NCT05626426

Electrical Stimulation for the Treatment of Optic Neuropathies

An Open-Label Study to Evaluate the Safety and Efficacy of Repetitive, Transorbital Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The overall aim of this study is to see whether long-term electrical stimulation with a home-stimulation device works well and is safe for the treatment of open-angle glaucoma. Open-Angle Glaucoma is a disease where the nerves in the back of your eye die off faster than expected regardless of your eye pressure.

Detailed description

This is a concurrent open-label study for patients who are deemed safe to participate in the electrical stimulation trial but do not fit the exact criteria for the randomized clinical trial.

Conditions

• Glaucoma
• Glaucoma, Open-Angle
• Optic Nerve Diseases

Interventions

Type	Name	Description
DEVICE	Repetitive, Transorbital Alternating Current Stimulation (rtACS)	Patients receive treatment every other day via a headband that delivers electrical stimulation to the retina

Timeline

• Start date: 2023-02-27
• Primary completion: 2026-12-01
• Completion: 2027-12-01
• First posted: 2022-11-23
• Last updated: 2025-07-08

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study