| Not Yet Recruiting | Building Adaptive School-based Interventions for Caries NCT07265830 | University of Pennsylvania | Phase 3 |
| Not Yet Recruiting | Occlusal Changes After Modified Hall Technique in Molars Affected by Molar-Incisor Hypomineralization NCT07530835 | Ankara Yildirim Beyazıt University | N/A |
| Not Yet Recruiting | Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences NCT07124533 | Loma Linda University | Phase 3 |
| Not Yet Recruiting | Clinical Performance of Four Restorative Materials in Primary Molars NCT07504393 | Al-Azhar University | N/A |
| Not Yet Recruiting | Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study. NCT07476417 | University of Milan | — |
| Not Yet Recruiting | Vertical Dimension Changes After Bioflx vs Stainless Steel Crowns in Primary Molars NCT07523776 | Cairo University | N/A |
| Enrolling By Invitation | Effect of Ferric Sulphate and Putty MTA as Pulpotomy Agent in Vital Primary Teeth NCT07324928 | University of Jazan | N/A |
| Recruiting | Involvement of Archaea in Carious Disease NCT06787261 | Assistance Publique Hopitaux De Marseille | N/A |
| Not Yet Recruiting | DETERMINATION OF THE EFFECTS OF STAINLESS STEEL CROWNS CEMENTED WITH RESIN CEMENTS ON INTERLEUKIN-10, 12, 18 L NCT07421206 | Afyonkarahisar Health Sciences University | N/A |
| Recruiting | Mothers' Action Project for Child Health NCT06753669 | University of Massachusetts, Worcester | N/A |
| Not Yet Recruiting | Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental NCT07363317 | Rana Mohamed Ahmed Farghal | N/A |
| Not Yet Recruiting | Minimally Invasive Protocols for the Treatment and Control of Caries Lesions in Children and Adolescents NCT06999005 | University of Nove de Julho | N/A |
| Not Yet Recruiting | Clinical Evaluation of Flowable Monochromatic and Polychromatic Composite Resins in Posterior Restorations NCT07289022 | Istanbul University | N/A |
| Recruiting | Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics NCT07244991 | Cardenal Herrera University | N/A |
| Not Yet Recruiting | Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure NCT07231237 | Solventum US LLC | N/A |
| Recruiting | A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling The NCT07212660 | Ivoclar Vivadent AG | N/A |
| Completed | Effect of Silver Diamine Fluoride and LED Activation on Residual Caries Activity in Class II Cavities NCT07250009 | Çanakkale Onsekiz Mart University | N/A |
| Not Yet Recruiting | Oral-Spray Bacillus Spore Probiotic in Preventing and Supporting Treatment of Dental Caries in Children NCT07241052 | Anabio R&D | N/A |
| Not Yet Recruiting | Gluma Compared With Bonding Agent for Post-operative Sensitivity Following Composite Restorations NCT07188142 | Beenish Hassan | Phase 2 / Phase 3 |
| Enrolling By Invitation | Clinical Evaluation of Wear Resistance and Bioactivity of Self Cured Bioactive Resin Composite NCT07262086 | Suez Canal University | N/A |
| Enrolling By Invitation | 3D Scanning as an Advanced Tool for Identifying Tooth Lesions in Children NCT06829550 | Indiana University | N/A |
| Active Not Recruiting | Effect Of Silverdiamine Fluoride Gel, Sodium Fluoride With CPP-ACP, APF On Early Childhood Caries - A Randomis NCT07371117 | University of Jazan | Phase 2 |
| Not Yet Recruiting | Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children NCT07186673 | Tishreen University | N/A |
| Completed | Er,Cr:YSGG Laser Versus Conventional Preparation for Minimally Invasive Caries Removal NCT07493278 | Medical University of Sofia | N/A |
| Recruiting | LT Comparative Effectiveness of 2 Caries Treatments NCT07213661 | Case Western Reserve University | N/A |
| Not Yet Recruiting | Pilot and Feasibility Study of Impact of SDF 38% Application on Oral Health of Elderly With Autonomy Loss NCT07194629 | Université de Montréal | Phase 4 |
| Active Not Recruiting | Effects of Different Remineralization Agents on the Progression of Non-Cavitated Approximal Carious Lesions in NCT07431463 | Izmir Katip Celebi University | N/A |
| Not Yet Recruiting | The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional NCT06990945 | Cairo University | N/A |
| Active Not Recruiting | In-situ Clinical Trial Assessing Ability to Detect and Monitor Active Caries and Their Remineralization NCT07100626 | Incisive Technologies Pty Ltd | N/A |
| Recruiting | Occlusal Impact of Hall Crowns in Primary Molars NCT07134114 | Ankara Yildirim Beyazıt University | N/A |
| Active Not Recruiting | BioHPP and Lithium Disilicate Onlay Restorations: Clinical Evaluation NCT07142031 | Ege University | N/A |
| Recruiting | SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children NCT07181967 | Assiut University | N/A |
| Completed | Miswak (Salvadora Persica) Versus a Toothbrush in Plaque Removal NCT07409610 | King Abdulaziz University | N/A |
| Not Yet Recruiting | Hall Technique vs Conventional Technique in Permanent Teeth NCT07100028 | Hacettepe University | N/A |
| Not Yet Recruiting | Obesity and Oral Diseases in Adult Patients NCT04602572 | University of Bergen | — |
| Recruiting | Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions. NCT06944028 | Karolinska Institutet | N/A |
| Not Yet Recruiting | Parental Satisfaction of Hall Technique for Caries Management in Primary Molars NCT07148401 | National Research Centre, Egypt | N/A |
| Not Yet Recruiting | Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars NCT06971055 | Cairo University | N/A |
| Not Yet Recruiting | Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars NCT07052526 | Mansoura University | N/A |
| Recruiting | Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-C NCT07031856 | Cukurova University | N/A |
| Completed | Comparative Evaluation of Clinical Success of BIOFLX Crowns and SSC in Primary Molars NCT07465211 | satish vishwanathaiah | N/A |
| Recruiting | Efficacy and Safety Evaluation Study of Implants With Periodontal Ligament NCT07302581 | OrganTech, Inc. | N/A |
| Enrolling By Invitation | Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children NCT07011381 | Kafrelsheikh University | — |
| Not Yet Recruiting | Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxi NCT06889363 | Cairo University | Phase 2 |
| Completed | Clinical Success of Two Stainless Steel Crowns in Children Treated Under General Anesthesia NCT07393854 | Bezmialem Vakif University | — |
| Completed | Perceptions of Parents and Children on Posterior Restorations in Primary Molars NCT07402967 | Universiti Teknologi Mara | — |
| Not Yet Recruiting | AI-Based Detection of Dental Caries in Children NCT06984029 | Noura Nageh Ramadan Ahmed | — |
| Not Yet Recruiting | Microbiome Changes After Laser and Chlorhexidine Disinfection in Caries Removal NCT06765330 | Mersin University | N/A |
| Not Yet Recruiting | Effectiveness of Coconut Oil Pulling With Clove Oil, Coconut Oil Pulling and Fluoride Mouthwash on Streptococc NCT06902532 | Cairo University | N/A |
| Not Yet Recruiting | The Effectiveness RMGI and Giomer, Individually and Combined Anterior Cervical Caries NCT06901453 | Cairo University | N/A |
| Not Yet Recruiting | Evaluation of the Salivary-free Amino Acids Levels (Glycine , Proline , Lysine , and Alanine ) With Caries Act NCT06953557 | Al-Mustansiriyah University | — |
| Completed | A Clinical Study to Assess an Experimental Dentifrice in an Experimental Model of Early Stage Caries NCT06949072 | HALEON | N/A |
| Completed | Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste NCT07419763 | Church & Dwight Company, Inc. | N/A |
| Not Yet Recruiting | CARIES ARREST USING SILVER DIAMINE FLUORIDE VERSUS FISSURE SEALANT in OCCLUSAL DENTAL CARIOUS LESIONS: RANDOMI NCT06861725 | Cairo University | N/A |
| Not Yet Recruiting | The Effect of Bulk Filling Flowable Composite on Caries Recurrence in Deep Marginal Elevation: A Randomized Cl NCT06900868 | Future University in Egypt | N/A |
| Not Yet Recruiting | Comparing Fluorescent Starch Nanoparticles Rinse with ICDAS for Early Caries Detection in Children NCT06761248 | Cairo University | N/A |
| Not Yet Recruiting | Antimicrobial Effect of Curcumin Versus Chlorohexidine on Oral Microbiome NCT06847984 | Cairo University | N/A |
| Not Yet Recruiting | Comparison of the Functional Properties of Two Injectable Materials in Posterior Teeth: Randomized Clinical Tr NCT06894186 | Future University in Egypt | N/A |
| Active Not Recruiting | Survival Rate and Cost-effectiveness of Conventional vs ART Restorations in a School Setting NCT05766696 | DMG Dental Material Gesellschaft mbH | N/A |
| Recruiting | Polymer Induced Liquid Precursor (PILP) in Adults in With Dentin Caries NCT06727110 | University of California, San Francisco | N/A |
| Completed | Masticatory Performance in Mixed Dentition Children Before and After Dental Treatment NCT07271901 | TC Erciyes University | N/A |
| Not Yet Recruiting | Clinical Performance of Bioactive Highly Filled Injectable Flowable Composite for Direct Posterior Occlusal Co NCT06790511 | Cairo University | EARLY_Phase 1 |
| Completed | Association Between Gastroesophageal Reflux Disease (GERD) Severity and Dental Caries NCT07108751 | Tanta University | — |
| Completed | Evaluation of Clinical and Radiographic Performance, and Parental and Children's Satisfaction of BioFlx Crowns NCT07471360 | King Abdulaziz University | N/A |
| Not Yet Recruiting | Evaluation of Bioactive Giomer Material Versus Nanohybrid Resin Composite in Deep Marginal Elevation NCT06497231 | Cairo University | N/A |
| Active Not Recruiting | Evaluation of Prefabricated CAD/CAM PEEK Crowns Used in Primary Molars NCT06583759 | Alexandria University | N/A |
| Completed | Maintaining Oral Health With Bio-products NCT04033263 | University of Bern | N/A |
| Not Yet Recruiting | Prevalence of MIH in Young Adults At Cairo University Dental Hospital and Its Link to Dental Cavities: a Cross NCT06701552 | Cairo University | — |
| Active Not Recruiting | Clinical Performance of Bioactive Restorative Materials NCT07394751 | Ege University | N/A |
| Completed | Ozonized Gel vs Gaseous Ozone Against S. Mutans in Deciduos Molars Caries NCT06641323 | University of Pavia | N/A |
| Recruiting | Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars wit NCT06730360 | Mansoura University | N/A |
| Completed | Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste NCT07419685 | Church & Dwight Company, Inc. | N/A |
| Recruiting | Probiotic Treatment of Orthodontic Patients NCT06751979 | University of Aarhus | N/A |
| Completed | Biodentine Pulpotomy vs Metapex Pulpectomy in Primary Molars: Clinical & Radiographic Comparison of Outcomes i NCT06524921 | Mohamed Ahmed Hamdi Abo El Yamin | N/A |
| Active Not Recruiting | Clinical Performance of a Highly-filled Flowable Composite in Class III Restorations. NCT07051551 | Hacettepe University | N/A |
| Recruiting | Oral Health Intervention in Adult Primary Care NCT06555029 | Case Western Reserve University | N/A |
| Enrolling By Invitation | Indirect Pulp Capping Versus Hall Crown Technique for the Management of Deep Dentinal Caries of Primary Molars NCT07136155 | King Abdullah University Hospital | N/A |
| Enrolling By Invitation | Selective Versus Non-selective Caries Excavation in MIH Affected Teeth. NCT07142629 | King Abdullah University Hospital | N/A |
| Active Not Recruiting | Supervised Toothbrushing and Oral Health Education in Primary Schools in Saudi Arabia NCT07091578 | Fatimah Alshehri | N/A |
| Active Not Recruiting | Comparison of LSTR and Pulpectomy in Primary Molars of Pediatric Patients (LSTR-PULP) NCT07026435 | taymour abuawwad | N/A |
| Recruiting | Advancing Water Security: A Community Participatory School-Based Hydration Intervention NCT06714929 | Virginia Commonwealth University | N/A |
| Completed | Intra Oral Application (IOA) Testing Study of a Stannous Toothpaste NCT07419672 | Church & Dwight Company, Inc. | N/A |
| Completed | Comparative Effectiveness of Remineralization Agents on Attachment-Associated Demineralization in Clear Aligne NCT07229105 | Bezmialem Vakif University | N/A |
| Not Yet Recruiting | Accuracy of an Artificial Intelligence-assisted Diagnostic System for Caries Diagnosis: a Prospective Multicen NCT06428344 | Zhejiang Provincial People's Hospital | — |
| Completed | Traditional vs. Minimally Invasive Decay Treatments in Primary Molars: An 18-month Split-mouth Randomized Stud NCT07447583 | TC Erciyes University | N/A |
| Recruiting | Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars NCT06685640 | Aydin Adnan Menderes University | N/A |
| Completed | Kissing as a Protective Factor Against Acidic pH in Saliva NCT06501729 | Universidad Catolica Santiago de Guayaquil | N/A |
| Recruiting | Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo Univer NCT06365281 | Cairo University | — |
| Completed | Sleep Problems, Salivary Biomarkers, Dental Caries and Periodontal Status in School-Aged Children NCT07427004 | Bezmialem Vakif University | — |
| Completed | Salivary Antimicrobial Peptides and Severe Early Childhood Caries in Turkish Children NCT07414030 | Bezmialem Vakif University | — |
| Active Not Recruiting | Alkaline Water and Salivary Bacterial Count NCT06511336 | Pharos University in Alexandria | Phase 3 |
| Recruiting | Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Car NCT06558955 | National University of Singapore | N/A |
| Completed | Zirconia-based Primary Anterior Crowns With Retention Grooves Versus Without Retention Grooves NCT06354647 | Virginia Commonwealth University | N/A |
| Completed | Resin Polymer (NuSmile BioFlx) Compared to Stainless Steel Crowns (3M ESPE) for Restoration of Primary Molar T NCT06354634 | Virginia Commonwealth University | N/A |
| Recruiting | The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Mola NCT06608563 | University of Dublin, Trinity College | N/A |
| Not Yet Recruiting | Class II Restorations With High-Filled Flowable Composites NCT06346795 | Selcuk University | N/A |
| Completed | Bioactive Versus Non-Bioactive Restorative System in Deep Carious Molars NCT06348953 | Cairo University | N/A |
| Completed | Comparative Effectiveness of Various Educational Approaches on Oral Hygiene NCT06910501 | Ege University | N/A |
| Recruiting | Comparing Stainless Steel Crowns with Prefabricated Resin Crowns in Primary Molar Teeth NCT06713330 | Children's Hospital Medical Center, Cincinnati | N/A |
| Recruiting | Prevalence of Long-term Dental Effects of Chemotherapy in Childhood Cancer Survivors Diagnosed With Cancer Bef NCT06517927 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Completed | Detection of Non-cavitated Occlusal Caries Lesions by Visual Inspection, LF, QLF and NILT NCT07532291 | Neslihan Atmaca | — |
| Recruiting | Effectiveness of Two Health Education Interventions in the Prevention of Caries and Gingivitis in Orthodontic NCT05979805 | Universidad Nacional de Colombia | N/A |
| Enrolling By Invitation | Treating Children With Extensive Dental Needs NCT06863103 | Malmö University | — |
| Completed | Sealant Application by Interns After Tele-demonstration NCT07232797 | Mansoura University | N/A |
| Recruiting | Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventi NCT07101068 | Ain Shams University | N/A |
| Recruiting | Oral Health and Dental Caries Prevention Intervention for Children in Romania NCT06441500 | University of Medicine and Pharmacy "Victor Babes" Timisoara | N/A |
| Completed | Evaluation of Oral and Dental Health of Institutionalized Orphan Children Residing in Children's Homes in Turk NCT06725654 | Cumhuriyet University | — |
| Completed | The Impact of Sage Extract on GTS B and D Gene Expression in S. Mutans NCT06703554 | Cairo University | N/A |
| Unknown | Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore NCT06169306 | Cukurova University | N/A |
| Suspended | Efficacy of Two Protocols for Applying Fluorine Varnish to Deciduous Teeth NCT03827889 | Universidade Ibirapuera | N/A |
| Completed | Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Gla NCT06003452 | Cairo University | N/A |
| Completed | Association Between Primary School Children's Speaking Attitudes and Oral Health Indicators NCT07271810 | Ezgi Turkyilmaz | — |
| Completed | The Use of Artificial Intelligence in the Dental X-rays Analysis NCT06258798 | Hospital of the Ministry of Interior, Kielce, Poland | — |
| Recruiting | A Randomized Controlled Trial of Vitamin D Supplementation on Salivary Biomarkers and Cariogenic Oral Microbio NCT06172764 | Dow University of Health Sciences | Phase 4 |
| Completed | Healthy Hydration Pilot in Elementary Schools NCT06132763 | Virginia Commonwealth University | N/A |
| Recruiting | Effect of Silver Diamine Fluoride Application on Oral Microbiome of Healthy Pediatric Patient NCT06699199 | King Abdulaziz University | Phase 4 |
| Completed | The Effect of Arginine on Biofilm Composition, Architecture and Metabolism NCT06135792 | University of Aarhus | N/A |
| Completed | Knowledge, Attitude, Behavior and Prevalence of Dental Caries of Rural Mothers and Their Preparatory School Yo NCT06749717 | Cairo University | — |
| Unknown | Effectiveness of Oral Health Education Programs Among School Children, Their Mothers and Teachers in Fayyum: C NCT05980273 | Cairo University | — |
| Completed | "Comparison of the Effects of Resin Infiltrant, Fluoride Varnish, and the Combined Application of Resin Infilt NCT07112963 | Sacide Duman | N/A |
| Unknown | Knowledge, Attitude and Practice Regarding Caries Risk Assessment for Children and Adults Among Dental Residen NCT05910645 | Cairo University | — |
| Suspended | RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda NCT06081868 | University of Bern | N/A |
| Completed | Implementation of Oral Health Educational Program on Orphan Children NCT06428474 | Pharos University in Alexandria | N/A |
| Unknown | Performance of GIOMER Based Resin Composite NCT06021028 | Cairo University | N/A |
| Not Yet Recruiting | Comparison of Two GIC's in the Restoration of Posterior Class II Lesions in the Primary Dentition NCT05965297 | DMG Dental Material Gesellschaft mbH | N/A |
| Recruiting | This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subse NCT06641011 | Hacettepe University | N/A |
| Active Not Recruiting | Hema Free Versus Hema Containing Adhesives in Posterior Restorations NCT06612021 | Cairo University | N/A |
| Active Not Recruiting | Clinical Performance of Novel Alkasite Restorative Material "Cention Forte" in Class II Restorations NCT06833528 | Hacettepe University | N/A |
| Unknown | Development of a Novel Anti-caries Chewing Gum NCT05946473 | University of Toronto | N/A |
| Completed | Clinical Assessment of Giomer Based Technology Versus Smart Bioactive Restoration in Carious Class V Cavities NCT05466461 | Cairo University | N/A |
| Unknown | A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorat NCT04822233 | The University of Texas Health Science Center, Houston | N/A |
| Completed | A Comparison of the Accurate Diagnosis of the Horizontal & Vertical Bitewing Images NCT04341636 | King Abdulaziz University | N/A |
| Completed | Atraumatic Versus Silver-Modified Atraumatic Restorative Treatment in Primary Molars NCT07023939 | Beirut Arab University | Phase 4 |
| Completed | Comparative Evaluation of Glass Ionomer and Resin-Based Fissure Sealants on Newly Erupted Permanent First Mola NCT07115290 | Gulcin Bulut | N/A |
| Completed | Novel Dental Cements (ALBO-MPCA) in Patients With Caries NCT07507136 | Albos d.o.o. Beograd | N/A |
| Unknown | Antimicrobial Efficacy of Biogenic Gold Nano Particle From Pelargonium Graveolens Leaves Extract Mouthwash for NCT05816512 | Ahmed Yousif Mahdi | N/A |
| Unknown | Clinical Evaluation and Antimicrobial Effect of Papain Based Chemo-mechanical Caries Removal Agents NCT05983900 | Alexandria University | N/A |
| Completed | Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses NCT05601154 | University of Michigan | EARLY_Phase 1 |
| Completed | Clinical Evaluation of Direct and Indirect Composites NCT06667271 | Recep Tayyip Erdogan University | — |
| Completed | Evaluation of Chemo-mechanical Caries Removal Materials in Caries Removal NCT05733923 | Damascus University | N/A |
| Active Not Recruiting | Clinical Comparison of Restorative Materials NCT06637605 | Recep Tayyip Erdogan University | — |
| Active Not Recruiting | Clinical Comparison of Resin-hybrid Ceramic Restorations Produced Using a Computer-aided Design/Computer-aided NCT06496126 | Hacettepe University | N/A |
| Completed | Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD) NCT05096897 | University Hospital, Lille | — |
| Completed | Hydrogen Peroxide Fumigation in Dental Office Environment NCT06100848 | Wroclaw Medical University | N/A |
| Completed | Evaluation of Mineral Trioxide Aggregates and Grape Seeds Extract Effect on Pulpotomy NCT06694064 | Al-Azhar University | N/A |
| Completed | Clinical Evaluation of Class II Restorations NCT06346756 | Selcuk University | N/A |
| Completed | Effectiveness of SDF With Different Post-treatment Protocols in Arresting Dental Caries NCT05655286 | The University of Hong Kong | N/A |
| Recruiting | The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth NCT06276959 | West China College of Stomatology | — |
| Unknown | Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restor NCT06222918 | Hacettepe University | N/A |
| Completed | An Educational Intervention Program to Improve the Oral Health of HIV-Positive Children in Kano, Nigeria. NCT05540171 | Aminu Kano Teaching Hospital | N/A |
| Unknown | A Study to Compare Caries Detection in the Pediatric Population Between the iTero Element 5D System and Bitewi NCT05792631 | Hadassah Medical Organization | N/A |
| Completed | Novamin on Streptococcus Mutans Count in Dental Plaque of High Caries Risk Children NCT05979636 | Hams Hamed Abdelrahman | N/A |
| Completed | Caries Inhibitory Effect of Nano Silver and Tri Calcium Phosphate Varnishes Among Visually Impaired Children NCT06576960 | Hadeer Mohammed Abd El wahab | N/A |
| Completed | Oral Health Educational Program on Oral Hygiene Knowledge and Practices in a Group of Orphan Children NCT06897956 | Cairo University | — |
| Unknown | Clinical Evaluation of Different Resin Composite Restorations NCT05418400 | Al-Azhar University | N/A |
| Unknown | Silver Diamine Fluoride: A Randomized Controlled Trial on Its Effectiveness As A Caries Arresting Agent NCT05008718 | Universiti Teknologi Mara | N/A |
| Unknown | Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth NCT05538559 | Hams Hamed Abdelrahman | N/A |
| Unknown | Clinical Performance and Wear Resistance of Highly Translucent Nano Zirconia Reinforced Glass Ionomer Filling NCT05403008 | Cairo University | N/A |
| Completed | The Effects of Pregnancy on Oral Health NCT06343337 | Muğla Sıtkı Koçman University | N/A |
| Completed | SDF Application in Oral Cancer Patients to Prevent Dental Caries NCT05403125 | Texas A & M University Baylor College Of Dentistry | EARLY_Phase 1 |
| Recruiting | Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools NCT06006429 | CHU de Reims | N/A |
| Completed | Teledentistry Mobile Photos Versus Conventional Clinical Examination for Dental Caries Diagnosis NCT06661837 | Cairo University | — |
| Recruiting | Drug-free Without Toothache. A Study of Free Dental Treatment as a Part of Substance Abuse Treatment NCT05606562 | University Hospital of North Norway | N/A |
| Unknown | Empowering Older Adults for Healthy Living and Better Dental Health NCT04946292 | National University of Singapore | N/A |
| Completed | Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis NCT05631197 | University of Pavia | N/A |
| Unknown | Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics NCT05437432 | Al-Azhar University | N/A |
| Unknown | Telemedicine and Forensic Odontology NCT05305157 | University Hospital, Montpellier | — |
| Completed | Orthodontic Varnish Microbiology Study NCT04528134 | University of California, Los Angeles | N/A |
| Completed | Bedtime Routines and Children's Health NCT05201924 | National Taiwan University | N/A |
| Unknown | Caries Arresting in Primary Molar Teeth Using SDF VS ART NCT05188846 | Ola Adel Abdelfadil Ahmed | Phase 3 |
| Unknown | Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and NCT05772039 | Universiti Sains Malaysia | Phase 4 |
| Completed | Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns NCT06348979 | Cairo University | N/A |
| Completed | Pulpotomy Materials in Primary Molars NCT07120321 | Sacide Duman | N/A |
| Withdrawn | Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement NCT03785769 | Universidade Ibirapuera | N/A |
| Unknown | Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Les NCT05149209 | Cairo University | N/A |
| Completed | Efficacy of 4% Articaine Terminal Anesthesia in the Lateral Jaw Region in Children NCT05423392 | University of Novi Sad | N/A |
| Completed | Effect of Probiotics on Oral Homeostasis During Sugar Stress NCT05073393 | University of Copenhagen | N/A |
| Completed | 3D Scanning and Transillumination vs Conventional Examination to Assess Caries Progression, Stability or Regre NCT05409625 | University of Copenhagen | N/A |
| Completed | Early Childhood Caries Prevention: Effectiveness of Mother-Child Oral Health Care Programme (BASIS) NCT06944977 | NORKHAFIZAH SADDKI | N/A |
| Unknown | Evaluation of Ion Releasing Hybrid Restorative Material NCT04854655 | Cairo University | N/A |
| Completed | The Effect of Aerosol Formed From Tobacco Heating Systems on the Microbiome of Supragingival Dental Biofilm NCT06314100 | University of Rijeka | — |
| Completed | Evaluation of Clinical Success of Restorations Using Different Magnification Aids NCT05959382 | Ataturk University | N/A |
| Completed | Effect of Parental Absence on Child's Dental Anxiety and Behaviors During Dental Treatment NCT05125731 | Ankara Yildirim Beyazıt University | N/A |
| Unknown | ASSESSMENT OF SDF vs. GIC AND HALL TECHNIQUE NCT05117268 | Foundation University Islamabad | N/A |
| Not Yet Recruiting | Clinical Performance of Restorative Materials in Primary Teeth NCT03037814 | Hacettepe University | N/A |
| Unknown | Er:YAG Laser Therapy in Combination With Behaviour Management Technique in Reducing Anxiety Among Paediatric P NCT04924452 | Plovdiv Medical University | N/A |
| Unknown | Clinical Performance of Onlay Restorations After Cervical Margin Relocation (CMR) NCT06155773 | Mansoura University | N/A |
| Completed | Pain and Anxiety Reducing During Dental Treatment in Children Using Video Game on Tablet Device With Joystick. NCT05191836 | Damascus University | N/A |
| Unknown | Remineralization of Dentine Caries Using Two Remineralizing Agents Which Are Nanosilver Fluoride and Casein ph NCT04930458 | University of Baghdad | N/A |
| Unknown | Oral Health and Pregnancy NCT04992754 | University Hospital, Montpellier | — |
| Unknown | the Antibacterial Effect of Zinc ,Silver and Fluoride NCT04329858 | Cairo University | N/A |
| Unknown | Restoration Repairs Using Composite Resin Versus Glass Ionomer in Primary Molars: a Randomized Clinical Trial NCT04491981 | University of Sao Paulo | N/A |
| Completed | Evaluation of the Effect of Self-Assembling Peptide P11-4 NCT05667545 | Egymedicalpedia | Phase 1 |
| Unknown | the Effect of Prenatal Vitamins on the Tooth Structure NCT03598972 | Cairo University | — |
| Unknown | The Impact of Simple Home-based Differential Learning on Oral Hygiene in Children. NCT04905784 | University Medicine Greifswald | N/A |
| Completed | Effects of Nystatin Suspension Oral Application on Oral Microbial Community NCT04550546 | University of Rochester | Phase 1 |
| Unknown | The Relationship Between Body Mass Index, Dental Eruption and Dental Caries Prevalence in School Children NCT05902611 | Al-Azhar University | — |
| Terminated | Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project NCT04556175 | Northern Arizona University | N/A |
| Completed | SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Tri NCT04808557 | University of Pavia | N/A |
| Completed | The Preformed Metal Crowns Placed Using the Hall Technique Versus the Conventional Restoration NCT04818658 | Bahçeşehir University | — |
| Unknown | Clinical Performance of Posterior Indirect Adhesive Restorations NCT04838483 | Okan University | N/A |
| Completed | Contemporary Restorative Materials in Primary Molars NCT06544486 | Akdeniz University | N/A |
| Unknown | Platelet Rich Fibrin(PRF) Injection for Treatment of Dental Pulp Exposure:Randomized Clinical Trial NCT04330768 | Cairo University | N/A |
| Completed | Improving Family's Adherence to Dental Care After DGA (HECC-CAN-study) NCT04898465 | Helsinki University Central Hospital | N/A |
| Completed | Remineralizing Efficacy of Grape Seed Extract in Management of White Spot Lesion in Post Orthodontic Treated P NCT04357093 | Cairo University | N/A |
| Completed | Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride NCT04620252 | University of Michigan | EARLY_Phase 1 |
| Unknown | Parental Knowledge, Attitude and Practice Towards Oral Health of Their Children NCT04571931 | Cairo University | — |
| Completed | A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifri NCT04750902 | Colgate Palmolive | Phase 2 |
| Completed | Evaluation of Preventive Regimens With Different Toothpastes vs Fluoride Varnish & Toothpaste in High Caries P NCT04436913 | Cairo University | N/A |
| Unknown | the NMFACT Caries Index NCT04330794 | Cairo University | N/A |
| Completed | Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth. NCT05361278 | Damascus University | N/A |
| Completed | SDF With or Without Fluoride Varnish for Caries Arrest in Primary Teeth of Young Children NCT07153328 | Beaty Dent | N/A |
| Completed | Oral Health Assessment of Children in CP Class NCT04795258 | University Hospital, Montpellier | — |
| Completed | Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults NCT04756557 | Poznan University of Medical Sciences | N/A |
| Unknown | Preventive Regimens With Herbal and Fluoride Toothpaste on Remineralization in High Caries Patients With Initi NCT04446390 | Cairo University | N/A |
| Completed | Are Diabetics Type 2 More Prone to Dental Caries? NCT04883086 | Queen Mary University of London | — |
| Unknown | Early Caries Lesion Management Observational Study NCT04933331 | CareQuest Institute for Oral Health | — |
| Unknown | On Probiotic, Dental Caries, and Orthodontic Patients NCT04593017 | Göteborg University | N/A |
| Completed | Research on the Characteristics and Application of Lactobacillus Rhamnosus X253 as Oral Probiotics NCT05123651 | Junlebao Dairy Group Co., Ltd. | N/A |
| Unknown | Preventing Early Childhood Caries With Silver Diamine Fluoride NCT04075474 | The University of Hong Kong | Phase 2 |
| Completed | Preventing Caries with Silver Diamine Fluoride NCT04399369 | The University of Hong Kong | Phase 2 |
| Completed | EFFICACY OF MORUS ALBA FRUIT EXTRACTS AND CHLORHEXIDINE ON SALIVARY STREPTOCOCCUS MUTANS AND pH LEVELS NCT05052775 | Ziauddin University | N/A |
| Completed | Evaluation Direct and Indirect Composite Restoration in Hypomineralization Molars. NCT05299489 | Damascus University | N/A |
| Unknown | Evaluation Of Clinical Performance of Self-adhering Flowable Composite vs Conventional Flowable Composite in C NCT04475172 | Cairo University | N/A |
| Enrolling By Invitation | Longevity of Dental Fillings Utilizing 3D Printing NCT04630587 | University of Oulu | N/A |
| Terminated | Clinical Evaluation of Adhese Universal DC in the Indirect Restorative Therapy NCT04475679 | Ivoclar Vivadent AG | N/A |
| Completed | Er:YAG Laser Effects on Microbial Population in Conservative Dentistry NCT04769882 | University Of Perugia | N/A |
| Unknown | Evaluation of Reliability of CarieScan PRO Compared With Digital Radiograph and ICDAS-II in Detection of Cario NCT04438252 | Cairo University | N/A |
| Completed | Dental Caries Prevention by a Natural Product NCT03763578 | Cairo University | N/A |
| Unknown | Ethanolic Extract of Aloe Vera Versus Chlorohexidine as Cavity Disinfectant. NCT04446364 | Cairo University | N/A |
| Completed | Comparison of Silver Modified and Conventional Atraumatic Restorative Treatment Modalities NCT03881020 | Ain Shams University | Phase 4 |
| Suspended | Effectiveness of ART and Conventional Treatment - Practice-based Clinical Trial NCT02568917 | University of Sao Paulo | N/A |
| Completed | Evaluation Of Fluoride Uptake By Dentine Following Silver Diamine Fluoride Under Resin Modified Glass Ionomer NCT04777968 | Cairo University | Phase 4 |
| Completed | Pediatric Fiberglass Crown in Primary Teeth NCT06558734 | Akdeniz University | N/A |
| Completed | Effect of a 2-week Sugar Stress on Bacterial Profiles in Whole Saliva NCT04199897 | University of Copenhagen | N/A |
| Unknown | Comparative Evaluation of the Post Operative Sensitivity of Cention-N(Commercially Available Restorative Mater NCT05185206 | Dr. D. Y. Patil Dental College & Hospital | N/A |
| Completed | Study of People's Profile Living in France Who Could be Interested in the Use of a Nanohydroxyapatite Toothpas NCT05234060 | University Hospital, Montpellier | — |
| Unknown | Effect of Sour Cherry Anthocyanins on Healthy Human Saliva NCT05406011 | University of Debrecen | N/A |
| Unknown | Assessment of the Age, Reasons, Oral Health Status and Dental Treatment Needs of Children in Their First Denta NCT04183777 | Cairo University | — |
| Unknown | Prevelance of Dental Caries in Agroup of Egyption Children Using Caries Assessment Spectrum and Treatment NCT04285931 | Cairo University | — |
| Completed | Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization NCT05779332 | Recep Tayyip Erdogan University Training and Research Hospital | — |
| Completed | Caries Removal in Primary Teeth Using Er:YAG Laser NCT05913258 | King Abdulaziz University | Phase 3 |
| Unknown | Clinical Evaluation of Posterior Indirect Adhesive Restorations NCT04293770 | Okan University | N/A |
| Completed | Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients NCT04710927 | University of Malaya | N/A |
| Completed | Epidemiological Profile of Children With Early Caries. NCT04195607 | University Hospital, Lille | — |
| Unknown | Comparative Evaluation of Effectiveness of Hall Technique and Resin Modified Glass Ionomer Cement in Controlli NCT04355000 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Completed | Bioactive Composite Versus Resin-Modified Glass Ionomer Liners: 2-Year Clinical Trial NCT05470959 | Mansoura University | N/A |
| Unknown | Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP NCT03963791 | Cairo University | N/A |
| Unknown | Reminerlization Potential of GSE Gel versusCPP-ACP in Carious White Spot Lesions in Post Orthodontic Patients NCT03966378 | Cairo University | N/A |
| Completed | Clinical Performance of Bulk Fill Composite With Activa Bioactive Liner NCT04281433 | Al-Azhar University | N/A |
| Completed | Evaluation of the Chemo-mechanical Caries Removal Agent (BRIX3000®) in Primary Molars NCT05427591 | King Abdulaziz University | N/A |
| Completed | Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars NCT05438381 | Mansoura University | N/A |
| Completed | Older Adult Effectiveness of 2 Treatments NCT03916926 | Case Western Reserve University | N/A |
| Completed | Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma NCT05576142 | University of Pavia | — |
| Completed | Effects of a Hydroxyapatite-based Mouth Gel on Calcium Content of Plaque NCT03956992 | Dr. Joachim Enax | N/A |
| Unknown | Assessment of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique NCT03433157 | Hacettepe University | N/A |
| Completed | Pharmacokinetics of Advantage Arrest in Children NCT04186663 | Advantage Silver Dental Arrest, LLC | Phase 2 |
| Withdrawn | Occlusal Compensation After the Hall Technique NCT04001153 | University of Dundee | — |
| Completed | Management of Molar Incisor Hypomineralization With Silver Diamine Fluoride or SMART NCT03862014 | Hacettepe University | N/A |
| Completed | The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract NCT04136639 | Al-Azhar University | N/A |
| Unknown | Selective Caries Removal (SCR) Versus Pulpotomy in Preventing Pulp Necrosis and Apical Periodontitis NCT04672070 | National University Hospital, Singapore | N/A |
| Completed | Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite NCT04059250 | University of California, San Francisco | N/A |
| Completed | Resin Bulkfill Dual-Cured of Proximal Restoration. Clinical Trial NCT05013853 | Universidad Nacional Andres Bello | N/A |
| Completed | Effect of 12 Months Supplementation With a Symbiotic Lozenge on Caries Increment in Healthy Children NCT03928587 | Chr Hansen | N/A |
| Suspended | Non-restorative Cavity Control in Anterior Cavitated Caries Lesion of Primary Teeth NCT03785730 | Universidade Ibirapuera | N/A |
| Completed | 2-year Caries Clinical Study: Arginine Fluoride-Free Toothpastes vs. NaF Toothpaste NCT05560945 | Colgate Palmolive | Phase 3 |
| Unknown | DIMOH: New Digital Methods for Monitoring Oral Health. An in Vivo Assessment NCT04050306 | University of Copenhagen | — |
| Completed | Pulp Protection in Selective Carious Tissue Removal NCT04250142 | University of Talca | N/A |
| Completed | The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances NCT04186065 | Hiroko Nagaoka | — |
| Recruiting | Carious Tissue Selective Removal on Permanent Posterior Teeth. NCT04533113 | Juan Gonzalo Olivieri | N/A |
| Completed | Improving Dental Health Among Toddlers in the Dominican Republic NCT04101617 | Universidad Iberoamericana | N/A |
| Completed | Comparative Effectiveness of School-based Caries Prevention NCT03442309 | NYU College of Dentistry | N/A |
| Completed | Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care NCT04317768 | Jordan University of Science and Technology | N/A |
| Completed | Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride NCT03770286 | Children's Hospital Los Angeles | N/A |
| Completed | Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients NCT03802669 | October University for Modern Sciences and Arts | — |
| Completed | Impact of Minimally Invasive Restorative Techniques on Pregnant Women Oral Health Related Quality of Life NCT04619264 | Nourhan M.Aly | Phase 2 |
| Unknown | Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Control NCT03732040 | Cairo University | N/A |
| Unknown | Grape Seeds Versus Standard Measures for Prevention of Caries Incidence NCT03724578 | Cairo University | Phase 1 |
| Unknown | Personalized Caries Management Versus Standard of Care for Preventing Incidence of Caries in Young Egyptian Ad NCT03731780 | Cairo University | N/A |
| Completed | Effectiveness of the Intraligamentary Anesthesia and Inferior Alveolar Nerve Block on Pain During Dental Treat NCT04563351 | University Medicine Greifswald | N/A |
| Completed | Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions NCT04052685 | burcu gözetici | N/A |
| Unknown | Is Xylitol Toothpaste Effective in Preventing Tooth Decay? NCT04096599 | Dr. Gillian Lee | N/A |
| Completed | Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART NCT03788616 | Marina F Fahmy, MD | Phase 3 |
| Unknown | Interdental Microbiota Among Adolescents NCT03700840 | Université Montpellier | N/A |
| Completed | Evaluation of CAMBRA Versus ICCMS Caries Risk Assessment Models Acquisition On Treatment Plan NCT03668093 | Cairo University | N/A |
| Unknown | Dietary Influences On Caries Index Among Sudanese And Egyptian Adult Population NCT03566953 | Cairo University | — |
| Unknown | Efficacy of Fluor Protector S in the Prevention in Adolescents NCT03720379 | Medical University of Warsaw | N/A |
| Completed | Child Discomfort and Parental Acceptability of Silver Diamine Fluoride and Alternative Restorative Treatment NCT04654624 | Nourhan M.Aly | Phase 2 / Phase 3 |
| Completed | The Influence of Simple, Low-Cost Chemistry Intervention Videos: A Randomized Trial of Children's Preferences NCT04971317 | NYU Langone Health | N/A |
| Unknown | Knowledge, Attitude and Practice of a Group of Egyptian Dental Interns Toward Caries Risk Assessment NCT03609034 | Cairo University | — |
| Completed | The Incidence of IV Fluid Over-administration in Pediatric Dental Surgeries When Infusion Pumps Are Employed NCT03312452 | University of Saskatchewan | N/A |
| Completed | Survival of Endocrowns Made From Different Ceramics NCT03542019 | University of Jordan | N/A |
| Unknown | Knowledge, Attitude, And Practice In A Group Of Egyptian Dentists Towards Preventive Measures In Pediatric Den NCT03556865 | Cairo University | — |
| Completed | Evaluation of Oral Plaque Removal Utilizing an Adjunct Enzyme Pre-rinse NCT04512482 | Indiana University | Phase 2 |
| Completed | Evaluation of Anti-biofilm Effects of Ferumoxytol (Feraheme) Using an in Situ Biofilm Demineralization Model NCT03678012 | University of Pennsylvania | EARLY_Phase 1 |
| Completed | Evaluation of the Clinical Performance of Reinforced Glass Ionomer Restorations NCT04288791 | Al-Azhar University | N/A |
| Completed | Implementing a Participatory, Multi-level Intervention to Improve Asian American Health Study NCT03438045 | NYU College of Dentistry | N/A |
| Completed | BEhavioral EConomics for Oral Health iNnovation Trial NCT03576326 | University of California, San Francisco | N/A |
| Unknown | Efficiency of Different Modes of Universal Adhesive NCT04271150 | Hacettepe University | N/A |
| Completed | Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study NCT02873585 | University of North Carolina, Chapel Hill | N/A |