin forte | start of ocufolin forte 1 dd after RVP measurement, till 90 tablets are finished (3 months) |
Timeline
- Start date
- 2019-11-15
- Primary completion
- 2020-10-31
- Completion
- 2021-06-30
- First posted
- 2021-10-15
- Last updated
- 2021-10-15
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT05080153. Inclusion in this directory is not an endorsement.